May 2008 Volume 4 Number 5
Visit Nature Clinical Practice Rheumatology online to browse the journal.
Now available at http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0pMu0Em
"Officially endorsed by the Asia Pacific League of Associations for 
Rheumatology"
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NATURE IMMUNOLOGY
FOCUS ON NATURAL KILLER CELLS
Natural killer cells influence immune responses to tumors, infections 
and pregnancy. Nature Immunology presents a series of specially 
commissioned articles that focus on natural killer cells and their 
far-reaching effects on diverse cell types and biological responses. 
The web focus, free for six months, also includes highlights of recent 
research findings, an annotated list of classic articles and links to 
selected NPG papers pertinent to this field.
For more information visit
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BssN0Eu
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EDITORIAL
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Are all DMARDs equivalent?
Peter E Lipsky
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrO0Ev
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VIEWPOINTS
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A critical look at the role of self-management for people with arthritis 
and other chronic diseases
Richard H Osborne, Joanne E Jordan and Anne Rogers
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrP0Ew
Issues concerning the biological repair of intervertebral disc degeneration
Baogan Peng
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrQ0Ex
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RESEARCH HIGHLIGHTS
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New transgenic mouse model of spontaneous autoimmune arthritis
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrR0Ey
Sphingosine 1 phosphate is a key mediator of inflammation in primary 
Sjogren's syndrome
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrS0Ez
Successful treatment of collagen-induced arthritis with cell-cycle 
inhibitors
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrT0E1
Beneficial effects of aldosterone blockade in a mouse model of lupus 
nephritis
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrU0E2
A valid and sensitive patient-based disease activity score for RA
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrV0E3
Mouse studies shed light on pathogenesis of Lyme arthritis
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrW0E4
Duloxetine treatment is effective in women with fibromyalgia
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrX0E5
Cathepsin K is a potential therapeutic target for autoimmune arthritis
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrY0E6
Sildenafil benefits patients with PAH related to connective tissue 
disease
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0BtrZ0E7
In Briefs
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btra0EF
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GUIDELINES SUMMARY
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Canadian recommendations for the management of spondyloarthritis address 
many different levels of patient care
Jurgen Braun
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrb0EG
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PRACTICE POINT
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Is teriparatide or alendronate the best treatment for glucocorticoid-induced 
osteoporosis?
Anthony D Woolf and Kristina Akesson
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrc0EH
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CLINICAL ADVANCE
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Is sitaxsentan a good therapeutic option for pulmonary arterial 
hypertension associated with connective tissue disease?
Yannick Allanore
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrd0EI
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REVIEWS
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Drug Insight: choosing a drug treatment strategy for women with 
osteoporosis-an evidence-based clinical perspective
Piet P Geusens, Christian H Roux, David M Reid, Willem F Lems, 
Silvano Adami, Jonathan D Adachi, Philip N Sambrook, Kenneth G Saag, 
Nancy E Lane and Marc C Hochberg
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btre0EJ
Therapy Insight: preserving fertility in cyclophosphamide-treated patients 
with rheumatic disease
Mary Anne Dooley and Raj Nair
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrf0EK
Therapy Insight: cardiovascular disease in pediatric systemic lupus 
erythematosus
Christy Sandborg, Stacy P Ardoin and Laura Schanberg
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrg0EL
Surgery Insight: orthopedic treatment options in rheumatoid arthritis
Beat R Simmen, Earl R Bogoch and Jorg Goldhahn
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrh0EM
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CASE STUDY
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A paraneoplastic case of palmar fasciitis and polyarthritis syndrome
Muhammad Haroon and Mark Phelan
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btri0EN
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ARTICLE RESPONSES
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Kyphoplasty is not a nonpharmacologic management option for the 
minimization of fracture risk in osteoporosis
Fergus E McKiernan
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrj0EO
Author response to "Kyphoplasty is not a nonpharmacologic management 
option for the minimization of fracture risk in osteoporosis"
Joseph M Lane and Julie T Lin
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrk0EP
Editor's note
http://ealerts.nature.com/cgi-bin24/DM/y/ekaS0Xztnp0HjN0Btrl0EQ
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