May 2008 Volume 22 Number 5, pp 891 - 1091
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EDITORIAL
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Therapy-related acute myeloid leukaemia with mutated NPM1: treatment
induced or de novo in origin?
B Falini
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Bux20EL
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MEETING REPORT
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Meeting report: myelodysplastic syndromes at ASH 2007
R Itzykson, C Gardin and P Fenaux
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Bux30EM
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Bux40EN
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SPOTLIGHT REVIEWS
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Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis
E K Thomas, J A Cancelas, Y Zheng and D A Williams
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Bux50EO
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Bux60EP
Life expectancy and prognostic factors in the classic
BCR//ABL-negative myeloproliferative disorders
F Cervantes, F Passamonti and G Barosi
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Bux70EQ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Bux80ER
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REVIEWS
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Cooperating gene mutations in acute myeloid leukemia: a review of the
literature
A Renneville, C Roumier, V Biggio, O Nibourel, N Boissel, P Fenaux and
C Preudhomme
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyA0Eb
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyB0Ec
Experimental non-ATP-competitive therapies for chronic myelogenous
leukemia
A Quintas-Cardama
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyC0Ed
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyD0Ee
The bone marrow niche: habitat to hematopoietic and mesenchymal stem
cells, and unwitting host to molecular parasites
Y Shiozawa, A M Havens, K J Pienta and R S Taichman
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyE0Ef
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyF0Eg
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ORIGINAL ARTICLES
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NPM1 mutations in therapy-related acute myeloid leukemia with
uncharacteristic features
M T Andersen, M K Andersen, D H Christiansen and J Pedersen-Bjergaard
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyG0Eh
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyH0Ei
Expression of myeloperoxidase enhances the chemosensitivity of
leukemia cells through the generation of reactive oxygen species and
the nitration of protein
Y Sawayama, Y Miyazaki, K Ando, K Horio, C Tsutsumi, D Imanishi, H
Tsushima, Y Imaizumi, T Hata, T Fukushima, S Yoshida, Y Onimaru, M
Iwanaga, J Taguchi, K Kuriyama and M Tomonaga
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyI0Ej
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyJ0Ek
A phase II study of 5-azacitidine for patients with primary and
post-essential thrombocythemia/polycythemia vera myelofibrosis
A Quintas-Cardama, W Tong, H Kantarjian, D Thomas, F Ravandi, S
Kornblau, T Manshouri, J E Cortes, G Garcia-Manero and S Verstovsek
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyK0El
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyL0Em
Sphingosine kinase-1 is a downstream regulator of imatinib-induced
apoptosis in chronic myeloid leukemia cells
E Bonhoure, A Lauret, D J Barnes, C Martin, B Malavaud, T Kohama, J V
Melo and O Cuvillier
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyM0En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyN0Eo
Lack of the leukocyte-associated Ig-like receptor-1 expression in
high-risk chronic lymphocytic leukaemia results in the absence of a
negative signal regulating kinase activation and cell division
A Poggi, S Catellani, A Bruzzone, F Caligaris-Cappio, M Gobbi and M R
Zocchi
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyO0Ep
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyP0Eq
Minimal residual disease (MRD) analysis in the non-MRD-based ALL
IC-BFM 2002 protocol for childhood ALL: is it possible to avoid MRD
testing?
E Fronkova, E Mejstrikova, S Avigad, K W Chik, L Castillo, S Manor, L
Reznickova, T Valova, K Zdrahalova, O Hrusak, Y Jabali, M Schrappe, V
Conter, S Izraeli, C K Li, B Stark, J Stary and J Trka
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyQ0Er
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyR0Es
NK resistance of tumor cells from multiple myeloma and chronic
lymphocytic leukemia patients: implication of HLA-G
G Maki, G M Hayes, A Naji, T Tyler, E D Carosella, N Rouas-Freiss and
S A Gregory
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyS0Et
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyT0Eu
Vaccination of B-CLL patients with autologous dendritic cells can
change the frequency of leukemia antigen-specific CD8+ T cells as well
as CD4+CD25+FoxP3+ regulatory T cells toward an antileukemia response
I Hus, M Schmitt, J Tabarkiewicz, S Radej, K Wojas, A Bojarska-Junak,
A Schmitt, K Giannopoulos, A Dmoszynska and J Rolinski
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyU0Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyV0Ew
hNUDC promotes the cell proliferation and differentiation in a
leukemic cell line via activation of the thrombopoietin receptor (Mpl)
