(may also want to see other post on nanotechnology dna damage)
Stem cells safety made into nerve tissues
Date: February 18, 2008
Korean scientists on Monday (Feb. 18) said they have successfully
used nano and bio technologies to grow nerve, muscle and liver
tissues from stem cells.
The discovery made by a team led by Park Se-pill, a life engineering
professor at Cheju National University, used magnetized nano
particles to insert genes into stem cells of laboratory animals that
differentiated into specific tissues.
The research published in the latest issue of the international Stem
Cells and Development journal is noteworthy because it did not use
the dangerous retrovirus or inefficient chemical-electrical
techniques that are currently employed in these experiments.
Retroviruses are used in so-called gene delivery systems, but they
are believed to cause serious side effect since the tainted stem
cells could trigger cancer and immune disorders. In the chemical-
electrical technique, a high percentage of genes are lost in the
delivery process.
Park's team, which includes researchers from Mirae Biotech Research
Institute in Seoul and Konkuk University, said they used 20 nanometer
particles that were combined with specific genes of laboratory mice
and placed on top of a plate that emitted a magnetic field. This
process allowed the genes to be safety mixed with stem cells and
grown into nerve, muscle and liver tissues. A nanometer is one-
billionth of a meter.
Stem cell research may result in cures for numerous diseases such as
Alzheimer's and diabetes and could help people suffering from
paralysis caused by damaged vertebrae.
Park said the success rate using nano technology reached 45 percent,
much higher than the 15 percent attained by the chemical-electrical
technique.
He added that in the 50 laboratory experiments conducted, all genes
transplanted into the stem cells survived and grew into tissue.
The team, meanwhile, said that while nanotechnology is used in cell
research, its experiments were the first to use the technology to
help differentiate stem cells.
The technique has been submitted for patent protection.
http://www.kois.
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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