13 March 2008 Volume 452 Number 7184, pp127-252
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EDITORIALS
----------------------
Growing pains p127
The fight against agricultural diseases in the United States has been
boosted by fresh funds and a national monitoring network. But these
advances are being undermined by inflexible bureaucracy.
doi:10.1038/452127a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyj0Ek
Markets can save forests pp127-128
With the right infrastructure, the forces threatening to destroy the
world's trees could be their salvation.
doi:10.1038/452127b
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyk0El
On message, off target p128
Official advice on vaccination is too often poorly transmitted.
doi:10.1038/452128a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyl0Em
----------------------
RESEARCH HIGHLIGHTS
----------------------
Research highlights pp130-131
doi:10.1038/452130a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpym0En
----------------------
JOURNAL CLUB
----------------------
Journal club p131
John Church
doi:10.1038/452131a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyn0Eo
----------------------
NEWS
----------------------
Stem-cell claim gets cold reception pp132-
Carbon nanotubes used to reprogramme adult human cells?
David Cyranoski and Monya Baker
doi:10.1038/452132a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyo0Ep
Pacific "dwarf" bones cause controversy p133
Some researchers think the Palau finds are the remains of youngsters.
Rex Dalton
doi:10.1038/452133a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyp0Eq
Brazil goes to war against logging pp134-135
It represents half of the world's rainforest and is home to one-third
of Earth's species, yet the Amazon has one of the highest rates of
deforestation.
Jeff Tollefson looks at efforts to curb the problem.
doi:10.1038/452134a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp1O0E6
Q&A
All eyes on the Amazon p137
Meteorologist and biosphere scientist Carlos Nobre of Brazil's
National Institute for Space Research in São Paulo has modelled the
effects of deforestation and global warming on the Amazon. Nature
talks to him about the future of the unique rainforest.
Jeff Tollefson
doi:10.1038/452137a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyr0Es
Sidelines pp138
Scribbles on the margins of science.
doi:10.1038/452138a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpys0Et
Snapshot: Flooding the canyon pp138
Water diverted to stir sediments and save chub.
Anna Petherick
doi:10.1038/452138b
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyt0Eu
Libya progresses on HIV pp138
Integrated approach could be model for Africa.
Declan Butler
doi:10.1038/452138c
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyu0Ev
Probe readies for dip into geyser on Enceladus pp139
Astrobiologists hope for clues about moon's temperature.
Eric Hand
doi:10.1038/452139a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyv0Ew
Seattle laboratory arsonist faces prison stretch pp141
doi:10.1038/452141a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyw0Ex
Giant telescope gets double vision pp141
doi:10.1038/452141b
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyx0Ey
Officials downplay vaccine's link with autism pp141
doi:10.1038/452141c
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyy0Ez
British government to demand clinical trial data pp141
doi:10.1038/452141d
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpyz0E1
Jules Verne sets off for space station pp141
doi:10.1038/452141e
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy10En
Charity to focus scientists' skills on the needy pp141
doi:10.1038/452141f
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy20Eo
Chinese scientists lead panda genome project pp141
doi:10.1038/452141g
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy30Ep
----------------------
NEWS FEATURE
----------------------
Astronomy: Eyes as big as the sky pp142-145
Three teams are racing each other to build the next generation of
telescopes that would dramatically dwarf the largest on Earth today.
Eric Hand checks out the competition.
doi:10.1038/452142a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy40Eq
----------------------
BUSINESS FEATURE
----------------------
Business: Stepping out pp146
A surprisingly large number of university-inspired patents may be
going to industry instead.
Rex Dalton reports.
doi:10.1038/452146a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy50Er
----------------------
NEWS FEATURE
----------------------
Bioterror: The green menace pp148-150
Huanglongbing, a disease that could devastate the US citrus industry,
pits national security against plant pathologists looking to battle
natural outbreaks, Ewen Callaway reports.
doi:10.1038/452148a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy60Es
----------------------
CORRESPONDENCE
----------------------
Poor countries left behind in rush to claim sea floor p151
Morten Sorensen
doi:10.1038/452151a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy70Et
Directive will unleash new generation of coal polluters p151
Mark Avery et al.
doi:10.1038/452151b
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpy80Eu
How academic corporatism can lead to dictatorship p151
G. A. Clark
doi:10.1038/452151c
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzA0E5
Results of rush to sequence genomes may be nonsense p151
Thomas C. Erren, Paul Cullen and Michael Erren
doi:10.1038/452151d
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzB0E6
----------------------
BOOKS AND ARTS
----------------------
One long argument p153
Revisiting ancient Greek debates about the natural world should
broaden biologists' horizons.
