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EMBO Reports Table of Contents May 2008, Volume 9, Number 5, pp 401-491

EMBO REPORTS TABLE OF CONTENTS

May 2008 Volume 9 Number 5, pp 401-491
(c) Copyright 2008 by the European Molecular Biology Organization
Now available at http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60rc0Eo


Visit EMBO reports online to browse the content of the current
issue, including Editorial, Science & society, Reviews and
Scientific reports.

To purchase a subscription, please visit
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60rd0Ep

*********************************************************************

Contents: Volume 9, Number 5 (May 2008)

---------------------
EDITORIAL
---------------------


Paralysed by perfection.
Frank Gannon
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttO0EY

---------------------
SCIENCE AND SOCIETY
---------------------

CORRESPONDENCE

Comment in response to `A question of method' by Samia A. Hurst & Alex Mauron.
Ragnar Rylander
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttP0EZ


Response by Samia A. Hurst & Alex Mauron.
Samia A Hurst & Alex Mauron
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttQ0Ea

VIEWPOINTS

An open challenge. Open access and the challenges for scientific publishing.
Xavier Bosch
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttR0Eb


The grand impact of the Gates Foundation. Sixty billion dollars and one famous person can affect the spending and research focus of public agencies.
Kirstin RW Matthews & Vivian Ho
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttS0Ec

ANALYSES

We are what we eat. The link between diet, evolution and non-genetic inheritance.
Philip Hunter
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttT0Ed


Paths to acceptance. The advancement of scientific knowledge is an uphill struggle against `accepted wisdom'.
Howard Wolinsky
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttU0Ee

---------------------
REVIEWS
---------------------

MEETING REPORTS

To the centre of the volcano. Workshop on the Mechanisms of Nucleocytoplasmic Transport.
Maarten Fornerod & Paul R. Clarke
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttV0Ef


Science amongst the vines. Meeting on Signalling Systems.
Stuart M Pitson, Gregory J Goodall & Mark A Guthridge
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttW0Eg

REVIEWS

PeptideAtlas: a resource for target selection for emerging targeted proteomics workflows.
Eric W Deutsch, Henry Lam & Ruedi Aebersold
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttX0Eh
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttY0Ei


No single way to understand singlet oxygen signalling in plants.
Chanhong Kim, Rasa Meskauskiene, Klaus Apel & Christophe Laloi
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60BttZ0Ej
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Btta0Eq

---------------------
SCIENTIFIC REPORTS
---------------------


`Insulator bodies' are aggregates of proteins but not of insulators.
Anton Golovnin, Larisa Melnikova, Ilya Volkov, Margarita Kostuchenko, Alexander V Galkin & Pavel Georgiev
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttb0Er
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttc0Es


NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA.
Collynn F Woeller, Martina Gaspari, Olaf Isken & Lynne E Maquat
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttd0Et
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Btte0Eu


The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5.
Matthieu Lacroix, Selma El Messaoudi, Geneviève Rodier, Aphonse Le Cam, Claude Sardet & Eric Fabbrizio
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttf0Ev
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttg0Ew


Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase [lambda].
Katarzyna Bebenek, Miguel Garcia-Diaz, Meredith C Foley, Lars C Pedersen, Tamar Schlick & Thomas A Kunkel
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Btth0Ex
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Btti0Ey


Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos.
Brian Stramer, Mark Winfield, Tanya Shaw, Thomas H Millard, Sarah Woolner & Paul Martin
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttj0Ez
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttk0E1


Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits.
Chang-Xi Bai, Aurélie Giamarchi, Lise Rodat-Despoix, Francoise Padilla, Tamyra Downs, Leonidas Tsiokas & Patrick Delmas
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttl0E2
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttm0E3


Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis.
Beixue Gao, Sang-Myeong Lee, An Chen, Jinping Zhang, Donna D Zhang, Krishnaswamy Kannan, Robert A Ortmann & Deyu Fang
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttn0E4
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Btto0E5


