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World Stem Cell Summit 2010
Wednesday, October 31, 2007
Keyword News: [stem cell]
Mol. Biol. Cell MBC In Press for 31 Oct 2007
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- New Molecular Biology of the Cell MBC In Press articles have been made available
(for the period 24 Oct 2007 to 31 Oct 2007): -
-
Articles
- Regulation of Rtt107 Recruitment to Stalled DNA Replication Forks by the Cullin Rtt101 and the Rtt109 Acetyltransferase
- Tania M. Roberts, Iram Waris Zaidi, Jessica A. Vaisica, Matthias Peter, and Grant W. Brown
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-09-0961
http://www.molbiolcell.org/cgi/content/abstract/E07-09-0961v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-09-0961
- The Structure of the
-Tubulin Small Complex: Implications of Its Architecture and Flexibility for Microtubule Nucleation - Justin M. Kollman, Alex Zelter, Eric G.D. Muller, Bethany Fox, Luke M. Rice, Trisha N. Davis, and David A. Agard
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-09-0879
http://www.molbiolcell.org/cgi/content/abstract/E07-09-0879v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-09-0879
- A Motif in the Clathrin Heavy Chain Required for the Hsc70/Auxilin Uncoating Reaction
- Iris Rapoport, Werner Boll, Anan Yu, Till Böcking, and Tom Kirchhausen
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-09-0870
http://www.molbiolcell.org/cgi/content/abstract/E07-09-0870v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-09-0870
- Precursor Oxidation by Mia40 and Erv1 Promotes Vectorial Transport of Proteins into the Mitochondrial Intermembrane Space
- Judith M.M. Müller, Dusanka Milenkovic, Bernard Guiard, Nikolaus Pfanner, and Agnieszka Chacinska
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-08-0814
http://www.molbiolcell.org/cgi/content/abstract/E07-08-0814v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-08-0814
- The Peripheral Membrane Subunits of the SAM Complex Function Co-dependently in Mitochondrial Outer Membrane Biogenesis
- Nickie C. Chan and Trevor Lithgow
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-08-0796
http://www.molbiolcell.org/cgi/content/abstract/E07-08-0796v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-08-0796
- S100A11, an Dual Mediator for Growth Regulation of Human Keratinocytes
- Masakiyo Sakaguchi, Hiroyuki Sonegawa, Hitoshi Murata, Midori Kitazoe, Jun-ichiro Futami, Ken Kataoka, Hidenori Yamada, and Nam-ho Huh
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-07-0682
http://www.molbiolcell.org/cgi/content/abstract/E07-07-0682v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-07-0682
- Dynamic Association of the Fragile X Mental Retardation Protein as an mRNP between Microtubules and Polyribosomes
- Houping Wang, Jason Dictenberg, Li Ku, Wen Li, Gary J. Bassell, and Yue Feng
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-06-0583
http://www.molbiolcell.org/cgi/content/abstract/E07-06-0583v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-06-0583
- A Novel Function of Arp2p in Mediating Prk1p-specific Regulation of Actin and Endocytosis in Yeast
- Mingji Jin and Mingjie Cai
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-06-0530
http://www.molbiolcell.org/cgi/content/abstract/E07-06-0530v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-06-0530
- Cholecystokinin (CCK) Activates Pancreatic Calcineurin-NFAT Signaling In Vitro and In Vivo
- Grzegorz T. Gurda, LiLi Guo, Sae-Hong Lee, Jeffery D. Molkentin, and John A. Williams
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-05-0430
http://www.molbiolcell.org/cgi/content/abstract/E07-05-0430v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-05-0430
- Distinct Roles for Two G
-G
Interfaces in Cell Polarity Control by a Yeast Heterotrimeric G Protein - Shelly C. Strickfaden and Peter M. Pryciak
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-04-0385
http://www.molbiolcell.org/cgi/content/abstract/E07-04-0385v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-04-0385
- Formation of a Tap/NXF1 Homotypic Complex Is Mediated Through the Amino-Terminal Domain of Tap and Enhances Interaction with Nucleoporins
- Leah H. Matzat, Stephen Berberoglu, and Lyne Lévesque
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-03-0255