Armand M. Leroi reviews Creationism and its Critics in Antiquity
by David Sedley
doi:10.1038/452153a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzC0E7
Storming the language barrier p154
Frans B. M. de Waal reviews The Simian Tongue: The Long Debate about
Animal Language by Gregory Radick
doi:10.1038/452154a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzD0E8
Exhibition: A protein ghost etched in glass p155
Marta Paterlini
doi:10.1038/452155a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzE0EA
Census of cyberspace censoring pp155-156
Bruce Schneier reviews Access Denied
doi:10.1038/452155b
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzF0EB
Exhibition: Beauty meets utility at MoMA p156
Josie Glausiusz
doi:10.1038/452156a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzG0EC
Correction p156
doi:10.1038/452156b
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzH0ED
----------------------
NEWS AND VIEWS
----------------------
Drug discovery: Fresh hope to can the worms pp157-158
Parasitic worms kill many livestock, and the drugs used against them
are becoming less effective. The discovery of a class of compounds
that kills worms resistant to existing drugs is thus a welcome
development.
Roger K. Prichard and Timothy G. Geary
doi:10.1038/452157a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzI0EE
Cosmology: Patchy solutions pp158-161
The Universe seems to be expanding ever faster -- a phenomenon
generally ascribed to the influence of 'dark energy'. But might
the observed acceleration be a trick of the light in an inhomogeneous
Universe?
George Ellis
doi:10.1038/452158a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzJ0EF
50 & 100 Years Ago p159
doi:10.1038/452159a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzK0EG
Physical chemistry: Did life grind to a start? pp161-162
Many solids can adopt two mirror-image crystal forms, and often grow
as mixtures of both. A curious mechanism of crystal growth might
explain why some mixtures convert into one form when subjected to
grinding.
J. Michael McBride and John C. Tully
doi:10.1038/452161a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzL0EH
Nitrogen cycle: Out of reach pp162-163
Denitrifying bacteria and hungry plants do sterling work in disposing
of the nitrates that we pump into rivers and streams. But as the
excess influx goes up and up, the efficiency of removal goes down and
down.
Sybil Seitzinger
doi:10.1038/452162a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzM0EI
Biochemistry: Radicals by reduction pp163-164
Many enzymes convert their substrates into organic radicals to allow
challenging reactions to occur. A microbial enzyme does so by simple
electron transfer, casting fresh light on enzyme evolution.
Joseph T. Jarrett
doi:10.1038/452163a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzN0EJ
----------------------
NEWS AND VIEWS Q&A
----------------------
Earth science: Geomagnetic reversals pp165-167
Earth's magnetic field is unstable. Not only does it vary in
intensity, but from time to time it flips, with the poles reversing
sign. Much of this behaviour remains a mystery, but a combination of
geomagnetic observations with theoretical studies has been providing
enlightenment.
David Gubbins
doi:10.1038/452165a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzO0EK
----------------------
REVIEW
----------------------
Genetic basis of fitness differences in natural populations pp169-175
Hans Ellegren and Ben C. Sheldon
doi:10.1038/nature06737
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzP0EL
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzQ0EM
----------------------
BRIEF COMMUNICATIONS ARISING
----------------------
Complex speciation of humans and chimpanzees ppE3-E4
John Wakeley
doi:10.1038/nature06805
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzR0EN
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzS0EO
Patterson et al. reply pE4
Nick Patterson et al.
doi:10.1038/nature06806
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzT0EP
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzU0EQ
----------------------
ARTICLES
----------------------
A new class of anthelmintics effective against drug-resistant
nematodes pp176-180
The discovery of a new chemical class of anthelmintics that seem to
act through a novel mechanism is reported. These small molecules are
efficacious against various livestock pathogenic nematode species.
Ronald Kaminsky et al.
doi:10.1038/nature06722
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzV0ER
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzW0ES
Pyruvate kinase M2 is a phosphotyrosine-binding protein pp181-186
A mechanism whereby the M2 isoform of the glycolytic enzyme pyruvate
kinase (PKM2) can be regulated by tyrosine kinase signalling pathways
through an ability to bind tyrosine phosphorylated proteins is
revealed.
