In this issue of CDD, several reviews focus on the role of death, at
the cellular level, in immunity.
Select reviews on:
- NK cells at the interface between innate and adaptive immunity
- Apoptosis and the immune system
- Clearance of apoptotic cells by phagocytes
- Mechanisms of granule-dependent killing
Visit CDD online to view these articles
http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0Bm580Ee
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What is Oncogene Reviews?
Oncogene Reviews - an in-depth look into hot topics in cancer
research.
Each year Oncogene publishes a series of review issues that take a
closer look into the most current research and advances that are
impacting the study of cancer.Visit
http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0Hi30Ei
to read the latest articles from Oncogene Reviews!
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ONCOGENE
February 2008 Volume 27 Number 8, pp 1033 - 1188
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COMMENTARY
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For IRES trans-acting factors, it is all about location
S M Lewis and M Holcik
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZL0Ec
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZM0Ed
----------------------
ORIGINAL ARTICLES
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A chemical inhibitor of PPM1D that selectively kills cells
overexpressing PPM1D
S Rayter, R Elliott, J Travers, M G Rowlands, T B Richardson, K
Boxall, K Jones, S Linardopoulos, P Workman, W Aherne, C J Lord and A
Ashworth
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZN0Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZO0Ef
ATF-2 controls transcription of Maspin and GADD45[alpha] genes
independently from p53 to suppress mammary tumors
T Maekawa, Y Sano, T Shinagawa, Z Rahman, T Sakuma, S Nomura, J D
Licht and S Ishii
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZP0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZQ0Eh
Defective TGF-[beta] signaling sensitizes human cancer cells to
rapamycin
N Gadir, D N Jackson, E Lee and D A Foster
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZR0Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZS0Ej
Stromal inactivation of BMPRII leads to colorectal epithelial
overgrowth and polyp formation
H Beppu, O N Mwizerwa, Y Beppu, M P Dattwyler, G Y Lauwers, K D Bloch
and A M Goldstein
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZT0Ek
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZU0El
HPV-16 E5 oncoprotein upregulates lipid raft components caveolin-1 and
ganglioside GM1 at the plasma membrane of cervical cells
F A Suprynowicz, G L Disbrow, E Krawczyk, V Simic, K Lantzky and R
Schlegel
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZV0Em
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZW0En
Zebrafish pten genes have overlapping and non-redundant functions in
tumorigenesis and embryonic development
A Faucherre, G S Taylor, J Overvoorde, J E Dixon and J den Hertog
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZX0Eo
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZY0Ep
Forced expression of a constitutively active form of Stat3 in mouse
epidermis enhances malignant progression of skin tumors induced by
two-stage carcinogenesis
K S Chan, S Sano, K Kataoka, E Abel, S Carbajal, L Beltran, J
Clifford, M Peavey, J Shen and J DiGiovanni
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZZ0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZa0Ex
Aggressive breast cancer cells are dependent on activated Abl kinases
for proliferation, anchorage-independent growth and survival
D Srinivasan, J T Sims and R Plattner
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZb0Ey
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZc0Ez
Regulation of cyclin D1 expression by mTORC1 signaling requires
eukaryotic initiation factor 4E-binding protein 1
J Averous, B D Fonseca and C G Proud
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZd0E1
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZe0E2
Astrocyte elevated gene-1 activates cell survival pathways through
PI3K-Akt signaling
S-G Lee, Z-Z Su, L Emdad, D Sarkar, T F Franke and P B Fisher
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZf0E3
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZg0E4
The apoptosis-inducing effect of gastrin on colorectal cancer cells
relates to an increased IEX-1 expression mediating NF-[kappa]B
inhibition
S Sebens Muerkoster, A V Rausch, A Isberner, J Minkenberg, E
Blaszczuk, M Witt, U R Folsch, F Schmitz, H Schafer and A Arlt
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZh0E5
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZi0E6
Telomere attrition induces a DNA double-strand break damage signal
that reactivates p53 transcription in HTLV-I leukemic cells
A Datta and C Nicot
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZj0E7
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZk0E8
Oncogenic pathways impinging on the G2-restriction point
F Foijer, M Simonis, M van Vliet, L Wessels, R Kerkhoven, P K Sorger
and H te Riele
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZl0EA
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZm0EB
The PEA-15//PED protein protects glioblastoma cells from glucose
deprivation-induced apoptosis via the ERK//MAP kinase pathway
A Eckert, B C Bock, K E Tagscherer, T L Haas, K Grund, J Sykora, C
Herold-Mende, V Ehemann, M Hollstein, H Chneiweiss, O D Wiestler, H
Walczak and W Roth
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZn0EC
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZo0ED
----------------------
SHORT COMMUNICATIONS
----------------------
Regulation of BAG-1 IRES-mediated translation following chemotoxic
stress
H C Dobbyn, K Hill, T L Hamilton, K A Spriggs, B M Pickering, M J
Coldwell, C H de Moor, M Bushell and A E Willis
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZp0EE
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZq0EF
The activity of hsp90[alpha] promoter is regulated by NF-[kappa]B
transcription factors
M Ammirante, A Rosati, A Gentilella, M Festa, A Petrella, L Marzullo,
M Pascale, M A Belisario, A Leone and M C Turco
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZr0EG
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZs0EH
Phosphorylation by Akt disables the anti-oncogenic activity of YB-1
A G Bader and P K Vogt
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZt0EI
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZu0EJ
ATM-dependent nuclear accumulation of IKK-[alpha] plays an important
role in the regulation of p73-mediated apoptosis in response to
cisplatin
K Yoshida, T Ozaki, K Furuya, M Nakanishi, H Kikuchi, H Yamamoto, S
Ono, T Koda, K Omura and A Nakagawara
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZv0EK
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBd0Xztnp0Hjk0BnZw0EL
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