Signaling Gateway - 9 May 2008
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0M40EI
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Signaling Update is a one-stop online resource designed to keep you
in touch with the latest and most exciting research in cell
signaling. New content is uploaded every Friday.
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Bio-Rad
The Profinia(TM) Protein Purification System from Bio-Rad
is an automated system designed for affinity purification
and desalting of recombinant tagged proteins, yielding purified
samples in as little as 30 minutes. For more information, visit:
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhM0ED
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In Signaling Update this week:
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Featured Article
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NF-kappaB IN HYPOXIA: AND NOW FOR SOMETHING COMPLETELY DIFFERENT
The transcription factor NF-kappaB induces the expression of
HIF-1alpha, providing a link between innate immunity and the hypoxic
response.
Original research paper: Nature advance online publication 23 April
2008 (doi:10.1038/nature06905)
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0vP0ER
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Selected Updates
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METASTASIS: BRINGING UP THE REAR
Blocking the function of the tetraspanin CD151 in vivo prevents
tumor dissemination by inhibiting migration and access to the
vasculature (intravasation) at primary tumor sites.
Original research paper: Cancer Cell 13, 221-234 (2008)
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhN0EE
MOLECULAR NEUROSCIENCE: STRESS HORMONES TRK NEURONS INTO SURVIVAL
The neuroprotective effects of glucocorticoids are mediated by the
activation of the neurotrophin receptor TrkB in rats.
Original research paper: Proc. Natl Acad. Sci. USA 105, 4862-4867 (2008)
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhO0EF
HOST RESPONSE: INNATE MIMICRY
A new class of virulence factors have been identified that are used
by bacterial pathogens to interfere with Toll-like receptor (TLR)
signaling.
Original research paper: Nature Med. 14, 399-406 (2008)
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhP0EG
More Updates:
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0vO0EQ
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Research Library
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TGF-beta-INDUCED Foxp3 INHIBITS TH17 CELL DIFFERENTIATION BY
ANTAGONIZING RORgammat FUNCTION
Nature 453, 236-240 (2008)
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0Bubc0ET
TRANSCRIPTIONAL CONTROL OF HUMAN p53-REGULATED GENES
Nature Reviews Molecular Cell Biology 9, 402-412 (2008)
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhQ0EH
A ROLE FOR UBIQUITIN IN THE SPLICEOSOME ASSEMBLY PATHWAY
Nature Structural & Molecular Biology 15, 444-451 (2008)
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhR0EI
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Signaling News
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CHEMISTS SPIN A WEB OF DATA
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0Buad0ET
A chemist running a computer server is solving one of his colleagues'
biggest frustrations by providing the community with an open-access
source of chemical information on millions of molecules. The
ChemSpider service scans open-access sources, including PubChem and
Wikipedia, for chemical data. It compiles the publicly available
information in a single location, and allows users to follow links to
the original source material.
More News
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0Crw0E8
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Gateway Updates
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THE FUNCTIONAL GLYCOMICS GATEWAY - MAY UPDATE
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BKHW0E8
The Functional Glycomics Gateway is a comprehensive FREE online
resource to keep you abreast of the latest findings in the field.
This month's update features:
Angiogenesis: A small candy for the tumor
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhF0E5
and
Intravenous immunoglobulin (IVIG): Straight from bench to bedside
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhJ0EA
Sign up to receive the monthly table of contents e-alert for the
Functional Glycomics Update.
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BJYw0Ev
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Signaling Job of the Week
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Postdoctoral Fellow
Employer: Mayo Clinic
Location: Jacksonville, FL
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BuhS0EJ
A postdoctoral position is available in the laboratory of Dr. Storz
to study protein kinase D (PKD) function in human cancer using both,
cell-based and animal models at the Mayo Clinic Comprehensive Cancer
Center in Jacksonville, Florida. The project will comprise analysis
of cell signaling and gene induction in tumor cells and tumor biology
in mice.
More Jobs:
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0BnjC0Ew
To advertise a job in this spot, please contact Naturejobs.
http://ealerts.nature.com/cgi-bin24/DM/y/ekmU0Xztnp0H2W0vqs0Et
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