Heather R. Christofk et al.
doi:10.1038/nature06667
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzX0ET
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzY0EU
SATB1 reprogrammes gene expression to promote breast tumour growth and
metastasis pp187-193
Hye-Jung Han, Jose Russo, Yoshinori Kohwi and Terumi Kohwi-Shigematsu
doi:10.1038/nature06781
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0BpzZ0EV
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpza0Ec
----------------------
LETTERS
----------------------
Reflected light from sand grains in the terrestrial zone of a
protoplanetary disk pp194-197
In the standard model of terrestrial planet formation, interstellar
grains of typical size ~0.1 µm are expected to grow to millimetre,
centimetre or even metre-sized objects rather quickly. Unfortunately,
such evolved disks are hard to observe. This paper reports
observations of grains that have grown to about millimetre size or
larger in the terrestrial zone of a 3-Myr-old star.
William Herbst et al.
doi:10.1038/nature06671
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzb0Ed
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzc0Ee
Hierarchical self-assembly of DNA into symmetric supramolecular
polyhedra pp198-201
DNA molecules have been programmed to fold into a basic structural
unit, with four, twenty or sixty copies of that unit then assembling
according to reaction conditions into either tetrahedra, dodecahedra or
buckyballs, respectively. Other complex structures should also be
accessible using this strategy.
Yu He et al.
doi:10.1038/nature06597
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzd0Ef
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpze0Eg
Stream denitrification across biomes and its response to anthropogenic
nitrate loading pp202-205
About a quarter of the nitrogen added to the biosphere is exported
from rivers to the ocean or inland basins, indicating substantial
sinks for nitrogen must exist in the landscape. Data from nitrogen
stable isotope tracer experiments across 72 streams suggests that the
total uptake of nitrate is related to ecosystem photosynthesis, and
that denitrification is related to ecosystem respiration. A stream
network model demonstrates that excess nitrate in streams elicits a
disproportionate increase in the fraction of nitrate that is exported
to receiving waters and reduces the relative role of small versus
large streams as nitrate sinks.
Patrick J. Mulholland et al.
doi:10.1038/nature06686
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzf0Eh
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzg0Ei
Influence of the Gulf Stream on the troposphere pp206-209
The Gulf Stream's influence on the atmosphere is examined using a
combination of operational weather analyses and satellite observations.
The results indicate that the Gulf Stream anchors a rain band in which
upward motion of air penetrates deep into the upper troposphere, well
above the near surface portion of the atmosphere. These mechanisms
provide a pathway by which the Gulf Stream can affect local climate,
and possibly also climate in remote regions.
Shoshiro Minobe et al.
doi:10.1038/nature06690
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzh0Ej
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzi0Ek
Diversity and productivity peak at intermediate dispersal rate in
evolving metacommunities pp210-214
An investigation into the role of dispersal in determining diversity
and productivity over evolutionary time scales using the bacterium
Pseudomonas fluorescens shows that adaptive radiation driven by
environmental heterogeneity and dispersal leads to the de novo evolution
of a positive relationship between functional diversity and productivity,
which both peak at intermediate dispersal rates.
P. A. Venail et al.
doi:10.1038/nature06554
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzj0El
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzk0Em
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA
methylation patterning p215
In Arabidopsis, a map of methylated cytosines is generated at single
base pair resolution by combining bisulphite treatment of genomic DNA
with ultra high throughput sequencing.
Shawn J. Cokus et al.
doi:10.1038/nature06745
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzl0En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzm0Eo
Adaptive coding of visual information in neural populations pp220-224
Individual neurons at multiple stages of the visual system adapt to
constant features in the visual scene, but how adaptation alters
population dynamics is unknown. This paper shows that in the macaque
primary visual cortex (V1), adaptation to briefly presented oriented
stimuli alters pairwise correlations, with implications for the
efficiency of the population code.
Diego A. Gutnisky and Valentin Dragoi
doi:10.1038/nature06563
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzn0Ep
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzo0Eq
A skin microRNA promotes differentiation by repressing 'stemness' p225
A microRNA (miR 203) that promotes differentiation of stratified epithelial
stem cells by restricting their proliferation and inducing cell cycle exit
is identified. One of its targets is p63, which regulates stem cells maintenance
in skin, and it is shown that miR2 3 works by repressing p63 expression.
Rui Yi, Matthew N. Poy, Markus Stoffel & Elaine Fuchs
doi:10.1038/nature06642
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2I0E1
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2J0E2
The M2 splice isoform of pyruvate kinase is important for cancer
metabolism and tumour growth pp230-233
Many tumour cells express the M2 form of pyruvate kinase rather than
the usual M1 form. PKM2 is now shown to promote tumorigenesis and
switch the cellular metabolism to increased lactate production and
reduced oxygen consumption, recapitulating key aspects of the Warburg
effect.
