June 2008 Volume 15 Number 6, pp 947 - 1085
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This alert is sponsored by Immunochemistry Technologies
Are your cells apoptotic or necrotic? FLICA will tell you.
http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BH7D0ET
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Laboratory Investigation presents:
'Understanding the development of human bladder cancer by using a
whole-organ genomic mapping strategy'
http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKH0Ed
Can this disease be detected earlier? Genome-wide mapping of human
bladder cancer has identified key genetic risk areas for cancer
development and provides new insight into early genetic origins of
cancer.
View the complete article:
http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKH0Ed
http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0Fnv0E5
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Cell Death & Differentiation: Special Issues
An essential resource...
Throughout the year, Cell Death & Differentiation publishes a select
number of
issues that comprise reviews dedicated to the understanding of
specific areas
in cell death. Special Issues for 2008 include reviews on immunity,
hypoxia, and tumors. Read a select number of articles from the Special
Issues collection online at:
http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BVde0Ez
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REVIEWS
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Cancer stem cells - old concepts, new insights
L Vermeulen, M R Sprick, K Kemper, G Stassi and J P Medema
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKI0Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKJ0Ef
The dark side of a tumor suppressor: anti-apoptotic p53
R U Janicke, D Sohn and K Schulze-Osthoff
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKK0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKL0Eh
Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a
breakthrough in anticancer therapy?
V Labi, F Grespi, F Baumgartner and A Villunger
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKM0Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKN0Ej
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ORIGINAL PAPERS
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Inhibition of SHP2 leads to mesenchymal to epithelial transition in
breast cancer cells
X-D Zhou and Y M Agazie
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKO0Ek
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKP0El
Viral pro-survival proteins block separate stages in Bax activation
but changes in mitochondrial ultrastructure still occur
J R Cross, A Postigo, K Blight and J Downward
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKQ0Em
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKR0En
The molecular archaeology of a mitochondrial death effector: AIF in
Drosophila
N Joza, K Galindo, J A Pospisilik, P Benit, M Rangachari, E E Kanitz,
Y Nakashima, G G Neely, P Rustin, J M Abrams, G Kroemer and J M
Penninger
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKS0Eo
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKT0Ep
In several cell types tumour suppressor p53 induces apoptosis largely
via Puma but Noxa can contribute
E M Michalak, A Villunger, J M Adams and A Strasser
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKU0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKV0Er
DJ-1 modulates UV-induced oxidative stress signaling through the
suppression of MEKK1 and cell death
J-S Mo, M-Y Kim, E-J Ann, J-A Hong and H-S Park
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKW0Es
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKX0Et
Bax siRNA promotes survival of cultured and allografted granule cell
precursors through blockade of caspase-3 cleavage
S S Zhokhov, A Desfeux, N Aubert, A Falluel-Morel, A Fournier, V
Laudenbach, H Vaudry and B J Gonzalez
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKY0Eu
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKZ0Ev
The SCFFSN-1 ubiquitin ligase controls germline apoptosis through
CEP-1//p53 in C. elegans
M X Gao, E H Liao, B Yu, Y Wang, M Zhen and W B Derry
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKa0E3
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKb0E4
BIM and other BCL-2 family proteins exhibit cross-species conservation
of function between zebrafish and mammals
C A Jette, A M Flanagan, J Ryan, U J Pyati, S Carbonneau, R A Stewart,
D M Langenau, A T Look and A Letai
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKc0E5
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKd0E6
The interaction of DIAP1 with dOmi//HtrA2 regulates cell death in
Drosophila
F S Khan, M Fujioka, P Datta, T Fernandes-Alnemri, J B Jaynes and E S
Alnemri
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKe0E7
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKf0E8
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BOOK REVIEW
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How to study neuroprotection?
P Tucci and G Bagetta
http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0BvKg0EA
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Molecular Therapy focus on RNAi as a Therapeutic Strategy
http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0Bu1U0EP
FREE access to various articles from the world's leading journals.
Presented by Molecular Therapy, this special web-focus gathers
together top articles on RNAi originally published in Molecular
Therapy, Nature, Nature Medicine, and British Journal of Cancer, and
offers several of them to you FREE for a limited time!
Visit http://ealerts.nature.com/cgi-bin24/DM/y/ekwq0Xztnp0Hhr0Bu1U0EP
to access this special web focus today.
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