February 2008 Volume 27 Number 10, pp 1345 - 1500
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Cell Death & Differentiation Special Issue on Immunity
In this issue of CDD, several reviews focus on the role of death, at
the cellular level, in immunity.
Select reviews on:
- NK cells at the interface between innate and adaptive immunity
- Apoptosis and the immune system
- Clearance of apoptotic cells by phagocytes
- Mechanisms of granule-dependent killing
Visit CDD online to view these articles
http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bm580EB
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What is Oncogene Reviews?
Oncogene Reviews - an in-depth look into hot topics in cancer
research.
Each year Oncogene publishes a series of review issues that take a
closer look into the most current research and advances that are
impacting the study of cancer. Visit
http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Hi30EF
to read the latest articles from Oncogene Reviews!
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ORIGINAL ARTICLES
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Histone deacetylase inhibitors induce mitotic slippage
F E Stevens, H Beamish, R Warrener and B Gabrielli
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowa0Ey
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowb0Ez
Regulation of mitotic exit by the RNF8 ubiquitin ligase
V Plans, M Guerra-Rebollo and T M Thomson
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowc0E1
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowd0E2
BH3-only protein BIK induces caspase-independent cell death with
autophagic features in Bcl-2 null cells
R Rashmi, S G Pillai, S Vijayalingam, J Ryerse and G Chinnadurai
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowe0E3
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowf0E4
Histone deacetylase inhibitor apicidin downregulates DNA
methyltransferase 1 expression and induces repressive histone
modifications via recruitment of corepressor complex to promoter
region in human cervix cancer cells
J S You, J K Kang, E K Lee, J C Lee, S H Lee, Y J Jeon, D H Koh, S H
Ahn, D-W Seo, H Y Lee, E-J Cho and J-W Han
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowg0E5
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowh0E6
Activation of the mitochondrial death pathway is commonly mediated by
a preferential engagement of Bak
D Neise, V Graupner, B F Gillissen, P T Daniel, K Schulze-Osthoff, R U
Janicke and F Essmann
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowi0E7
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowj0E8
CBAP interacts with the un-liganded common [beta]-subunit of the
GM-CSF//IL-3//IL-5 receptor and induces apoptosis via mitochondrial
dysfunction
C-J Kao, Y-J Chiang, P-H Chen, K-R Lin, P-I Hwang, H-F Yang-Yen and J
J-Y Yen
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowk0EA
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowl0EB
SAG//ROC2//RBX2 is a HIF-1 target gene that promotes HIF-1[alpha]
ubiquitination and degradation
M Tan, Q Gu, H He, D Pamarthy, G L Semenza and Y Sun
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowm0EC
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bown0ED
Functionally distinct monomers and trimers produced by a viral
oncoprotein
S-H Chung, R S Weiss, K K Frese, B V V Prasad and R T Javier
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowo0EE
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowp0EF
Bfl-1//A1 functions, similar to Mcl-1, as a selective tBid and Bak
antagonist
M J Simmons, G Fan, W-X Zong, K Degenhardt, E White and C Gelinas
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowq0EG
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowr0EH
Gadd45[beta] is a pro-survival factor associated with stress-resistant
tumors
A Engelmann, D Speidel, G W Bornkamm, W Deppert and C Stocking
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bows0EI
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowt0EJ
Distinct FAK-Src activation events promote [alpha]5[beta]1 and
[alpha]4[beta]1 integrin-stimulated neuroblastoma cell motility
L Wu, J A Bernard-Trifilo, Y Lim, S-T Lim, S K Mitra, S Uryu, M Chen,
C J Pallen, N-Kv Cheung, D Mikolon, A Mielgo, D G Stupack and D D
Schlaepfer
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowu0EK
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowv0EL
The transcriptional repressor NIPP1 is an essential player in
EZH2-mediated gene silencing
M Nuytten, L Beke, A Van Eynde, H Ceulemans, M Beullens, P Van
Hummelen, F Fuks and M Bollen
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Boww0EM
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowx0EN
Epigenetic silencing of CXCL12 increases the metastatic potential of
mammary carcinoma cells
M K Wendt, A N Cooper and M B Dwinell
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowy0EO
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bowz0EP
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SHORT COMMUNICATION
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Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer
cells
C Lagadec, E Adriaenssens, R A Toillon, V Chopin, R Romon, F Van
Coppenolle, H Hondermarck and X Le Bourhis
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bow10EC
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bow20ED
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ONCOGENOMICS
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Deregulated Wnt//[beta]-catenin program in high-risk neuroblastomas
without MYCN amplification
X Liu, P Mazanek, V Dam, Q Wang, H Zhao, R Guo, J Jagannathan, A
Cnaan, J M Maris and M D Hogarty
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bow30EE
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bow40EF
Sonic Hedgehog regulates Hes1 through a novel mechanism that is
independent of canonical Notch pathway signalling
W J Ingram, K I McCue, T H Tran, A R Hallahan and B J Wainwright
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bow50EG
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejR70Xztnp0Hjk0Bow60EH
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