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| Leading Edge |
| 1. | In This Issue Pages 823, 825 |
| 2. | Molecular Medicine Select Pages 827, 829 |
| Correspondence |
| 3. | ChIP-Seq Data Reveal Nucleosome Architecture of Human Promoters Pages 831-832 Christoph D. Schmid and Philipp Bucher |
| 4. | Response: Mapping Nucleosome Positions Using ChIP-Seq Data Pages 832-833 Artem Barski, Suresh Cuddapah, Kairong Cui, Tae-Young Roh, Dustin E. Schones, Zhibin Wang, Gang Wei, Iouri Chepelev and Keji Zhao |
| Preview |
| 5. | Induction of Pluripotency: From Mouse to Human Pages 834-835 Holm Zaehres and Hans R. Schöler |
| 6. | DNA Mismanagement Leads to Immune System Oversight Pages 836-838 Laurent Coscoy and David H. Raulet |
| 7. | tRNA Traffic Meets a Cell-Cycle Checkpoint Pages 838-840 Ted Weinert and Anita K. Hopper |
| 8. | Entosis: It's a Cell-Eat-Cell World Pages 840-842 Eileen White |
| 9. | Stem Cells on Patrol Pages 842-844 Robert S. Welner and Paul W. Kincade |
| 10. | cis-Regulatory Elements within the Odorant Receptor Coding Region Pages 844-846 Lillian C. Merriam and Andrew Chess |
| Review |
| 11. | Cytokinesis: Placing and Making the Final Cut Pages 847-860 Francis A. Barr and Ulrike Gruneberg |
| Articles |
| 12. | Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Pages 861-872 Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda and Shinya Yamanaka |
| 13. | Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease Pages 873-886 Yun-Gui Yang, Tomas Lindahl and Deborah E. Barnes |
| 14. | RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins Pages 887-900 Niels Mailand, Simon Bekker-Jensen, Helene Faustrup, Fredrik Melander, Jiri Bartek, Claudia Lukas and Jiri Lukas |
| 15. | RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly Pages 901-914 Michael S.Y. Huen, Robert Grant, Isaac Manke, Kay Minn, Xiaochun Yu, Michael B. Yaffe and Junjie Chen |
| 16. | Impaired tRNA Nuclear Export Links DNA Damage and Cell-Cycle Checkpoint Pages 915-926 Ata Ghavidel, Thomas Kislinger, Oxana Pogoutse, Richelle Sopko, Igor Jurisica and Andrew Emili |
| 17. | Ribosomal Protein S3: A KH Domain Subunit in NF-κB Complexes that Mediates Selective Gene Regulation Pages 927-939 Fengyi Wan, D. Eric Anderson, Robert A. Barnitz, Andrew Snow, Nicolas Bidere, Lixin Zheng, Vijay Hegde, Lloyd T. Lam, Louis M. Staudt, David Levens, Walter A. Deutsch and Michael J. Lenardo |
| 18. | Spatiotemporal Coupling of cAMP Transporter to CFTR Chloride Channel Function in the Gut Epithelia Pages 940-951 Chunying Li, Partha C. Krishnamurthy, Himabindu Penmatsa, Kevin L. Marrs, Xue Qing Wang, Manuela Zaccolo, Kees Jalink, Min Li, Deborah J. Nelson, John D. Schuetz and Anjaparavanda P. Naren |
| 19. | Force-Induced Bidirectional Stepping of Cytoplasmic Dynein Pages 952-965 Arne Gennerich, Andrew P. Carter, Samara L. Reck-Peterson and Ronald D. Vale |
| 20. | A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion Pages 966-979 Michael Overholtzer, Arnaud A. Mailleux, Ghassan Mouneimne, Guillaume Normand, Stuart J. Schnitt, Randall W. King, Edmund S. Cibas and Joan S. Brugge |
| 21. | Integrating Patterning Signals: Wnt/GSK3 Regulates the Duration of the BMP/Smad1 Signal Pages 980-993 Luis C. Fuentealba, Edward Eivers, Atsushi Ikeda, Cecilia Hurtado, Hiroki Kuroda, Edgar M. Pera and Edward M. De Robertis |
| 22. | Immunosurveillance by Hematopoietic Progenitor Cells Trafficking through Blood, Lymph, and Peripheral Tissues Pages 994-1008 Steffen Massberg, Patrick Schaerli, Irina Knezevic-Maramica, Maria Köllnberger, Noah Tubo, E. Ashley Moseman, Ines V. Huff, Tobias Junt, Amy J. Wagers, Irina B. Mazo and Ulrich H. von Andrian |
| 23. | Prominent Roles for Odorant Receptor Coding Sequences in Allelic Exclusion Pages 1009-1017 Minh Q. Nguyen, Zhishang Zhou, Carolyn A. Marks, Nicholas J.P. Ryba and Leonardo Belluscio |
| SnapShot |
| 24. | SnapShot: EGFR Signaling Pathway Pages 1018.e1-1018.e2 Yosef Yarden and Ben-Zion Shilo |
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