March 2008 Volume 128 Number 3, pp 495 - 763
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EDITORIALS
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Clinical Snippets
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Research Snippets
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Editors' Picks
Article:
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JOURNAL CLUB
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Antibody Response in Endemic Pemphigus Foliaceus
Nancy H Kim, Aparche Yang and Robert S Kirsner
Article:
http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKW0EK
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKX0EL
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COMMENTARY
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SMaRT Technology Enables Gene Expression Repair in Skin Gene Therapy
Ulrich R Hengge
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKY0EM
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKZ0EN
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKa0EU
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PERSPECTIVE
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KERATINOCYTES/EPIDERMIS
Outside-in Signaling through Integrins and Cadherins: A Central
Mechanism to Control Epidermal Growth and Differentiation?
Eliane J Muller, Lina Williamson, Carine Kolly and Maja M Suter
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKb0EV
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKc0EW
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKd0EX
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ORIGINAL ARTICLES
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CELL BIOLOGY
Localization of the TIG3 Transglutaminase Interaction Domain and
Demonstration that the Amino-Terminal Region Is Required for TIG3
Function as a Keratinocyte Differentiation Regulator
Ralph Jans, Michael T Sturniolo and Richard L Eckert
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKe0EY
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKf0EZ
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKg0Ea
Synergistic Activation of Human Involucrin Gene Expression by Fra-1
and p300[mdash]Evidence for the Presence of a Multiprotein Complex
James F Crish and Richard L Eckert
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKh0Eb
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKi0Ec
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKj0Ed
Retinoic Acid Increases Aquaporin 3 Expression in Normal Human Skin
Gaelle Bellemere, Otto Von Stetten and Thierry Oddos
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKk0Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKl0Ef
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKm0Eg
Crucial Roles of MZF1 and Sp1 in the Transcriptional Regulation of the
Peptidylarginine Deiminase Type I Gene (PADI1) in Human Keratinocytes
Sijun Dong, Shibo Ying, Toshio Kojima, Masakazu Shiraiwa, Akira
Kawada, Marie-Claire Mechin, Veronique Adoue, Stephane Chavanas, Guy
Serre, Michel Simon and Hidenari Takahara
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKn0Eh
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKo0Ei
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKp0Ej
Melanosome Transfer Promoted by Keratinocyte Growth Factor in Light
and Dark Skin-Derived Keratinocytes
Giorgia Cardinali, Giulia Bolasco, Nicaela Aspite, Giuseppe Lucania,
Lavinia V Lotti, Maria R Torrisi and Mauro Picardo
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKq0Ek
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKr0El
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKs0Em
5[prime] Trans-Splicing Repair of the PLEC1 Gene
Verena Wally, Alfred Klausegger, Ulrich Koller, Hanns Lochmuller,
Sabine Krause, Gerhard Wiche, Lloyd G Mitchell, Helmut Hintner and
Johann W Bauer
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKt0En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKu0Eo
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKv0Ep
CONNECTIVE TISSUE
Integrin [alpha]3[beta]1 Potentiates TGF[beta]-Mediated Induction of
MMP-9 in Immortalized Keratinocytes
John M Lamar, Vandana Iyer and C Michael DiPersio
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKw0Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKx0Er
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKy0Es
GENETICS
Five New CYLD Mutations in Skin Appendage Tumors and Evidence that
Aspartic Acid 681 in CYLD Is Essential for Deubiquitinase Activity
Stephanie Almeida, Caroline Maillard, Peter Itin, Daniel Hohl and
Marcel Huber
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnKz0Et
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK10Eg
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK20Eh
Single-Nucleotide-Specific siRNA Targeting in a Dominant-Negative Skin
Model
Robyn P Hickerson, Frances J D Smith, Robert E Reeves, Christopher H
