April 2008 Volume 9 Number 4
Visit Nature Reviews Molecular Cell Biology online to browse the journal.
Now available at http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0bZF0E4
Please note that you need to be a subscriber to enjoy full text access to Nature Reviews Molecular Cell Biology online. To purchase a subscription, please visit:
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0a8b0Ew
Alternatively, to recommend a subscription to your library, please visit
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0lln0ED
*********************************************************************
Nature Reviews Molecular Cell Biology Impact Factor: 31.354*
(*Journal Citation Reports, Thomson, 2007)
*********************************************************************
=====================================================================
IT'S NOW FREE TO POST YOUR VACANCY ON
naturejobs.com http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0bZD0E2
It's the breakthrough you've been waiting for. Naturejobs.com — the scientific jobs board from Nature —
now lets you advertise your vacancy completely FREE OF CHARGE
Go to http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BGJp0EA or telephone:
Europe: +44 (0) 20 78434961
US: + 1 800 9897718
=====================================================================
=====================================================================
Looking for talented Cell Biologists?
The Signaling Gateway is a free online resource, rich in cell signaling
information. Highlighting a vacancy through The Signaling Gateway is an
effective way to reach thousands of qualified researchers in this field.
Click here for more information.
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BktC0Eh
To advertise your vacancy on The Signaling Gateway please contact
mailto:naturejobs@nature.com
=====================================================================
=====================================================================
Special Web Focus Issue from Cell Research:
DNA Damage Responses and Genome Maintenance
Visit the Cell Research web focus to read the latest on the genome maintenance
systems involved in DNA damage detection, signaling, response and repair.
Throughout this web focus featured articles encompass:
- DNA replication
- Excision repair
- Recombination
- DNA damage tolerance
- Transcription
- Mismatch repair
- Genomic instability and cancer
View this web focus today by visiting: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVa0En
=====================================================================
=====================================================================
This month's FEATURED article:
Tracking the ends: a dynamic protein network controls the fate of microtubule tips
Anna Akhmanova and Michel O. Steinmetz
p309 | doi:10.1038/nrm2369
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVb0Eo
=====================================================================
From the editors
p263 | doi:10.1038/nrm2387
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVc0Ep
=====================================================================
----------------------
RESEARCH HIGHLIGHTS
----------------------
Cancer biology: Warburg effect revisited
p264 | doi:10.1038/nrm2384
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVd0Eq
Membrane trafficking: Ceramide buds in
p265 | doi:10.1038/nrm2381
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVe0Er
Nuclear transport: Signalling and transport converge
p265 | doi:10.1038/nrm2386
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVf0Es
Membrane trafficking: GTPases stack up
p266 | doi:10.1038/nrm2365
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVg0Et
Chromosome biology: Transcription at the edge
p266 | doi:10.1038/nrm2377
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVh0Eu
Gene expression: Translation in real time
p266 | doi:10.1038/nrm2382
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVi0Ev
IN BRIEF
Cytoskeleton | Stem cells | RNA silencing
p267 | doi:10.1038/nrm2380
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVj0Ew
Protein secretion: An unconventional route
p268 | doi:10.1038/nrm2367
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVk0Ex
Gene expression: Cohesin branches out
p268 | doi:10.1038/nrm2371
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVl0Ey
TECHNOLOGY WATCH
Ghost fish | Fluorescent cycling
p268 | doi:10.1038/nrm2372
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVm0Ez
Cell division: Inn a pinch
p269 | doi:10.1038/nrm2383
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVn0E1
AN INTERVIEW WITH...
Alex Rich
p270 | doi:10.1038/nrm2373
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVo0E2
----------------------
REVIEWS
----------------------
Exiting the Golgi complex
Maria Antonietta De Matteis and Alberto Luini
p273 | doi:10.1038/nrm2378
The trans-Golgi network (TGN) is a major sorting centre for lipids and proteins that lies at the crossroads of endocytic and exocytic pathways. Recent studies have started to elucidate the molecular machineries that function in sorting and trafficking at the TGN.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVp0E3
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVq0E4
The role of oxygen availability in embryonic development and stem cell function
M. Celeste Simon and Brian Keith
p285 | doi:10.1038/nrm2354
Oxygen is required for the survival of most organisms. Recent advances show that it is not only important for the promotion of cellular bioenergetics and metabolism, but also that it is an essential signal that regulates cell fate during embryonic development and in stem cells.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVr0E5
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVs0E6
Regulation of DNA repair throughout the cell cycle
Dana Branzei and Marco Foiani
p297 | doi:10.1038/nrm2351
Recent studies have provided insights into the mechanisms that regulate DNA repair in specific cell-cycle phases and the pathways that ensure cell-cycle progression or arrest in normal and cancerous cells. Understanding how DNA repair is modulated during the cell cycle has important applications.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVt0E7
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVu0E8
Tracking the ends: a dynamic protein network controls the fate of microtubule tips
Anna Akhmanova and Michel O. Steinmetz
p309 | doi:10.1038/nrm2369
How do cytoskeletal components interact to control cellular processes? At the growing microtubule plus ends, microtubule plus-end tracking proteins (+TIPs) regulate different aspects of cell architecture by controlling microtubule dynamics, microtubule interactions with cellular structures and signalling factors, and forces exerted on microtubule networks.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVv0EA
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVb0Eo
How membrane proteins sense voltage
Francisco Bezanilla
p323 | doi:10.1038/nrm2376
Recent studies have provided insights into the mechanisms of voltage sensing and have identified new voltage-dependent proteins. Characterizing the general features of voltage sensors might lead to the discovery of further membrane proteins that are regulated by voltage.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVw0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVx0EC
----------------------
PERSPECTIVES
----------------------
SCIENCE AND SOCIETY
Childhood of a phoenix: modern biology in Eastern and South-Eastern Europe
Bojan Zagrovic and Ivan Dikic
p333 | doi:10.1038/nrm2368
In the shadow of societal upheaval and transformation, Eastern and South-Eastern European countries have been undergoing major reforms of their scientific and academic landscapes. Although the reforms have been slow, the success of several molecular biology institutes has highlighted what can be achieved.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVy0ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqVz0EE
OPINION
Multifunctional deadenylase complexes diversify mRNA control
Aaron C. Goldstrohm and Marvin Wickens
p337 | doi:10.1038/nrm2370
Deadenylases shorten mRNA poly(A) tails and thereby regulate mRNA translation and decay. Recent studies have shown that these factors form different complexes. The recruitment of multifunctional deadenylase complexes to target mRNAs provides a unique node to control mRNA translation and decay.
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqV10Ez
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0BqV20E1
=====================================================================
Cell Migration Gateway - Leading the way in cell migration
The Cell Migration Knowledgebase (CMKB) provides a freely available,
extensive and curated collection of information about proteins involved
in cell migration. Recently, the CMKB has been enhanced to provide easier
access and more information. It now includes information about genes,
protein domains, protein structure, interactions, phosphorylation sites and
pathways for 6800 proteins from 800 protein families.
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0hkE0ER
A collaboration between the Cell Migration Consortium and Nature Publishing Group
=====================================================================
You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at:
http://ealerts.nature.com/cgi-bin24/DM/y/ejks0Xztnp0Hjf0Zzu0EG
(You will need to log in to be recognised as a nature.com registrant).
For further technical assistance, please contact our registration department:
registration@nature.com
For print subscription enquiries, please contact our subscription department:
subscriptions@nature.com
For other enquiries, please contact our customer feedback department:
feedback@nature.com
Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA
Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne -
San Diego - San Francisco - Washington - New York - Boston
(c) Copyright 2008 Nature Publishing Group
=====================================================================
