Google
 
Google

World Stem Cell Summit 2010

Thursday, January 17, 2008

January 2008 CSHL Net Letter

6-Story Newsletter Template + Images
CSHL Cold Spring Harbor Laboratory Net-Letter
In This Issue: January 2008 
•   New York State Supports Expansion and Stem-cell Research at CSHL
•   Research May Lead to Improved Breast Cancer Therapies
•   Saturday DNA! Program Unravels Genetic Mysteries for Children and Adults
•   Brain Stem Cells Sensitive to Space Radiation
•   CSHL Discovery Reveals Prospect of Novel Treatment for Lung Cancer Patients
•   CSHL Scientist Recognized for Accelerating Cancer Gene Research
New York State Supports Expansion and Stem-cell Research at CSHL
New York Governor Eliot Spitzer, Empire State Development (ESD) Chairman Pat Foye, and Dr. Bruce Stillman, Cold Spring Harbor Laboratory president today announced a $2 million grant to purchase new equipment for the Hillside Campus facilities project. The grant reaffirms New York State's commitment to encouraging the growth of the local biotech industry and recognizes CSHL's long history of research discoveries that improve the human condition.

Earlier this week, the Empire State Stem Cell Board awarded a $380,933 grant to CSHL as part of New York State's new multi-year stem cell research program. The funds will support CSHL's stem cell research of cancer tumors by Patrick Paddison, Ph.D.; nervous system tumors by Linda Van Aelst, Ph.D.; mood disorders by Grigori Enikolopov, Ph.D., and attempts to regulate stem cell activity by Marja Timmermans, Ph.D.

To read more about New York State's support of CSHL research, click here.

President Stillman with Governor Spitzer
Saturday DNA! Program Unravels Genetic Mysteries for Children and Adults
Children, teens, and adults will have an opportunity to perform hands-on experiments during the Winter 2008 "Saturday DNA!" program at CSHL. The two hour laboratory and computer-based sessions are hosted by scientific staff at the Dolan DNA Learning Center (DNALC), located in the village of Cold Spring Harbor.

CSHL's cutting-edge genetic research serves as inspiration for children and adults to learn more about the genetic mysteries of life.

"Our goal is to use CSHL's cutting-edge genetic research as inspiration for children and adults to learn more about the genetic mysteries of life," said David Micklos, DNALC Executive Director.

To take part in the Saturday DNA! program, click here.

Dolan DNA Learning Center
CSHL Discovery Reveals Prospect of Novel Treatment for Lung Cancer Patients
Cancer patients usually ask what can be done after a primary tumor has already spread, or metastasized, to other organs. In many cases, they learn, little can be done. Hence the importance of a discovery by scientists at CSHL of a type of cell that regulates the transformation of small, dormant lung metastases into large, aggressive metastases – the kind that kill cancer patients.

The cells that promote the metastatic transformation are called endothelial progenitor cells, or EPCs, and are found in the bone marrow. The CSHL research team reports in the January 11 issue of Science that EPCs regulate an "angiogenic switch" – a key mechanism that causes formation of blood vessels in tumors and triggers tumor growth.

To read more about Dr. Mittal's discovery of this key mechanism that triggers tumor growth, click here.

Dr Vivek Mittal
Research May Lead to Improved Breast Cancer Therapies
By manipulating highly specific gene-regulating molecules called microRNAs, CSHL scientists report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue – cells that are widely thought to give rise to cancer.

"If certain forms of breast cancer do indeed have their origin in wayward stem cells, as we believe to be the case, then it is critical to find ways to selectively attack that tumor-initiating population," said Gregory Hannon, Ph.D., CSHL professor and Howard Hughes Medical Institute Investigator. Hannon also is head of a lab focusing on small-RNA research at CSHL and corresponding author of a paper reporting the new research, published in the latest issue of Genes and Development.

To read more about Dr. Hannon's discovery, click here.

Dr. Gregory Hannon
Brain Stem Cells Sensitive to Space Radiation
CSHL scientists recently led a team of researchers to study potential effects of space radiation on astronauts. The results of their study are revealing and will provide the foundation for ensuring the safety of crew members participating in long distance space travel. Measures to protect astronauts from health risks caused by space radiation will be important during extended missions to the moon or Mars, say researchers in a paper currently online in Experimental Neurology.

Using a mouse model designed to reveal even slight changes in brain cell populations, scientists found radiation appeared to target a type of stem cell in an area of the brain believed to be important for learning and mood control.

To read more about this Dr Enikolopov's discovery, click here.

Dr Grigori Enikolopov
CSHL Scientist Recognized for Accelerating Cancer Gene Research
Dr. Lars Zender, a senior clinical postdoctoral fellow at CSHL was recently awarded a $40,000 grant for his seminal contributions in the field of cancer biology and epigenomics. The grant, presented at the second annual "Cracking the Code with the Bear" Research Symposium, will fund Zender's ongoing cancer research.

At CSHL, Zender studies the genetics and biology of hepatocellular carcinoma, a primary cancer of the liver, and the third leading cause of cancer death worldwide. For the last four years, he has partnered with various CSHL research teams to develop a unique mouse model for liver cancer research, which enabled him to identify new tumor suppressor genes in liver cancer.

Click here to learn more about Dr. Zender's research.

Dr Lars Zender

Cold Spring Harbor Laboratory (CSHL) is a private, non-profit research and education institution at the forefront of research in cancer and molecular biology, neuroscience, plant genetics, and bioinformatics and genomics. Under the leadership of Dr. Bruce Stillman, a member of the National Academy of Sciences and a Fellow of the Royal Society (London), more than 400 scientists conduct groundbreaking research to advance the understanding and ability to diagnose and treat cancers, neurological diseases, and other causes of human suffering.

Cold Spring Harbor Laboratory is one of sixty-three institutions supported by the Cancer Centers Program of the National Cancer Institute (NCI) and has been designated as an NCI Cancer Center since 1987.

We would like to hear from you!
Contact us at pubaff@cshl.edu

 Visit www.cshl.edu to learn more today!









Never miss a thing. Make Yahoo your homepage.
Google

Any Comments ?.......

E-mail: manojhind2001us@gmail.com
Google
 

World Time