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World Stem Cell Summit 2010

Wednesday, November 28, 2007

Keyword News: [stem cell]

Yahoo! Alerts Yahoo! News - My Alerts - Edit Alert
Wednesday, November 28, 2007 10:31 PM PST

Audit Ordered for California Stem Cell Agency
Wired News Wed, 28 Nov 2007 3:21 PM PST
The California state controller has ordered an audit of the state's stem cell research-funding institute, citing accusations of conflict of interest.

Stem-cell Therapies For Brain More Complicated Than Thought
Science Daily Wed, 28 Nov 2007 8:04 PM PST
Stem cell therapies for the brain could be much more complicated than previously thought. Scientists report that adult stem cells produced in the brain are pre-programmed to make only certain kinds of connections- - making it impossible for a neural stem cell originating in the brain to be transplanted to the spinal cord, for instance, to take over functions for damaged cells.

Paralyzed Mishawaka Grad Has New Hope After Stem Cell Transplant
22 WSBT South Bend Wed, 28 Nov 2007 1:34 PM PST
(WSBT) A woman from Mishawaka had a stem cell transplant and is regaining some use of her legs. Many people remember Sarah Schools Clay as a star basketball player for Mishawaka High School. In 2001, she was in an ATV accident that paralyzed her from the waist down. Now, she's learning to walk again.

Chennai gets stem cell research, banking centre
IANS via Yahoo! India News Wed, 28 Nov 2007 5:17 AM PST
Chennai, Nov 28 (IANS) Leading US stem cell research firm LifeCell has helped set up a Rs 50-million cord blood stem cell banking and research facility at Sri Ramachandra Medical University here to help stem cell and bone marrow transplants for haematological and oncological disorder patients.

Brain stem-cell therapies more complicated than thought
News-Medical-Net Wed, 28 Nov 2007 1:15 PM PST
An MIT research team's latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought.

Stem-Cell Therapies For Brain More Complicated Than Thought
Medical News Today Wed, 28 Nov 2007 7:18 AM PST
An MIT research team's latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought.In a study published in the Public Library of Science (PloS) Biology on Nov. [click link for full article]

Controller will audit stem-cell institute
San Jose Mercury News Wed, 28 Nov 2007 2:28 AM PST
California Controller John Chiang on Tuesday joined a consumer group in requesting an investigation of a board member of the state's $3 billion stem-cell institute and said he will audit the institute to ensure it is spending its money appropriately.

Study reports evidence of mature heart cell potential in embryonic stem cells
ANI via Yahoo! India News Tue, 27 Nov 2007 10:51 PM PST
Washington, Nov 28 (ANI): A new study has reported the first functional evidence that heart cells derived from human embryonic stem cells exhibit one of the most critical properties of mature adult heart cells, an important biological process called excitation-contraction coupling. The study, led by Ronald Li, an associate professor of cell biology and human anatomy at UC Davis School of ...

Stem cell findings change debate
Daily Princetonian Tue, 27 Nov 2007 11:56 PM PST
Though the issue of embryonic stem cell research has been one of the most contentious political topics in recent years, a landmark discovery may finally bring an end to the debate.




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Mol. Biol. Cell MBC In Press for 28 Nov 2007

Molecular Biology of the Cell

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Mol. Biol. Cell Online MBC In Press Alert

New Molecular Biology of the Cell MBC In Press articles have been made available
(for the period 21 Nov 2007 to 28 Nov 2007):


Articles
KNL1 and the CENP-H/I/K Complex Coordinately Direct Kinetochore Assembly in Vertebrates
Iain M. Cheeseman, Tetsuya Hori, Tatsuo Fukagawa, and Arshad Desai
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-10-1051
http://www.molbiolcell.org/cgi/content/abstract/E07-10-1051v1