Contag, Devin Leake, Sancy A Leachman, Leonard M Milstone, W H Irwin
McLean and Roger L Kaspar
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK30Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK40Ej
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK50Ek
Cellular Genomic Maps Help Dissect Pathology in Human Skin Disease
Asifa S Haider, Michelle A Lowes, Mayte Suarez-Farinas, Lisa C Zaba,
Irma Cardinale, Miroslav Blumenberg and James G Krueger
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK60El
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK70Em
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnK80En
Coding and Non-Coding Polymorphisms in Alcohol Dehydrogenase Alters
Protein Expression and Alcohol-Associated Erythema
Lynn K Pershing, Yuexian Chen, Ariana N Tkachuk, Holly L Rausch, Kasia
Petelenz-Rubin, Judy L Corlett and Maurine R Hobbs
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLA0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLB0Ey
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLC0Ez
IMMUNOLOGY/INFECTION
Essential Role of CCR6 in Directing Activated T Cells to the Skin
during Contact Hypersensitivity
Timothy J Paradis, Susan H Cole, Robin T Nelson and Ronald P Gladue
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLD0E1
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLE0E2
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLF0E3
Differential Expression of D-Type Cyclins in HaCaT Keratinocytes and
in Psoriasis
Nora Belso, Marta Szell, Andor Pivarcsi, Kornelia Kis, Bernadett
Kormos, Anna Sz Kenderessy, Attila Dobozy, Lajos Kemeny and Zsuzsanna
Bata-Csorgo
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLG0E4
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLH0E5
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLI0E6
Topical N-acetyl-S-farnesyl-L-cysteine Inhibits Mouse Skin
Inflammation, and Unlike Dexamethasone, its Effects Are Restricted to
the Application Site
Joel S Gordon, Peter M Wolanin, Arnold V Gonzalez, David A Fela, Gopal
Sarngadharan, Karl Rouzard, Eduardo Perez, Jeffry B Stock and Maxwell
B Stock
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLJ0E7
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLK0E8
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLL0EA
Insights into Gene Modulation by Therapeutic TNF and IFN[gamma]
Antibodies: TNF Regulates IFN[gamma] Production by T Cells and
TNF-Regulated Genes Linked to Psoriasis Transcriptome
Asifa S Haider, Jules Cohen, Ji Fei, Lisa C Zaba, Irma Cardinale,
Kikuchi Toyoko, Jurg Ott and James G Krueger
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLM0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLN0EC
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLO0ED
The IgM Anti-Desmoglein 1 Response Distinguishes Brazilian Pemphigus
Foliaceus (Fogo Selvagem) from Other Forms of Pemphigus
Luis A Diaz, Phillip S Prisayanh, David A Dasher, Ning Li, Flor
Evangelista, Valeria Aoki, Gunter Hans-Filho, Vandir dos Santos,
Bahjat F Qaqish and Evandro A Rivitti
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLP0EE
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLQ0EF
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLR0EG
MELANOCYTES/MELANOMA
Phase- and Stage-Related Proportions of T Cells Bearing the
Transcription Factor FOXP3 Infiltrate Primary Melanoma
Giuseppe De Panfilis, Nicoletta Campanini, Marcello Santini, Giovanni
Mori, Elena Tognetti, Roberta Maestri, Mara Lombardi, Elisabetta
Froio, Donata Ferrari and Roberto Ricci
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLS0EH
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLT0EI
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLU0EJ
PHOTOBIOLOGY
The Dose Rate of UVA Treatment Influences the Cellular Response of
HaCaT Keratinocytes
Julie Shorrocks, Nigel D Paul and Trevor J McMillan
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLV0EK
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLW0EL
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLX0EM
TUMOR BIOLOGY
A New Disorder in UV-Induced Skin Cancer with Defective DNA Repair
Distinct from Xeroderma Pigmentosum or Cockayne Syndrome
Satoru Hashimoto, Kiyofumi Egawa, Hironobu Ihn, Ai Igarashi, Tsukasa
Matsunaga, Satoshi Tateishi and Masaru Yamaizumi
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLY0EN
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLZ0EO
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLa0EV
Human Skin Keloid Fibroblasts Display Bioenergetics of Cancer Cells
Annette S Vincent, Than T Phan, Anandaroop Mukhopadhyay, Hwee Y Lim,
Barry Halliwell and Kim P Wong
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLb0EW
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLc0EX
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLd0EY
VASCULAR BIOLOGY
Shb Gene Knockdown Increases the Susceptibility of SVR Endothelial
Tumor Cells to Apoptotic Stimuli In Vitro and In Vivo