Y-S Tang, Y-P Zhang and P Xu
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyW0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyX0Ey
A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051
induces apoptosis in T-cell lymphomas
S Balasubramanian, J Ramos, W Luo, M Sirisawad, E Verner and J J Buggy
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyY0Ez
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20BuyZ0E1
DNA methylation profiles in diffuse large B-cell lymphoma and their
relationship to gene expression status
B L Pike, T C Greiner, X Wang, D D Weisenburger, Y-H Hsu, G Renaud, T
G Wolfsberg, M Kim, D J Weisenberger, K D Siegmund, W Ye, S Groshen, R
Mehrian-Shai, J Delabie, W C Chan, P W Laird and J G Hacia
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buya0E8
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyb0EA
Genetic aberrations and survival in plasma cell leukemia
R E Tiedemann, N Gonzalez-Paz, R A Kyle, R Santana-Davila, T
Price-Troska, S A Van Wier, W J Chng, R P Ketterling, M A Gertz, K
Henderson, P R Greipp, A Dispenzieri, M Q Lacy, S V Rajkumar, P L
Bergsagel, A K Stewart and R Fonseca
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyc0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyd0EC
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LETTERS TO THE EDITOR
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MT1-MMP as a downstream target of BCR-ABL/ABL interactor 1 signaling:
polarized distribution and involvement in BCR-ABL-stimulated leukemic
cell migration
X Sun, Y Li, W Yu, B Wang, Y Tao and Z Dai
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buye0ED
Mature B-cell lymphoblastic leukemia with MLL rearrangement: an
uncommon and distinct subset of childhood acute leukemia
N Blin, F Mechinaud, P Talmant, R Garand, P Boutard, N Dastugue, E A
McIntyre, J L Harousseau and H Avet-Loiseau
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyf0EE
Chronic myeloproliferative diseases with concurrent BCR-ABL junction
and JAK2V617F mutation
K Hussein, O Bock, K Theophile, A Seegers, H Arps, O Basten, K-H
Grips, J Franz-Werner, G Busche and H Kreipe
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyg0EF
Marked improvement of severe progressive systemic sclerosis after
transplantation of mesenchymal stem cells from an allogeneic
haploidentical-related donor mediated by ligation of CD137L
M Christopeit, M Schendel, J Foll, L P Muller, G Keysser and G Behre
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyh0EG
Characterization of three t(3;8)(q27;q24) translocations from diffuse
large B-cell lymphomas
P Bertrand, C Maingonnat, J M Picquenot, N Dastugue, D Penther, L
Ysebaert, C Maisonneuve, H Tilly and C Bastard
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyi0EH
Downregulation of microRNA-142 by proto-oncogene LMO2 and its
co-factors
W Yuan, W Sun, S Yang, J Du, C-L Zhai, Z-Q Wang, J Zhang and T-H Zhu
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyj0EI
Spectrum of p53 mutations in low-grade B-cell malignancies
T Bromidge, S Johnson and D Howe
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyk0EJ
V[lambda] genes in chronic lymphocytic leukaemia: highly skewed V gene
segment usage with similar CDR3 sequences
A Abusedra, R Joshi, A Bybee, J F Apperley and S D Wagner
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyl0EK
Characterization of acute myeloid leukemia with PTPN11 mutation: the
mutation is closely associated with NPM1 mutation but inversely
related to FLT3/ITD
H-A Hou, W-C Chou, L-I Lin, C-Y Chen, J-L Tang, M-H Tseng, C-F Huang,
R-J Chiou, F-Y Lee, M-C Liu and H-F Tien
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buym0EL
Childhood T-cell non-Hodgkin's lymphoma, colorectal carcinoma and
brain tumor in association with cafe-au-lait spots caused by a novel
homozygous PMS2 mutation
C P Kratz, C M Niemeyer, E Juttner, M Kartal, A Weninger, A
Schmitt-Graeff, U Kontny, M Lauten, S Utzolino, J Radecke, C Fonatsch
and K Wimmer
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyn0EM
Do [beta]2 microglobulin levels affect survival of newly diagnosed
myeloma patients with translocation t(4;14) or 17p13 deletion treated
with conventional chemotherapy?
W J Chng, S Jacobus and R Fonseca
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyo0EN
Rituximab in CD20 positive multiple myeloma
J M Bergua, C Cabrera, E G Arteta and J Prieto
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyp0EO
Reply to `Rituximab activity in CD20-positive multiple myeloma'
A Gozzetti, A Fabbri, S Lazzi, M Bocchia and F Lauria
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyq0EP
Reply to Gozzetti et al.
J M Bergua, C Cabrera, E G Arteta and J Prieto
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyr0EQ
Tumor-derived IL-6 may contribute to the immunological defect in CLL
A G S Buggins, P E M Patten, J Richards, N S B Thomas, G J Mufti and S
Devereux
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buys0ER
The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias
M P Tschan, U Gullberg, D Shan, B E Torbett, M F Fey and A Tobler
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyt0ES
Interferon-[alpha] is able to maintain complete molecular remission
induced by imatinib after its discontinuation
A M Carella
http://ealerts.nature.com/cgi-bin24/DM/y/ekrQ0Xztnp0Hi20Buyu0ET
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