B-RAF Regulation of Rnd3 Participates in Actin Cytoskeletal and Focal Adhesion Organization
R. Matthew Klein, Laurie S. Spofford, Ethan V. Abel, Arisa Ortiz, and Andrew E. Aplin
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-09-0895
http://www.molbiolcell.org/cgi/content/abstract/E07-09-0895v1

Myosin Transducer Mutations Differentially Affect Motor Function, Myofibril Structure, and the Performance of Skeletal and Cardiac Muscles
Anthony Cammarato, Corey M. Dambacher, Aileen F. Knowles, William A. Kronert, Rolf Bodmer, Karen Ocorr, and Sanford I. Bernstein
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-09-0890
http://www.molbiolcell.org/cgi/content/abstract/E07-09-0890v1

The Golgi Protein GM130 Regulates Centrosome Morphology and Function
Andrew Kodani and Christine Sütterlin
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-08-0847
http://www.molbiolcell.org/cgi/content/abstract/E07-08-0847v1

Hsp90 Stabilizes the PMR1 mRNA Endonuclease to Degradation by the 26S Proteasome
Yong Peng, Xiaoqiang Liu, and Daniel R. Schoenberg
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-08-0774
http://www.molbiolcell.org/cgi/content/abstract/E07-08-0774v1

Transmembrane Domain Interactions Control Biological Functions Neuropilin-1
Lise Roth, Cécile Nasarre, Sylvie Dirrig-Grosch, Dominique Aunis, Gérard Crémel, Pierre Hubert, and Dominique Bagnard
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-06-0625
http://www.molbiolcell.org/cgi/content/abstract/E07-06-0625v1

PP2A Regulates HDAC4 Nuclear Import
Gabriela Paroni, Nadia Cernotta, Claudio Dello Russo, Paola Gallinari, Michele Pallaoro, Carmela Foti, Fabio Talamo, Laura Orsatti, Christian Steinkühler, and Claudio Brancolini
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-06-0623
http://www.molbiolcell.org/cgi/content/abstract/E07-06-0623v1

RFCCtf18 and the Swi1-Swi3 Complex Function in Separate and Redundant Pathways Required for the Stabilization of Replication Forks to Facilitate Sister Chromatid Cohesion in Schizosaccharomyces pombe
Alison B. Ansbach, Chiaki Noguchi, Ian W. Klansek, Mike Heidlebaugh, Toru M. Nakamura, and Eishi Noguchi
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-06-0618
http://www.molbiolcell.org/cgi/content/abstract/E07-06-0618v1

Sequestration of Mutated {alpha}1-Antitrypsin Into Inclusion Bodies Is a Cell Protective Mechanism to Maintain Endoplasmic Reticulum Function
Susana Granell, Giovanna Baldini, Sameer Mohammad, Vanessa Nicolin, Paola Narducci, Brian Storrie, and Giulia Baldini
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-06-0587
http://www.molbiolcell.org/cgi/content/abstract/E07-06-0587v1

Conversion of a Replication Origin to a Silencer through a Pathway Shared by a Forkhead Transcription Factor and an S-Phase Cyclin
Laurieann Casey, Erin E. Patterson, Ulrika Müller, and Catherine A. Fox
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E07-04-0323
http://www.molbiolcell.org/cgi/content/abstract/E07-04-0323v1

Paxillin Phosphorylation Controls Invadopodia/Podosomes Spatiotemporal Organization
Cédric Badowski, Géraldine Pawlak, Alexei Grichine, Anne Chabadel, Christiane Oddou, Pierre Jurdic, Martin Pfaff, Corinne Albigès-Rizo, and Marc R. Block
Mol. Biol. Cell published 28 November 2007, 10.1091/mbc.E06-01-0088
http://www.molbiolcell.org/cgi/content/abstract/E06-01-0088v1


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ABC Science Updates, November 29, 2007

==== ABC Science Updates, November 29, 2007 ==================

Science Updates is a weekly email alert about recent online science coverage and upcoming TV and radio science programs from the Australian Broadcasting Corporation (ABC)

