December 2007 Volume 26 Number 55, pp 7607 - 7714
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What were the key developments in biomedicine during 2007? Nature
Medicine takes a look back at the year that was in our fifth Year-end
news wrap-up. Who were the movers and shakers? What were the most
influential papers of the year? What events shaped the face of
biomedical science during 2007? Visit Nature Medicine and see if you
agree with our choices.
http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0FIQ0Ee
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What is Oncogene Reviews?
Oncogene Reviews - an in-depth look into hot topics in cancer
research.
Each year Oncogene publishes a series of review issues that take a
closer look into the most current research and advances that are
impacting the study of cancer. Visit
http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Hi30Ei
to read the latest articles from Oncogene Reviews!
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REVIEW
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The field of cancer research: an indicator of present transformations
in biology
M Morange
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bito0EY
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitp0EZ
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ORIGINAL ARTICLES
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Therapeutic potential of CDK inhibitor NU2058 in androgen-independent
prostate cancer
A C Rigas, C N Robson and N J Curtin
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitq0Ea
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitr0Eb
Identification and characterization of Asef2, a guanine-nucleotide
exchange factor specific for Rac1 and Cdc42
Y Kawasaki, M Sagara, Y Shibata, M Shirouzu, S Yokoyama and T Akiyama
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bits0Ec
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitt0Ed
A novel role of Rac1 GTPase in JCV T-antigen-mediated [beta]-catenin
stabilization
R Bhattacharyya, E K Noch and K Khalili
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitu0Ee
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitv0Ef
Role of CEACAM1 isoforms in an in vivo model of mammary morphogenesis:
mutational analysis of the cytoplasmic domain of CEACAM1-4S reveals
key residues involved in lumen formation
S Yokoyama, C-J Chen, T Nguyen and J E Shively
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitw0Eg
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitx0Eh
Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer
progression through upregulation of FOXO3a activity
N Kikuno, H Shiina, S Urakami, K Kawamoto, H Hirata, Y Tanaka, R F
Place, D Pookot, S Majid, M Igawa and R Dahiya
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bity0Ei
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bitz0Ej
Pin1 is required for the Ser727 phosphorylation-dependent Stat3
activity
C Lufei, T H Koh, T Uchida and X Cao
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit10EW
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit20EX
Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular
senescence and tumor suppression
V Quereda, J Martinalbo, P Dubus, A Carnero and M Malumbres
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit30EY
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit40EZ
MMP-2 siRNA induced Fas//CD95-mediated extrinsic II apoptotic pathway
in the A549 lung adenocarcinoma cell line
C Chetty, P Bhoopathi, S S Lakka and J S Rao
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit50Ea
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit60Eb
TrkC binds to the type II TGF-[beta] receptor to suppress TGF-[beta]
signaling
W Jin, C Yun, M-K Kwak, T-A Kim and S-J Kim
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit70Ec
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0Bit80Ed
Apelin is a potent activator of tumour neoangiogenesis
S C Sorli, S Le Gonidec, B Knibiehler and Y Audigier
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0BiuA0En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0BiuB0Eo
Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates
RASSF1A-mediated microtubule interaction and M-phase cell cycle
regulation
R Rong, L Y Jiang, M S Sheikh and Y Huang
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0BiuC0Ep
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0BiuD0Eq
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SHORT COMMUNICATION
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Functional inhibition of PI3K by the [beta]GBP molecule suppresses
Ras-MAPK signalling to block cell proliferation
V Wells, J Downward and L Mallucci
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0BiuE0Er
Article: http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0BiuF0Es
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Best of 2007:
Cell Death and Differentiation brings you essential research in the
cell biology, molecular biology and biochemistry of cell death and
disease. View FREE of charge a collection of articles making an
impact on today's scientific community at
http://ealerts.nature.com/cgi-bin24/DM/y/eh3u0Xztnp0Hjk0BhRh0Eq
Includes articles from Cell Death & Differentiation's Special Issues,
Reviews and Original papers covering: neurodegenerative disorders;
mitochondrial Ca2+; caspase substrates; pyroptosome; inflammatory
caspases and inflammasomes.
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