Nina S Funa, Kalpana Reddy, Sulochana Bhandarkar, Elena V Kurenova,
Lily Yang, William G Cance, Michael Welsh and Jack L Arbiser
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLe0EZ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLf0Ea
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLg0Eb
WOUND HEALING
Heparin-Binding EGF-Like Growth Factor Is Induced by Disruption of
Lipid Rafts and Oxidative Stress in Keratinocytes and Participates in
the Epidermal Response to Cutaneous Wounds
Conny Mathay, Severine Giltaire, Frederic Minner, Emilie Bera, Michel
Herin and Yves Poumay
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLh0Ec
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLi0Ed
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLj0Ee
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LETTERS TO THE EDITOR
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The Localization of Label-Retaining Cells in Mouse Nails
Motonobu Nakamura and Osamu Ishikawa
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLk0Ef
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLl0Eg
Mutations in the Serum//Glucocorticoid Regulated Kinase 3 (Sgk3) Are
Responsible for the Mouse Fuzzy (fz) Hair Phenotype
Dean R Campagna, Angel O Custodio, Brendan B Antiochos, Marius V
Cirlan and Mark D Fleming
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLm0Eh
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLn0Ei
Identification of Defective Fas Function and Variation of the Perforin
Gene in an Epidermodysplasia Verruciformis Patient Lacking EVER1 and
EVER2 Mutations
Elisa Zavattaro, Barbara Azzimonti, Michele Mondini, Marco De Andrea,
Cinzia Borgogna, Valentina Dell'Oste, Massimo Ferretti, Stefania
Nicola, Giuseppe Cappellano, Adriana Carando, Giorgio Leigheb, Santo
Landolfo, Umberto Dianzani and Marisa Gariglio
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLo0Ej
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLp0Ek
IL-4 Restores Impaired Contact Hypersensitivity Response in Obese Mice
Fed a High-Fat Diet Enriched with Oleic Acid
Kazumoto Katagiri, Shoko Arakawa and Rieko Kurahashi
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLq0El
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLr0Em
Induction of p38MAPK and HSP27 Phosphorylation in Pemphigus Patient
Skin
Paula Berkowitz, Luis A Diaz, Russel P Hall and David S Rubenstein
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLs0En
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLt0Eo
Development of a Hyaluronan Targeted Contrast Reagent for the
Demarcation of Melanoma Margins In Vivo
S R Rudrabhatla, W Matthew Petroll, Christie L Mahaffey and Mark E
Mummert
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLu0Ep
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLv0Eq
Exposure to Electromagnetic Radiation Induces Characteristic Stress
Response in Human Epidermis
Rachid Ennamany, Richard Fitoussi, Katell Vie, Jerome Rambert, Lionel
De Benetti and M Djavad Mossalayi
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLw0Er
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLx0Es
Nonmonoclonal PTCH Gene Mutations in Psoralen Plus UVA-Associated
Basal Cell Carcinomas
Ellen Heitzer and Peter Wolf
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLy0Et
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnLz0Eu
SERPINE1 (PAI-1) Is a Prominent Member of the Early G0 [rarr] G1
Transition [ldquo]Wound Repair[rdquo] Transcriptome in p53 Mutant
Human Keratinocytes
Li Qi, Stephen P Higgins, Qi Lu, Rohan Samarakoon, Cynthia E
Wilkins-Port, Qunhui Ye, Craig E Higgins, Lisa Staiano-Coico and Paul
J Higgins
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL10Eh
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL20Ei
Fetuin-A: A Major Fetal Serum Protein that Promotes [ldquo]Wound
Closure[rdquo] and Scarless Healing
Xue-Qing Wang, Mark T Hayes, Margit Kempf, John F Fraser, Pei-Yun Liu,
Leila Cuttle, Lexie R Robyn Friend, Joseph A Rothnagel, Nicholas A
Saunders and Roy M Kimble
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL30Ej
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL40Ek
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CORRIGENDUM
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IL-21 Enhances Antitumor Responses without Stimulating Proliferation
of Malignant T Cells of Patients with Sezary Syndrome
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL50El
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL60Em
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ABSTRACTS
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Annual Meeting of the Society for Cutaneous Ultrastructure Research
(34th Annual Meeting of SCUR)
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL70En
PDF: http://ealerts.nature.com/cgi-bin24/DM/y/ei5Y0Xztnp0Hiw0BnL80Eo
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