==== NEW ON ABC SCIENCE ONLINE ==== http://www.abc.net.au/science ====

ACE DAY JOBS - Molecular Chemist
Deanna looks at how to mimic natural systems such as photosynthesis to provide a viable source of renewable energy that will power the world.
http://www.abc.net.au/acedayjobs/cooljobs/profiles/s2102676.htm

FACT BUSTERS - Does milk make mucus worse?
All is revealed at:
http://abc.net.au/health/talkinghealth/factbuster/stories/2007/11/28/2102703.htm


SCIENCE PODCASTS
If it's science and it was on the radio, chances are you can download it as a podcast! You can browse or subscribe to science on everything from Radio National to triple j right here:
http://www.abc.net.au/science/programs/podcast.htm


==== TOP NEWS STORIES FROM NEWS IN SCIENCE =====

GM CANOLA GO-AHEAD SPARKS DEBATE (News in Science 29/11/07)
The decision by two state governments to end a ban on the planting of genetically modified canola has exposed a lack of Australian research into its harms and benefits, critics say.
http://www.abc.net.au/science/articles/2007/11/29/2104266.htm

AMPUTEE 'FEELS' LIMB IN CHEST (Health & Medical, 27/11/07)
Amputees could 'feel' their lost arms and hands after scientists reconnected the nerves to their chests, according to a report released today.
http://www.abc.net.au/science/articles/2007/11/27/2102210.htm

FOOD MILES CAN MISLEAD (Environment & Nature, 28/11/07)
The average Australian basket of food has travelled over 70,000 kilometres from producer to consumer, suggests the first study of its kind.
http://www.abc.net.au/science/articles/2007/11/28/2103395.htm

TEEN GALAXIES HINT OF EARLY MILKY WAY (Space & Astronomy, 28/11/07)
Astronomers have spotted the young building blocks of galaxies similar to the Milky Way for the first time, giving a tantalising glimpse of how our stellar backyard may have formed.
http://www.abc.net.au/science/articles/2007/11/28/2103608.htm

JADE EARRINGS OPEN DOOR ON ANCIENT TRADE (Ancient Worlds, 20/11/07)
Taiwan was at the centre of a one of the most extensive sea-based trade networks in the prehistoric world, new research shows.
http://www.abc.net.au/science/articles/2007/11/20/2095026.htm

VENUS FLYTRAP INSPIRES SNAPPING LENS (Innovation & Technology, 27/11/07)
A microscopic lens, inspired by a Venus flytrap's ability to trap insects in a split second, can pop instantly between convex and concave when triggered, scientists say.
http://www.abc.net.au/science/articles/2007/11/27/2102439.htm

MORE NEWS IN SCIENCE - updated daily
http://www.abc.net.au/science/news/

==== IN THE SKY THIS WEEK ====
The Last Quarter Moon is Saturday December 1. Jupiter is the brightest object above the western horizon during twilight, and will soon disappear from view. In the morning sky red Mars can be easily seen as the brightest object in the northern sky, underneath the distinctive constellation of Orion. Mars forms a broad triangle with the red stars Alderbaran and Betelguese. Saturn and brilliant white Venus can be easily seen above the eastern horizon in the early morning. On Sunday December 2 the waning Moon is near Saturn, and on Thursday December 6 the crescent Moon is near Venus.

http://home.mira.net/~reynella/skywatch/ssky.htm

==== ABC HEALTH & WELLBEING == http://www.abc.net.au/health/ =====

THE PULSE: 10000 steps and counting
Walking with a pedometer will help you lose weight and lower blood pressure, say US researchers.
http://abc.net.au/health/thepulse/stories/2007/11/29/2104899.htm

Health Updates provides the latest ABC Health information online. You can join at: http://www.abc.net.au/health/subscribe/


==== NEW RADIO AND TV SCIENCE TRANSCRIPTS NOW ONLINE ====

STEM CELL BREAKTHROUGH MAY DEFUSE ETHICAL QUESTIONS (Lateline: 21/11/2007) http://www.abc.net.au/lateline/content/2007/s2097528.htm