NEDD8 acts as a `molecular switch' defining the functional selectivity of VHL.
Ryan C Russell & Michael Ohh
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttp0E6
http://ealerts.nature.com/cgi-bin24/DM/y/ekaT0Xztnp0Hh60Bttq0E7


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For more information, see each journal's latest table of contents:

Nature Volume 453 Number 7191 pp 1-132
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BuAI0E2

Nature Physics Volume 4 Number 4 pp 257-336
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BruN0Ev

Nature Nanotechnology Volume 3 Number 4 pp 179-233
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BsRv0E2

Nature Photonics Volume 2 Number 4 pp 199-256
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BruO0Ew

Nature Materials Volume 7 Number 4 pp 255-339
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BrIt0Ep

======================================================================

Nature Photonics 1st anniversary highlights

January 2008 marked the first anniversary of the launch of
Nature Photonics. To celebrate, the editors have put together
their highlights from the first 12 issues. The selection,
which is available free until 31st May 2008, reflects the
diversity of Nature Photonics content – in style of article
and in the topics covered. We hope that you will enjoy
browsing through the list, and join us in looking forward to
an informative second year.

A look back at our first year.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bl5u0EQ

======================================================================

-------------------------------
News
-------------------------------

If you go down to the woods today...
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt270ET

Programs promise to end PDF paper-chase
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3B0Ef

-------------------------------
News in brief
-------------------------------

A lift for Europe's satellites
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3E0Ei

-------------------------------
News feature
-------------------------------

Physics: Quantum all the way
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3M0Eq

-------------------------------
Books and arts
-------------------------------

Exhibition: Measure for measure
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3X0E2

-------------------------------
Essay
-------------------------------

Lifting the fog from the north
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3c0EE

-------------------------------
News and views
-------------------------------

Electronics: The fourth element
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3e0EG

Quantum physics: The squeeze goes on
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3g0EI

Astrophysics: Rays from the dark
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3j0EL

-------------------------------
Obituaries
-------------------------------

John Wheeler (1911–2008)
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3k0EM

-------------------------------
Letters
-------------------------------

Superconductivity at 43 K in an iron-based layered compound LaO1-xFxFeAs
Hiroki Takahashi et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BuAJ0E3

The sculpting of Jupiter's gossamer rings by its shadow
Douglas P. Hamilton & Harald Kruger
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3r0ET

Phase-slip-induced dissipation in an atomic Bose–Hubbard system
D. McKay, M. White, M. Pasienski & B. DeMarco
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3t0EV

The missing memristor found
Dmitri B. Strukov, Gregory S. Snider, Duncan R. Stewart
& R. Stanley Williams
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt3v0EX

Towards fault-tolerant quantum computing with trapped ions
Jan Benhelm, Gerhard Kirchmair, Christian F. Roos & Rainer Blatt
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BuAK0E4

Process tomography of quantum memory in a Josephson-phase qubit
coupled to a two-level state
Matthew Neeley et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BuAL0E5

Thermodynamic properties of a spin-1/2 spin-liquid state in a kappa-type
organic salt
Satoshi Yamashita et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BuAM0E6

Mass production and dynamic imaging of fluorescent nanodiamonds
Yi-Ren Chang et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt8j0EQ

Omnidirectional absorption in nanostructured metal surfaces
T. V. Teperik
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BtxQ0E4

-------------------------------
Articles
-------------------------------

Discovery of an excited pair state in superfluid 3He
J. P. Davis, J. Pollanen, H. Choi, J. A. Sauls & W. P. Halperin
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BuAN0E7

Electric-field control of local ferromagnetism using a magnetoelectric
multiferroic
Ying-Hao Chu et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0Bt870EZ

Electronic structures of interfacial states formed at polymeric
semiconductor heterojunctions
Ya-shih Huang et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc20Xztnp0Hjm0BuAA0Et

=====================================================================

Visit the Nature China website today!
From biotechnology to neuroscience, physics to clinical medicine, this
one-stop web portal, provides you with weekly highlights of leading
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For more information, see each journal's latest table of contents:

Nature Volume 453 Number 7191 pp 1-132
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8e0EN