Heather R. Christofk et al.
doi:10.1038/nature06734
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzp0Er
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzq0Es
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes p234
The membrane protein UNC93B interacts with intracellular Toll-like
receptors TLR7 and TLR9. This paper shows that UNC93B specifically
controls TLR trafficking from the endoplasmic reticulum to the
endolysosome but is not required for ligand recognition or
signal initiation.
You-Me Kim et al.
doi:10.1038/nature06726
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzr0Et
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzs0Eu
An allylic ketyl radical intermediate in clostridial amino-acid
fermentation pp239-242
The pathogenic bacterium Clostridium difficile thrives by fermentation
of L leucine to ammonia, CO2, isovalerate, and isocaproate under anaerobic
conditions. Ketyl radicals have been proposed to mediate a key reaction
catalysed by an iron–sulphur cluster containing dehydratase, which
requires activation by ATP dependent electron transfer from a second
iron–sulphur protein. A kinetically competent product related allylic
ketyl radical bound to the dehydratase using electron paramagnetic
resonance spectroscopy is identified. These results suggest that other 2
hydroxyacyl CoA dehydratases (and the related benzoyl CoA reductases)
may employ ketyl radical intermediates. The absence of radical generators
makes these enzymes unprecedented in biochemistry.
Jihoe Kim, Daniel J. Darley, Wolfgang Buckel and Antonio J. Pierik
doi:10.1038/nature06637
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzt0Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzu0Ew
Transcriptional repression mediated by repositioning of genes to the
nuclear lamina p243
Artificially tethering a chromosomal region to the inner nuclear
membrane (INM) of mammalian cells results in repression of gene
transcription in conjunction with accumulation of lamin and INM proteins,
but not nuclear pore complexes, at the tethered region.
H. Singh et al.
doi:10.1038/nature06727
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzv0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzw0Ey
----------------------
ERRATUM
----------------------
The X-ray crystal structure of RNA polymerase from Archaea p248
Akira Hirata, Brianna J. Klein and Katsuhiko S. Murakami
doi:10.1038/nature06844
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bpzx0Ez
----------------------
NATURE JOBS
----------------------
Prospect
Prospects p249
The Howard Hughes Medical Institute has unveiled a programme to offer
start-up funds for young biomedical scientists.
Paul Smaglik
doi:10.1038/nj7184-249a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2T0ED
Career View
Daniel Kelly, scientific director, Burnham Institute for Medical
Research, Orlando, Florida p250
Science director appointed to Burnham Institute's new Florida
location.
Virginia Gewin
doi:10.1038/nj7184-250a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2V0EF
Sunny view for Florida life sciences p250
Florida adds to growing collection of high-profile institutes.
Virginia Gewin
doi:10.1038/nj7184-250b
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2X0EH
David versus Goliath p250
It can be a battleground in the lab.
Zachary Lippman
doi:10.1038/nj7184-250c
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2Z0EJ
----------------------
FUTURES
----------------------
The protocol p252
Your children deserve the best.
Ralph Greco
doi:10.1038/452252a
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2b0ER
------------------------------
ADVANCE ONLINE PUBLICATION
------------------------------
12 March 2008
Opposing effects of polyglutamine expansion on native protein
complexes contribute to SCA1
Janghoo Lim et al.
doi:10.1038/nature06731
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2e0EU
Functional metagenomic profiling of nine biomes
Elizabeth A. Dinsdale et al.
doi:10.1038/nature06810
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2h0EX
Sophisticated particle-feeding in a large Early Cambrian crustacean
Thomas H. P. Harvey and Nicholas J. Butterfield
doi:10.1038/nature06724
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2k0Ea
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
Eriko Michishita et al.
doi:10.1038/nature06736
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2n0Ed
Impaired TH17 cell differentiation in subjects with autosomal dominant
hyper-IgE syndrome
Joshua D. Milner et al.
doi:10.1038/nature06764
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2q0Eg
SAR11 marine bacteria require exogenous reduced sulphur for growth
H. James Tripp et al.
doi:10.1038/nature06776
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2t0Ej
09 March 2008
Following translation by single ribosomes one codon at a time
Jin-Der Wen et al.
doi:10.1038/nature06716
http://ealerts.nature.com/cgi-bin24/DM/y/eje30Xztnp0HjB0Bp2w0Em
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