LESLEY HUGHES (In Conversation: 22/11/2007)

http://www.abc.net.au/rn/inconversation/stories/2007/2089478.htm


BRAIN SURGERY ON THE WIRELESS! (PART 1 OF 2) (All In The Mind: 24/11/2007)

http://www.abc.net.au/rn/allinthemind/stories/2007/2094756.htm

MAX PERUTZ - FATHER OF MOLECULAR BIOLOGY (Science Show: 24/11/2007)

http://www.abc.net.au/rn/scienceshow/stories/2007/2098178.htm


HOW THE EAR CONVERTS SOUND TO NERVE IMPULSES - HERMANN VON HELMHOLTZ 1857 (Science Show: 24/11/2007)

http://www.abc.net.au/rn/scienceshow/stories/2007/2098185.htm


QUEEN BEES AFFECT WORKERS' BRAINS (Science Show: 24/11/2007)

http://www.abc.net.au/rn/scienceshow/stories/2007/2098171.htm


EXPLOSIVES HELP REVEAL TERROR SUSPECTS (Science Show: 24/11/2007)

http://www.abc.net.au/rn/scienceshow/stories/2007/2095827.htm


===== COMING UP - ABC RADIO ===========
http://www.abc.net.au/science/programs/
Podcasts and downloads
http://www.abc.net.au/science/programs/podcast.htm

SCIENCE SHOW - Survival versus the enlightenment
Saturday 1 December, 12.05pm & Monday 3 December, 7.05pm RN
The immense global threats we face from climate change and ecological collapse will require single-minded, ruthless responses. Yet western civilisation - and systems of government in various parts of the world - flourish as a result of dissent and pluralism. This clash of intent, authoritarianism versus tolerance in the face of emergency is Lord May's theme in this Science Show extract from his Lowy Lecture. Professor Robert May is a former Chief scientist (UK) and only the second Australian after Howard Florey to be President of the Royal Society of London.
http://www.abc.net.au/rn/scienceshow/

ALL IN THE MIND - Brain Surgery on the airwaves! - One year on [Part 2]
Saturday 1 December, 1.05pm, & Monday 3 December, 1.05pm RN
Last year All in the Mind first took you on an audiophonic adventure into the operating theatre and into the brain of Kia, as the tendrils of an arteriovenous malformation (AVM) were extracted from her frontal lobes. 11 months after the surgery, meet Kia again for an update on life post-op. Surviving major brain surgery has been the easy bit. Navigating the welfare system as she recovers has been a mind-field, literally.
http://www.abc.net.au/rn/allinthemind/

THE PHILOSOPHER'S ZONE - What's social (and what's just) about social justice?
Saturday 1 December, 1.30pm, & Monday 3 December, 1.35pm RN
With a new government running the country, can we hope for more social justice, or will there be less of it? This week we ask what social justice is and whether we really need more of it.
http://www.abc.net.au/rn/philosopherszone/default.htm

OCKHAM'S RAZOR - Language and the human story
Sunday 2 December, 8.45am RN
Dr David Rose from the Department of Linguistics at Sydney University delves into a question that has puzzled humanity for a very long time - where did we all come from? From his research he has found that there are many patterns of words that are universal across languages. How has the spoken word been replicated over hundreds of generations so that the patterns are still recognisable in countries as remote from each other as Australia and Europe?
http://www.abc.net.au/rn/ockhamsrazor/

INNOVATIONS
Sunday 2 December (0830hrs UT), Monday 3 December (1330 & 1705hrs UT), Wednesday 5 December (0430hrs UT), Radio Australia
Sing to your computer to find that music; Australian solar technology to revolutionise clean electricity and, straw the new green building product finding global markets.