Nature Materials Volume 7 No 5 pp 341-417
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8f0EO

Nature Nanotechnology Volume 3 Number 4 pp 179-233
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bsww0Eh

Nature Physics Volume 4 Number 4 pp 257-336
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BruN0Ex

Nature Biotechnology Volume 26 No 4 pp 375-442
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8g0EP

Nature Photonics Volume 2 No 5 pp 257-324
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8h0EQ

=====================================================================

Nature Materials Focus on Polymers

This focus examines the role of academia–industry
collaborations in the theoretical design and
understanding of these materials, how such
collaborations can improve and shorten development
routes to products, and the benefits they can bring
to the academic partner.

We are delighted to acknowledge financial support from
DuPont, which has enabled us to offer the focus and
additional content from our archive online for free.

View the focus online:
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BrvU0E6

=====================================================================

------------------------------
Editorial
------------------------------

SUPERCONDUCTORS REDUX
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtLu0Ex

------------------------------
News
------------------------------

BUCKYBALLS GIVE FLASH A BOOST
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtL20Eq

ARSENIC HEATS UP IRON SUPERCONDUCTORS
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtL30Er

RAINDROPS ON ROSES
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtvY0ED

------------------------------
Commentary
------------------------------

EUROPE'S RESEARCH SYSTEM MUST CHANGE
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtMK0EI

MAKING THE GRADE
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt3T0Ez

-------------------------------
Books and Arts
-------------------------------

EXHIBITION: MEASURE FOR MEASURE
John D. Barrow reviews Beyond Measure: Conversations Across Art and
Science
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt3X0E4

------------------------------
News and views
------------------------------

OPTICS: LIGHT REINED IN
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtMQ0EO

ELECTRONICS: THE FOURTH ELEMENT
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt3e0EI

-------------------------------
Letters
-------------------------------

A TOPOLOGICAL DIRAC INSULATOR IN A QUANTUM SPIN HALL PHASE
D. Hsieh, D. Qian, L. Wray, Y. Xia, Y. S. Hor, R. J. Cava & M. Z.
Hasan
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtMc0Eg

SMALL PHONON CONTRIBUTION TO THE PHOTOEMISSION KINK IN THE COPPER
OXIDE SUPERCONDUCTORS
Feliciano Giustino, Marvin L. Cohen & Steven G. Louie
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtMd0Eh

THE MISSING MEMRISTOR FOUND
Dmitri B. Strukov, Gregory S. Snider, Duncan R. Stewart & R. Stanley
Williams
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt3v0EZ

HIGH-FREQUENCY MICROMECHANICAL RESONATORS FROM ALUMINIUM–CARBON
NANOTUBE NANOLAMINATES
Jung Hoon Bak et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8i0ER

PROBING THE STRUCTURE OF HETEROGENEOUS DILUTED MATERIALS BY
DIFFRACTION TOMOGRAPHY
Pierre Bleuet
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtTP0EU

BULK SUPERCONDUCTIVITY AT 38 K IN A MOLECULAR SYSTEM
Alexey Y. Ganin et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtSi0Es

MASS PRODUCTION AND DYNAMIC IMAGING OF FLUORESCENT NANODIAMONDS
Yi-Ren Chang et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8j0ES

A MOLECULAR STATE OF CORRELATED ELECTRONS IN A QUANTUM DOT
Sokratis Kalliakos et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtTO0ET

A COMBINATORIAL LIBRARY OF LIPID-LIKE MATERIALS FOR DELIVERY OF RNAI
THERAPEUTICS
Akin Akinc et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8k0ET

OMNIDIRECTIONAL ABSORPTION IN NANOSTRUCTURED METAL SURFACES
T. V. Teperik
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtxR0E7

-------------------------------
Articles
-------------------------------

A SENSITIVITY-ENHANCED FIELD-EFFECT CHIRAL SENSOR
Luisa Torsi et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30BtSx0E8

ELECTRIC-FIELD CONTROL OF LOCAL FERROMAGNETISM USING A MAGNETOELECTRIC
MULTIFERROIC
Ying-Hao Chu et al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8n0EW

ELECTRONIC STRUCTURES OF INTERFACIAL STATES FORMED AT POLYMERIC
SEMICONDUCTOR HETEROJUNCTIONS
Ya-shih Huang at al.
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8o0EX

LABEL-FREE DETECTION OF DNA HYBRIDIZATION BASED ON HYDRATION-INDUCED
TENSION IN NUCLEIC ACID FILMS
Johann Mertens
http://ealerts.nature.com/cgi-bin24/DM/y/ekc30Xztnp0Hi30Bt8p0EY

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from publications across all scientific disciplines.

