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World Stem Cell Summit 2010

Monday, April 28, 2008

[StemCells] G-CSF Side Effects



Side Effects of Cell Therapy 28.04.2008

Granulocyte colony-stimulating factorRussian hematologists found out
that injections, causing formation of additional stem cells, resulted
in serious side effects.

Medics prescribe injections of granulocyte colony-stimulating
factor (G-CSF) to healthy people, who are donors of stem cells, or
patients, who need additional mature blood cells. Researchers found
out that permanent introduction of G-CSF into an organism change
functions of many genes, regulating cell division and interactions.

Healthy donors complained about ostealgia, head aches and
general fatigability. Medics also registered splenic ruptures,
accumulation of hemopoietic cell and other serious troubles.

Laboratory animals showed disappointing results: 22 mice out of
40 died and 8 gained tumors. Scientists detected changes in activity
of many genes and found out that stem cells of bone marrow may carry
a malignant blood disease.

http://www.russia-ic.com/news/show/6254/


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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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