http://www.abc.net.au/ra/innovations/

HEALTH REPORT - The obesity epidemic
Monday 3 December, 8.30am and 8.05pm RN
A researcher in the United States claims that the reason for the obesity epidemic is more than just the calories we eat and the lack of exercise. It's a substance that food manufacturers are widely using. This program is a repeat and was first broadcast on 9th July, 2007.
http://www.abc.net.au/rn/healthreport/

IN CONVERSATION - Where to now?
Thursday 6 December, 7.35pm RN
The resources boom will not bust - it will plateau. But Australia will have to prepare itself for this intense, long-term demand on its skills and ability to innovate. A new government offers a chance to start again. Dr Robin Batterham of Rio Tinto, now President of the Australian Academy of Technological Sciences and Engineering, looks to the future. He sees opportunities - but also, formidable challenges. Coasting along as usual won't work.
http://www.abc.net.au/rn/inconversation/

==== COMING UP - ABC TV ===========
http://www.abc.net.au/science/programs/

TAKE ON TECHNOLOGY - Cubby Houses (For kids)
Friday 30 November, 10:00am
Monster puppets, Dodly and Flyn, take a fascinating look at designing technology to meet particular needs. This 12-part series adopts an investigative approach to help children recognise and understand the use of technology around them.

AUSTRALIA EYE OF THE STORM - El Nino
Friday 30 November 11:05am
Looks at how our diverse wildlife has adapted to the huge swings in climate - the heartbreaking droughts and fires, which El Nino brings.
http://www.abc.net.au/storm/

FORCE OF NATURE - Campbell's Final Run
Saturday 1 December 1pm
Stories that reveal the raw power of nature testing our primal fears.

BINDI THE JUNGLE GIRL - Poached Eggs (For kids)
Sunday 2 December, 6:55am
From her tree-house perched high in the jungle, Bindi Irwin will take us to every corner of the globe, to meet cute to not-so-cute animals and learn how all animals need to be protected.
http://abc.net.au/children/bindi/

RAMPANT: How A City Stopped A Plague
Monday 3 December, 8:30pm
The story of AIDS in Australia, and how our response to the disease - so radically different from that in the USA and other countries with conservative governments - made us world leaders in controlling the virus, which had the potential to become a plague.

SINGER: A Dangerous Mind
Tuesday 4 December, 11am
At a time when medical science can prolong life almost indefinitely, Dr Peter Singer's radical views on matters such as animal rights, abortion and infanticide have seen him labelled both a visionary and a Nazi sympathiser.

SURFING SCIENTIST ON ROLLERCOASTER (For kids)
Tuesday 4 December, between 5-6pm
Catch Ruben Meerman each Tuesday afternoon as he gives Rollercoaster's host Elliot a dose of science. Apparently you can teach young hosts old tricks.
http://www

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[StemCellInformation] Google News Alert for: STEM CELL INFORMATION-Monday, November 26, 2007 10:20:46

Google News Alert for: STEM CELL INFORMATION

Monday, November 26, 2007 10:20:46 PM

Stem cell clinic closed
The Nation Newspaper - Bridgetown,St. Michael,Barbados
The BBC documentary aired last December 12 and was re-screened on BBC World News on December 13, claimed that stem cells in the city of Kharkiv, ...
See all stories on this topic

Pluristem's Reverse Stock Split Effective Today
WELT ONLINE - Germany
About Pluristem Pluristem Therapeutics, Inc. is a Company dedicated to the commercialization of non-personalized (allogeneic) stem cell therapy products for ...
See all stories on this topic

Health/Science Calendar
Boston Globe - United States
Stem cell century The Harvard Stem Cell Institute and Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard Law School will host ...
See all stories on this topic

End of the divide
Guardian Unlimited - UK
First, biologists have long been persuaded that careful studies of how embryonic stem cells transform themselves into organs and sophisticated tissue will ...
See all stories on this topic

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[StemCellInformation] Google News Alert for: stem cells

