14 February 2008 Volume 451 Number 7180, pp745-864
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Targeting lipid signalling in disease
A free poster from Nature Reviews Molecular Cell Biology
This free poster from Nature Reviews Molecular Cell Biology provides
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network can be exploited pharmacologically to attenuate proliferative,
inflammatory and metabolic diseases.
Access this poster at:
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----------------------
EDITORIALS
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Nuclear security undervalued p745
The world's only agency for assuring global standards and security in
nuclear installations needs an upgrade. This cannot be done on the
cheap.
doi:10.1038/451745a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZy0Ej
Genetics benefits at risk pp745 - 746
A rogue senator needs to be bypassed.
doi:10.1038/451745b
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZz0Ek
Down on the farms p746
Efforts by the Ministry of Defence to block offshore wind farms is at
odds with Britain's long-term security.
doi:10.1038/451746a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ10EX
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RESEARCH HIGHLIGHTS
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Research highlights pp748 - 749
doi:10.1038/451748a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ20EY
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JOURNAL CLUB
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Journal club p749
John Shepherd
doi:10.1038/451749a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ30EZ
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NEWS
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Atomic agency to give verdict on Iran pp750 - 751
The International Atomic Energy Agency is wrapping up its inquiry into
Iran's nuclear activities and is expected to report its findings on 20
February. Declan Butler analyses how close the state is to nuclear
weapons capability.
Declan Butler
doi:10.1038/451750a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ40Ea
Chinese astronomers look to Antarctic p752
Frozen heights of Dome A to play host to observatory.
Rachel Courtland
doi:10.1038/451752a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ50Eb
Natural gas back in favour with US power companies pp753 - 753
Coal gets cold shoulder as utilities anticipate carbon legislation.
Jeff Tollefson
doi:10.1038/451753a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ60Ec
Lessons from the dark side pp755 - 755
What role did German scientists and their funding organization play in
supporting Nazi policies during 1933?45? In a bid to find out,
Germany's research council, the DFG, sponsored a seven-year
investigation into its own history that ended last month. One of the
historians who led the study, Ulrich Herbert of the University of
Freiburg, discusses the findings.
Alison Abbott
doi:10.1038/451755a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ70Ed
Sidelines pp756 - 756
Scribbles on the margins of science.
doi:10.1038/451756a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnZ80Ee
From Russia with scintillation pp756 - 757
The story of CERN's crucial crystals.
Geoff Brumfiel
doi:10.1038/451756b
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaA0Eu
Biofuels might create more emissions than they save pp759 - 759
doi:10.1038/451759a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaB0Ev
Collectors claim trade treaty is obstructive pp759 - 759
doi:10.1038/451759b
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaC0Ew
Illumina unveils genome sequence of African male pp759 - 759
doi:10.1038/451759c
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaD0Ex
Head of US environmental health agency resigns pp759 - 759
doi:10.1038/451759d
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaE0Ey
Cash crisis puts Sunshine Project in the shade pp759 - 759
doi:10.1038/451759e
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaF0Ez
Europe's lab finally arrives at the space station pp759 - 759
doi:10.1038/451759f
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaG0E1
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NEWS FEATURES
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Speed dating: You have 4 minutes to choose your perfect mate pp760 - 762
What is the secret to finding the right partner? Two researchers are
using unconventional techniques to find out.
Matt Kaplan investigates the science of speed dating.
doi:10.1038/451760a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaH0E2
Profile: Meet Exhibit I pp763 - 765
George Church has made a name for himself as an 'information
exhibitionist'.
Erika Check Hayden explores how the technological sage is turning his
gaze to the next horizon — you.
doi:10.1038/451763a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaI0E3
Scientific publishing: Identity crisis pp766 - 767
Chinese authors are publishing more and more papers, but are they
receiving due credit and recognition for their work? Not if their
names get confused along the way.
Jane Qiu reports.
doi:10.1038/451766a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaJ0E4
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CORRESPONDENCE
----------------------
Students find out that bacteria can cheat too p768
Nel C. Venzon, Jr
doi:10.1038/451768a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaK0E5
European adventures did nothing for people of Egypt p768
Ninad Bondre
doi:10.1038/451768b
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaL0E6
Funding cuts leave 'golden era' looking tarnished p768
Phil Bland
doi:10.1038/451768c
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaM0E7
Future stars of the lab need realistic role models p768
Sarah C. Hubbard
doi:10.1038/451768d
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaN0E8
Freeing more carbon will accelerate global warming p768
Neil Wilson
doi:10.1038/451768e
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaO0EA
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BOOKS AND ARTS
----------------------
A close look at conflict pp769 - 770
Psychology, neuroscience and physiology are missing from a new
sociological study of violence.
