December 2007 Volume 26 Number 56, pp 7715 - 7824
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Celebrating 20 years of excellence in cancer research
Oncogene is published weekly and covers the structure and function of
oncogenes.
Visit the website at:
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Oncogene Reviews - an in-depth look into hot topics in cancer
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Each year Oncogene publishes a series of review issues that take a
closer look into the most current research and advances that are
impacting the study of cancer. Visit
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to read the latest articles from Oncogene Reviews!
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GUEST EDITORS
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Guest Editors
http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7f0Et
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INTRODUCTION
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DNA double-strand breaks: their cellular and clinical impact?
P A Jeggo and M Lobrich
http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7g0Eu
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REVIEWS
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BRCA2: a universal recombinase regulator
T Thorslund and S C West
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7h0Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7i0Ew
Non-homologous end-joining, a sticky affair
D C van Gent and M van der Burg
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7j0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7k0Ey
Activation and regulation of ATM kinase activity in response to DNA
double-strand breaks
J-H Lee and T T Paull
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7l0Ez
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7m0E1
ATM and the Mre11 complex combine to recognize and signal DNA
double-strand breaks
M F Lavin
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7n0E2
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7o0E3
Breaking down cell cycle checkpoints and DNA repair during antigen
receptor gene assembly
E Callen, M C Nussenzweig and A Nussenzweig
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7p0E4
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7q0E5
Chromatin structure and DNA double-strand break responses in cancer
progression and therapy
J A Downs
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7r0E6
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7s0E7
DNA damage signalling guards against activated oncogenes and tumour
progression
J Bartek, J Bartkova and J Lukas
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7t0E8
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7u0EA
V(D)J and immunoglobulin class switch recombinations: a paradigm to
study the regulation of DNA end-joining
P Soulas-Sprauel, P Rivera-Munoz, L Malivert, G Le Guyader, V
Abramowski, P Revy and J-P de Villartay
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7v0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7w0EC
The clinical manifestation of a defective response to DNA
double-strand breaks as exemplified by Nijmegen breakage syndrome
I Demuth and M Digweed
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7x0ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7y0EE
DNA double-strand break repair and development
E R Phillips and P J McKinnon
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi7z0EF
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi710E1
Glioblastoma multiforme: the role of DSB repair between genotype and
phenotype
U Fischer and E Meese
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi720E2
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi730E3
Targeted cancer therapies based on the inhibition of DNA strand break
repair
M J O'Connor, N M B Martin and G C M Smith
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi740E4
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh7T0Xztnp0Hjk0Bi750E5
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