Google News Alert for: stem cells

Monday, November 26, 2007 9:23:09 AM   

Hermitage parents plan trip to Thailand for stem-cell
Youngstown Vindicator - Youngstown,OH,USA
They plan to take her to Thailand in January for an experimental adult stem cell procedure that they hope will help strengthen her heart, and also help her ...
See all stories on this topic

NW: Kyoto U. team turns skin into stem cells
Therapeutics Daily (subscription) (press release) - Newtown,PA,USA
A team of Kyoto University researchers has succeeded in cultivating stem cells from human skin, clearing a major hurdle in growing transplant tissue from a ...
See all stories on this topic

International Stem Cell Corporation CEO Issues Statement on De ...
Business Wire (press release) - San Francisco,CA,USA
Mr Krstich's message further noted that unlike the de-differentiation process, the stem cell lines produced by ISCO's Parthenogenesis process do not employ ...
See all stories on this topic

Google Blogs Alert for: stem cells

If Embryonic Stem Cell Research is SO Great...
By mike volpe(mike volpe)
Bush isn't against stem cell research and in fact he isn't against any form of stem cell research at all, even the controversial embryonic stem cell research. Bush isn't even against government funding for all embryonic stem cell ...
Proprietor Nation - http://proprietornation.blogspot.com/

This Season's Hottest Gift - Stem Cells
By aristheologis
Two independent teams, one from Japan and the other from Wisconsin, have shown that, "they turned human skin cells into what appear to be embryonic stem cells without having to make or destroy an embryo." This accomplishment is reason ...
Intellitech: Chronicling Innovation - http://intellitech.wordpress.com

QBI Neuroscience Seminar - Physical exercise stimulates resident ...
By UQ Events
Speaker: Dr Daniel Blackmore, Queensland Brain Institute Title: Physical exercise stimulates resident stem cells & augments the regenerative capacity of the ageing brain All welcome.
UQ Events - http://www.uq.edu.au/events/

Embryonic Stem Cells From Skin: Making Old Cells Young
This video was placed by the stem cell clinic Cellmedicine (www.cellmedicine.com) describing the recent paper that makes adult skin cells into embryonic stem cells. The video available at http://www.youtube.com/watch?v=_RLlUdJLy74 ...
Digg / upcoming - http://digg.com/

Stem cell breakthrough by PZ Myers, Pharyngula
A recent discovery in stem cell research is no minor event: researchers have figured out how to reprogram adult cells into a state that is nearly indistinguishable from that of embryonic, pluripotent stem cells. ...
RichardDawkins.net : The Latest Updates - http://richarddawkins.net/

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[StemCellInformation] Germany Doubling Stem Cell Funding

Germany Doubling Stem Cell Funding

 

11/28/2007

It is being reported by the German government that they will be doubling the amount of yearly funding that they provide for stem cell research

It is being reported that Germany will be doubling their funding for stem cell research.

The current allocation of five million euros (7.4 million dollars) will be raised to to just under 10 million euros, Annette Schavan told the weekly Focus magazine in an interview.

"From now on we are going to double the annual funding total for adult cell recoding techniques, in order to push forward advances in this area," she said.

"Over the next few years Germany must be a motor in adult stem cell research so that we can expand on the results already obtained," she added.

This move by the German government to double funding for stem cell research has not come without its critics, with many people feeling that any research involving the use of stem cells is unethical and should not be federally funded.

Those critics should be a tad more open to the idea of stem cell research, as recent results have proven that stem cells can be extracted from human skin thus not from a live human or animal embryo.

"First, there has been a debate over the stem cells research," said Junying Yu, Ph.D. from the University of Wisconsin. "Because extraction of stem cells by the existing methods leads to destruction of embryos and closing of human embryos has also resulted in ethnical debate. If we can transform the human skin cells into stem cells, we avoid this type of debate. Second, if the cells from a patient can be reprogrammed into stem cells similar to embryonic stem cells made through the cloning techniques, tissue and or organs can be cultured and used for transplantation in the patient. Third, the stem cells made using our technique can be used to test and precisely predict the effect of drugs on the patients because of its unique genetic fingerprint."