Margo Wilson and Martin Daly reviews Violence: A Micro-Sociological
Theory by Randall Collins
doi:10.1038/451769a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaP0EB
The invisible revolution pp770 - 771
Vincent Dusastre reviews Nanosciences: La Revolution Invisible by
Christian Joachim and Laurence Plevert
doi:10.1038/451770a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaQ0EC
Exhibition: Essence of creation p771
Isabelle Kaufmann reviews Genesis — The Art of Creation
doi:10.1038/451771a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaR0ED
Genomes evolve, but how? pp771 - 772
Axel Meyer reviews The Origins of Genome Architecture by Michael Lynch
doi:10.1038/451771b
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaS0EE
Festival: Neural networking in Manhattan p772
Giovanni Frazzetto reviews Brainwave festival
doi:10.1038/451772a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaT0EF
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NEWS AND VIEWS
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Granular matter: Static in motion pp773 - 774
Wind-blown desert sands can charge up spontaneously. But although sand
flow and the forces on charged bodies are well studied separately,
surprisingly little is known of what happens when the two combine.
Troy Shinbrot and Hans J. Herrmann
doi:10.1038/451773a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaU0EG
Evolutionary biology: A first for bats pp774 - 775
Which came first as bats evolved -- flight or echolocation? Newly
described fossils favour the flight-first hypothesis. But these
creatures may have been otherwise equipped for flying at night.
John Speakman
doi:10.1038/451774a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaV0EH
Astrophysics: A story of singular degeneracy pp775 - 777
Astronomers have a choice of two models of how type Ia supernovae
arise. The progenitor for one of these huge stellar explosions has now
been discovered, bringing a definitive judgement a little closer.
Edward P. J. van den Heuvel
doi:10.1038/451775a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaW0EI
50 & 100 Years Ago p776
doi:10.1038/451776a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaX0EJ
Molecular biology: Cohesin branches out pp777 - 778
The cohesin complex -- best known for its role in cell division --
does not rest between divisions, and instead participates in
regulating gene expression. How it does this is only now becoming
clear.
Frank Uhlmann
doi:10.1038/451777a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaY0EK
Catalysis: The art of splitting water pp778 - 779
Plants produce oxygen from water, but the same chemical reaction is
hard to achieve synthetically. A new family of catalysts could breathe
fresh life into the quest for artificial photosynthesis.
Thomas J. Meyer
doi:10.1038/451778a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnaZ0EL
Evolutionary biology: Darwin in the fossils pp779 - 780
Adaptation by natural selection is thought to drive evolution.
Although it has been difficult to confirm this process in the fossil
record, evidence has been there all along: we just haven't been
looking properly.
Andrew P. Hendry
doi:10.1038/451779a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnaa0ES
Obituary: M. Judah Folkman (1933-2008) p781
Scientist, surgeon and creator of the field of angiogenesis research.
Michael Klagsbrun and Marsha A. Moses
doi:10.1038/451781a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnab0ET
----------------------
BRIEF COMMUNICATIONS ARISING
----------------------
Nitrogen saturation and net ecosystem production pE1
An De Schrijver et al.
doi:10.1038/nature06578
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnac0EU
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnad0EV
Ecologically implausible carbon response? ppE1 - E3
Wim de Vries et al.
doi:10.1038/nature06579
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnae0EW
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnaf0EX
Magnani et al. reply ppE3 - E4
Federico Magnani et al.
doi:10.1038/nature06580
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnag0EY
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnah0EZ
----------------------
ARTICLES
----------------------
The genome of the choanoflagellate Monosiga brevicollis and the origin
of metazoans pp783 - 788
Choanoflagellates occupy an important place on the tree of life, because they
may be the closest unicellular relative to animals. Here the sequencing and
analysis of the genome of the marine choanoflagellate Monosiga brevicollis
illuminates important sequence shuffling in its genes, suggesting that the
common ancestor of both groups already had intron-rich genes.
Nicole King et al.
doi:10.1038/nature06617
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnai0Ea
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnaj0Eb
Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4
signalling pp789 - 795
Ethylene is an important plant hormone regulating biological processes from
flower development to stress responses. It's known that in the presence of
ethylene EIN3 is stabilized and mediates ethylene-regulated gene expression
and morphological responses, and here a mitogen-activated protein kinase (MAPK)
pathway is revealed that acts positively to control EIN3-mediated transcription
in ethylene signalling.
Sang-Dong Yoo et al.
doi:10.1038/nature06543
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnak0Ec
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnal0Ed
Cohesin mediates transcriptional insulation by CCCTC-binding factor p796
Kerstin S. Wendt et al.