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IN THIS ISSUE
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In this Issue
http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt7v0Ev

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COMMENTARIES
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When proton pumps go sour: Urinary acidification and kidney stones
C A Wagner
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt7w0Ew
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt7x0Ex

IgA1 glycosylation in IgA nephropathy: As sweet as it can be
J W Eijgenraam and C van Kooten
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt7y0Ey
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt7z0Ez

The dynamics of kidney donation: Viewpoints from the donor, the recipients, and the transplant team
A Maiorano and F P Schena
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt710Em
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt720En

----------------------
JOURNAL CLUB
----------------------
Journal Club
http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt730Eo

----------------------
BOOK REVIEW
----------------------
Kidney Transplantation, 2nd edition
Z Ebcioglu
http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt740Ep

----------------------
MINI REVIEWS
----------------------
The kallikrein-kinin system in diabetic retinopathy: Lessons for the kidney
J A Phipps and E P Feener
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt750Eq
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt760Er

The zebrafish pronephros: A model to study nephron segmentation
R A Wingert and A J Davidson
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt770Es
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt780Et

----------------------
ORIGINAL ARTICLES
----------------------
B-cell O-galactosyltransferase activity, and expression of O-glycosylation genes in bone marrow in IgA nephropathy
K S Buck, A C Smith, K Molyneux, H El-Barbary, J Feehally and J Barratt
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8A0E4
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8B0E5

Mutational analysis of CDKN1B, a candidate tumor-suppressor gene, in refractory secondary//tertiary hyperparathyroidism
K B Lauter and A Arnold
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8C0E6
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8D0E7

Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia
S Faroqui, M Levi, M Soleimani and H Amlal
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8E0E8
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8F0EA

The vacuolar-ATPase B1 subunit in distal tubular acidosis: novel mutations and mechanisms for dysfunction
D G Fuster, J Zhang, X-S Xie and O W Moe
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8G0EB
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8H0EC

Differences in tolerance for health risk to the living donor among potential donors, recipients, and transplant professionals
A Young, M Karpinski, D Treleaven, A Waterman, C R Parikh, H Thiessen-Philbrook, R C Yang and A X Garg
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8I0ED
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8J0EE

Effective and safe treatment with cyclosporine in nephrotic children: A prospective, randomized multicenter trial
K Ishikura, M Ikeda, S Hattori, N Yoshikawa, S Sasaki, K Iijima, K Nakanishi, N Yata and M Honda
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8K0EF
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8L0EG

Free p-cresol is associated with cardiovascular disease in hemodialysis patients
B K I Meijers, B Bammens, B De Moor, K Verbeke, Y Vanrenterghem and P Evenepoel
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8M0EH
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8N0EI

[lsqb]13C2[rsqb]oxalate absorption in children with idiopathic calcium oxalate urolithiasis or primary hyperoxaluria
P Sikora, G E von Unruh, B Beck, M Feldkotter, M Zajaczkowska, A Hesse and B Hoppe
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8O0EJ
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8P0EK

----------------------
TECHNICAL NOTES
----------------------
Controlled formation of biological tubule systems in extracellular matrix gels in vitro
K M Schumacher, S C Phua, A Schumacher and J Y Ying
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8Q0EL
Article: http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8R0EM

----------------------
THE RENAL CONSULT
----------------------
Fabry disease: An underrecognized cause of proteinuria
F C Fervenza, R Torra and D J Lager
http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8S0EN