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[StemCells] Stem Cells to Boost Memory

Stem Cells May Reverse Brain Injury and Restore Memory
By Aaron Elias
Memories help construct lives and life experiences—without them,
living life would be nearly impossible. Alzheimer's and Parkinson's
diseases are debilitating illnesses capable of ruining victims' lives
and inflicting pain and sadness on their families. Recent findings at
UC Irvine show that the use of stem cells can reverse memory loss
after brain injuries and diseases, such as Alzheimer's.

"This study can very well benefit people with diseases such as
Alzheimer's and Parkinson's, as well as physical brain injuries and
neuron loss, if it becomes transferable to humans," said Debbie
Morisette, a stereologist working on the study. "But as of right now,
we don't think it will benefit cancer patients, though it is not
impossible it could be used as therapy."

The stem cells used in the research are not embryonic, meaning that
they do not come from unborn fetuses. Instead, the stem cells come
from fully developed organs, such as those donated by people who died
in car accidents.

Embryonic stem cells are much like lumps of clay waiting to be
molded. While embryonic stem cells can develop into anything, adult
stem cells have already begun to move down a particular pathway and
can only develop into certain types of cells—in this case, neural
(brain) stem cells. These adult stem cells create little to no
controversy and, as a result, scientists have encountered little
ethical protest, allowing them to focus on their study.

"It depends on funding and progress," said Matthew Blurton-Jones, a
UCI neuroscientist heading the research. "But realistically, I'd say
it would take about five to 10 years for this research to become
transferable to humans."

Scientists used a carefully-bred and maintained group of mice to test
the research. They destroyed neurons in the hippocampus to create
memory loss and recorded the mice's performance on a series of memory-
related tests.

The mice were then injected with neural stem cells and retested. In
most cases, the mice tested after stem cell injection scored much
higher than they did with memory impairment, almost as high as
healthy mice.

Contrary to initial inference, the number of neurons did not increase
very much after the injections, only by about 7 percent. It turns out
that the rest of the stem cells turned into memory-supporting cells,
such as astrocytes, which promote neural survival and connectivity,
and oligodendrocytes, which insulate neural connections. A popular
hypothesis is that these supporting cells help create stronger and
newer connections between existing neurons.

The scientists may have high hopes for this new research, but they
are by no means disregarding the possible drawbacks.

"We have a lot left to study," explained Misashi Kitazawa, a
toxicologist working on the study. "Stem cells multiply and rebuild,
so there are many possibilities. They may create tumors, they may
not."

The research is very costly, but it is not the cost of the stem cells
that weighs heaviest on the budget.

"The research as a whole has probably cost somewhere between $500,000
to $750,000," Blurton-Jones said. "Each tiny vial of stem cells costs
around $300 to $400, but the animal costs and maintaining of the mice
are the most expensive."

Trita Yamasaki, another head scientist working on the study, is in
control of breeding the mice to produce the desired characteristics.
Yamasaki is also one of the scientists who spearheaded the study
along with UCI professor of neurobiology and behavior Frank LaFerla,
but neither could be reached for comment.

Even non-medical students around campus seem to support the research.

"I'm all for it," said Saman Mohseni, a second-year psychology
major. "With the right amount of technology, anything can happen."
While the research is not 100 percent guaranteed to succeed, others
are hopeful that humans will one day be able to use it.

"[This is] some very promising research," said Diego Kapelusznik, a
second-year political science major. "If it has even a slight chance
that it might cure diseases like Alzheimer's, then it's worth a try."
With the potential advent of neural stem cells available as a memory-
enhancing drug, brain injuries and diseases will be easier to cope
with for both the victim and their loved ones.

Neural stem cell research provides some very promising possibilities,
but it will be quite a while before we see it enter the realm of the
human brain.

http://www.newuniversity.org/checkDB.php?id=6279

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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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