Cohesin has a well-established role in sister chromatid cohesion during chromosome
segregation. Here, binding sites for cohesin are mapped in the human genome and are
found to coincide with sites for the transcription insulator protein CTCF. Cohesin
is shown to be required for CTCF function as a transcription insulator, which is
independent of cohesin's function in cohesion.
doi:10.1038/nature06634
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnam0Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnan0Ef
----------------------
LETTERS
----------------------
Discovery of the progenitor of the type Ia supernova 2007on pp802 - 804
Type Ia supernovae are exploding white dwarf stars in a binary system that are
used to measure the accelerated expansion of the Universe, but what triggers the
explosion is unclear. Either the white dwarf could accrete material from a companion
until it exceeds the Chandrasekhar mass, collapses and explodes, or two white dwarfs
could merge, again causing an explosion. But the discovery of the X ray progenitor
of the recent type Ia supernova 2007on seems to favour the accretion model for this
supernova because deep optical images show no sign of this object.
Rasmus Voss and Gijs Nelemans
doi:10.1038/nature06602
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnao0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnap0Eh
Giant magneto-elastic coupling in multiferroic hexagonal manganites
pp805 - 808
When a solid is heated or cooled, its atoms must move around according to the space
group they belong to, although normally the atoms' movements are too small to detect,
with inevitable changes in the solid's electronic properties. Now, for a class of
manganites, various diffraction techniques reveal they undergo an isostructural
transition with very large atomic displacements (around 0.08 angstroms), resulting
in unusually strong magneto elastic coupling, which might explain recently observed
magneto electric phenomena in these manganites.
Seongsu Lee et al.
doi:10.1038/nature06507
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnaq0Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnar0Ej
Microfibre-nanowire hybrid structure for energy scavenging pp809 - 813
To harvest the energy from vibrations caused by footsteps, heart beats, noises and air
flow, what's needed are flexible soft materials that work at low frequencies (<10 Hz).
This simple, low cost approach converts low-frequency friction energy into electricity
using piezoelectric ZnO nanowires grown radially around textile fibres, which could lead
to new fabrics that scavenge energy from light winds and body movement.
Yong Qin, Xudong Wang and Zhong Lin Wang
doi:10.1038/nature06601
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnas0Ek
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnat0El
Sound velocities of majorite garnet and the composition of the mantle
transition region pp814 - 817
Anomalies in the seismic wave velocity and density in the mantle transition region
(400 to 700 km deep) could be explained by either an olivine-rich 'pyrolite' composition
or a pyroxene- and garnet-rich 'piclogite' composition. These authors show that majorite
in a pyrolite composition realistically has sound velocities much lower than those of
earlier model estimates. Pyrolite yields seismic velocities that are generally more
consistent with typical seismological models than those of piclogite.
T. Irifune et al.
doi:10.1038/nature06551
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnau0Em
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnav0En
Primitive Early Eocene bat from Wyoming and the evolution of flight
and echolocation pp818 - 821
The morphology of the ear region of the most primitive bat known (which nevertheless
has fully developed wings) suggests that it could not echolocate, showing that bats
could fly before they acquired their ability to use echolocation to hunt and generally
get around.
Nancy B. Simmons, Kevin L. Seymour, Jorg Habersetzer and
Gregg F. Gunnell
doi:10.1038/nature06549
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnaw0Eo
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnax0Ep
Chaos in a long-term experiment with a plankton community pp822 - 825
An experimental study of a marine planktonic food web that has been monitored for over
eight years showed that the population dynamics in this system are chaotic, implying
that our ability to predict the long-term dynamics of real ecosystems may be limited.
Elisa Beninca et al.
doi:10.1038/nature06512
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnay0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnaz0Er
Removal of phospho-head groups of membrane lipids immobilizes voltage
sensors of K+ channels pp826 - 829
Here sphingomyelinases are used to investigate the role of phospholipids in the
opening of voltage-gated K+ channels, and show that phospholipids affect K+ channel
function by binding to the voltage sensors.
Yanping Xu, Yajamana Ramu and Zhe Lu
doi:10.1038/nature06618
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna10Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna20Ef
A modular switch for spatial Ca2+ selectivity in the calmodulin
regulation of CaV channels p830
Calmodulin is associated with voltage-gated Ca2+ channels, and each of its lobes is
sensitive to changes in the Ca2+ concentration. Here the authors describe a novel
calmodulin-binding motif (NSCaTE) that is present in some Ca2+ channels and that
confers local Ca2+ sensitivity to the N-lobe of calmodulin.
Ivy E. Dick, Michael R. Tadross, Haoya Liang, Lai Hock Tay,
Wanjun Yang & David T. Yue
doi:10.1038/nature06529
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna30Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna40Eh
Co-option of a default secretory pathway for plant immune responses pp835 - 840
Chian Kwon et al.