----------------------
MAKE YOUR DIAGNOSIS
----------------------
The Case [mid] An unknown toxin
Y M K Farag, G P Bayliss and A K Singh
http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8T0EO

----------------------
NEPHROLOGY IMAGE
----------------------
Reversible advanced ischemic hand atrophy due to arteriovenous fistula steal
R Baer, S McDonald, R Wu and M Mantha
http://ealerts.nature.com/cgi-bin24/DM/y/ekcw0Xztnp0Hiy0Bt8U0EP

----------------------

Articles for Kidney International are published online ahead of print through Advance Online Publication (AOP), meaning that the latest research reaches you in the timeliest way possible. Check the AOP webpage each week at www.nature.com/ki/journal/vaop/ncurrent to make sure that you are not left behind.

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[StemCells] Regrow Finger - 4 wks

Video: http://youtube.com/watch?v=pGU5QE_sz8U

The amazing 'pixie dust' made from pigs bladder that regrew a severed
finger in FOUR weeks
By FIONA MACRAE

Scientists are claiming an amazing breakthrough - regrowing a man's
severed finger with the aid of an experimental powder.

Four weeks after Lee Spievack sliced almost half an inch off the top
of one of his fingers, he said it had grown back to its original
length.

Four months later it looked like any other finger, complete
with "great feeling", a fingernail and fingerprint.

The secret to the astonishing regrowth is said to be the powder
described by Mr Spievack, a Cincinnati model shop salesman, as "pixie
dust".

More properly known as extra-cellular matrix, it is bursting with
collagen, the protein that gives skin its strength and elasticity,
and is made from dried pig's bladder.

It was developed to regenerate damaged ligaments in horses. "The
second time I put it on I could already see growth," said Mr
Spievack, 69.

"Each day it was up further. Finally it closed up and was a finger.
It took about four weeks before it was sealed."

Mr Spievack damaged his finger in the propeller of a model plane
three years ago. He turned down a skin graft in favour of the "pixie
dust" recommended by his brother, a former surgeon and the founder of
the firm that makes the powder.

While it is not entirely clear how the powder works, its developers
believe it kick-starts the body's natural healing process by sending
out signals that mobilise the body's own cells into repairing the
damaged tissue.

Dr Stephen Badylak, of the McGowan Institute for Regenerative
Medicine at the University of Pittsburgh, told the BBC: "There are
all sorts of signals in the body.

"We have got signals that are good for forming scar tissue and others
that are good for regenerating tissues.

"One way to think about these matrices is that we've taken out many
of the stimuli for scar tissue formation and left those signals which
were always there for constructive remodelling."

In other words, the powder directs tissues to grow afresh rather than
form scars.

"We're not smart enough to figure out how to regrow a finger," said
Dr Badylak.

"Maybe what we can do is bring all of the pieces of the puzzle to the
right place and then let Mother Nature take its course. There's a lot
more that we don't know than we do know."

But Professor Stephen Kaye, a consultant plastic and hand surgeon at
Leeds University, poured cold water on Dr Badylak's claims.

Asked if he was surprised that Mr Spievack's finger "grew back" he
said: "Not in the slightest."

Prof Kaye added: "The pictures I've seen on the web show a wound I
would have expected to heal and regenerate in any case.

"The end of the finger is extremely good at regeneration. The
pictures we've seen on the web show no evidence of loss of bone,
nerve or tendon material, but regeneration and repair of skin - which
is exactly what the fingertip does."

He added that the photographs appeared to portray a "very commonplace
transverse amputation of the very end of the fingertip" and not
someone who had lost the last phalanx of his finger, as Dr Badylak
claimed.

Prof Kaye said extra-cellular matrix was an acknowldged way of
promoting wound healing, but pointed out that there was a "big
difference" between healing and regeneration.

"I don't want people to have false hopes," he told the Radio 4's The
World Tonight news programme.
http://www.dailymail.co.uk/pages/live/articles/technology/technology.h
tml?in_article_id=563099&in_page_id=1965&ct=5

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StemCells subscribers may also be interested in these sites:

Children's Neurobiological Solutions
http://www.CNSfoundation.org/

Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123

The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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