Plants successfully defend themselves against most fungal attacks, but the underlying
mechanisms remain poorly understood. Here the first SNARE complex in planta is
presented and is suggested to function in a local immune response to pathogens
through focal secretion.
doi:10.1038/nature06545
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna50Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna60Ej
Two levels of protection for the B cell genome during somatic
hypermutation pp841 - 845
B-cell activation by an antigen induces somatic hypermutation of immunoglobulin genes,
giving rise to high-affinity antibodies. Here mutation analysis in germinal-centre B
cells shows that mutagenesis is more widespread than thought previously and provides
indirect evidence that a subset of genes is protected by high-fidelity repair.
Man Liu et al.
doi:10.1038/nature06547
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna70Ek
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bna80El
The structural basis of protein acetylation by the p300/CBP
transcriptional coactivator pp846 - 850
The crystal structure of the histone acetyltransferase domain of p300/CBP and biochemical
data explain the broad substrate specificity of the enzyme and reveal a Theorell Chance
catalytic mechanism distinct from that of other histone acetyltransferases.
Xin Liu et al.
doi:10.1038/nature06546
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbA0Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbB0Ew
The X-ray crystal structure of RNA polymerase from Archaea p851
A crystal structure of archaeal RNA polymerase now allows a comparison of
structures of the transcription machinery between all three domains of life.
Akira Hirata, Brianna J. Klein & Katsuhiko S. Murakami
doi:10.1038/nature06530
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbC0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbD0Ey
----------------------
TECHNOLOGY FEATURES
----------------------
Stem Cells: In search of common ground pp855 - 858
With the number of stem-cell lines rapidly increasing, technology
developers are working to improve systems for culturing and efficient
differentiation -- all with an eye on the clinic.
Nathan Blow reports.
doi:10.1038/451855a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbE0Ez
Stem Cells: Beyond the flat world p856
doi:10.1038/451856a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbF0E1
Stem Cells: A new path to pluripotency p858
doi:10.1038/451858a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbG0E2
Stem cells: Table of suppliers pp859 - 860
doi:10.1038/451859a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbH0E3
----------------------
NATURE JOBS
----------------------
Prospect
Prospects p861
Graduate students strive to unionize, to their advantage and
potentially their detriment.
Gene Russo
doi:10.1038/nj7180-861a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbI0E4
Career View
Alex Dehgan, senior scientist and policy adviser, US Department of
State, Washington DC p862
Diverse experiences in Madagascar, Iraq and Afghanistan prepared new
adviser to the state department for his post.
Virginia Gewin
doi:10.1038/nj7180-862a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbJ0E5
Lab links with southern states p862
Oak Ridge expands mentor protégé programme.
Virginia Gewin
doi:10.1038/nj7180-862b
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbK0E6
Serial postdoc p862
Kicking the postdoc habit.
Jon Yearsley
doi:10.1038/nj7180-862c
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbL0E7
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FUTURES
----------------------
The champagne award p864
Planning for the future.
Gregory Benford
doi:10.1038/451864a
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0BnbM0E8
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ADVANCE ONLINE PUBLICATION
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13 February 2008
Article
Translational control of the innate immune response through IRF-7
Rodney Colina et al.
doi:10.1038/nature06730
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bncn0Eh
Letters
Gamete formation without meiosis in Arabidopsis
Maruthachalam Ravi, Mohan P. A. Marimuthu & Imran Siddiqi
doi:10.1038/nature06557
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bncq0Ek
Transcriptional repression mediated by repositioning of genes to the
nuclear lamina
K. L. Reddy, J. M. Zullo, E. Bertolino & H. Singh
doi:10.1038/nature06727
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnct0En
Facultative cheater mutants reveal the genetic complexity of
cooperation in social amoebae
Lorenzo A. Santorelli et al.
doi:10.1038/nature06558
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bncw0Eq
10 February 2008
Letters
Resistance to therapy caused by intragenic deletion in BRCA2
Stacey L. Edwards et al.
doi:10.1038/nature06548
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bncz0Et
Secondary mutations as a mechanism of cisplatin resistance in
BRCA2-mutated cancers
Wataru Sakai et al.
doi:10.1038/nature06633
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bnc30Ei
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Cell Death & Differentiation Special Issue on Immunity
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bm580E1
In this issue of CDD, several reviews focus on the role of death, at
the cellular level, in immunity.
Select reviews on:
- NK cells at the interface between innate and adaptive immunity
- Apoptosis and the immune system
- Clearance of apoptotic cells by phagocytes
- Mechanisms of granule-dependent killing
Visit CDD online to view these articles FREE of charge.
http://ealerts.nature.com/cgi-bin24/DM/y/ejBg0Xztnp0HjB0Bm580E1
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