http://www.molbiolcell.org/cgi/content/abstract/E07-03-0255v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-03-0255
- The Tyrosine Kinase Activity of c-Src Regulates Actin Dynamics and Organization of Podosomes in Osteoclasts
- Olivier Destaing, Archana Sanjay, Cecile Itzstein, William C. Horne, Derek Toomre, Pietro De Camilli, and Roland Baron
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-03-0227
http://www.molbiolcell.org/cgi/content/abstract/E07-03-0227v1 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-03-0227
- Expansion of the Nucleoplasmic Reticulum Requires the Coordinated Activity of Lamins and CTP:Phosphocholine Cytidylyltransferase (CCT)
- Karsten Gehrig, Rosemary B. Cornell, and Neale D. Ridgway
- Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-02-0179
http://www.molbiolcell.org/cgi/content/abstract/E07-02-0179v2 - Mol. Biol. Cell published 31 October 2007, 10.1091/mbc.E07-02-0179
Mol. Biol. Cell Online MBC In Press Alert
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Tuesday, October 30, 2007
Keyword News: [stem cell]
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[StemCellInformation] The Stem Cell Action Network endorses NJ Stem Cell Research Referendum
The Stem Cell Action Network endorses NJ Stem Cell Research Referendum
The Stem Cell Action Network endorses New Jersey's Stem Cell Research Referendum, which will be on the state ballot in November 2007. This measure, like measures supporting the research in other states, offers hope for effective therapies to millions of Americans suffering from severe illnesses.
The research funded by this measure will include embryonic stem cell research, the most promising basis for developing new remedies and cures. Because the current federal administration bans federal funding for this kind of research, it is all the more important that states provide resources to fill the vacuum. As Faye Armitage points out: "the general consensus among researchers is that embryonic stem cells ... hold the greatest promise to derive treatments that can alleviate the suffering from spinal cord injury and a host of other debilitating and deadly medical conditions."
We are aware that stem cell research funding in New Jersey has, in the past, gone largely to adult stem cell research, and we are concerned that human embryonic stem cell research may in the future be underfunded by the referendum currently under consideration. It's important that that not happen. NJ Senator Ellen Karcher has pointed out in a letter to the state's governor that "If New Jersey wants to become a leader in stem cell research, it must also be a leader in promoting embryonic stem cell research." We in SCAN agree with that sentiment.
Funding agencies can only subsidize, of course, those research proposals that are submitted to them, and among these there may be relatively few that propose to use embryonic stem cells. However, funders can and should actively encourage the submission of research projects that work with human embryonic stem cells, thereby widening the range of projects that might qualify for support.
Nothing said above, however, diminishes our support for the New Jersey referendum. We patient advocates deeply respect and appreciate this effort to make New Jersey a leader in the search for stem cell treatments that will alleviate so much suffering and save so many lives.
SCAN is a nationwide organization. We ask that all of our members and friends across the country do whatever they can to help pass the NJ measure. To begin with, please telephone everyone you know in New Jersey and ask them to vote in favor!
Thank you,
Raymond Barglow, Board of Directors, SCAN
Steve Meyer, Board of Directors, SCAN
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Monday, October 29, 2007
Keyword News: [stem cell]
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| Monday, October 29, 2007 11:31 PM PDT |
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[StemCellInformation] WOMEN OF NEW JERSEY: TIME TO FIGHT!
WOMEN OF NEW
On November 6th, women of
What do stem cells have to do with women's freedom?
You already know. Just ask yourself one question: in a typical family, if someone is injured or becomes ill, on whom does the extra work fall?
All too often—most of the time!-- it is the woman who gets stuck with the chores of caregiving.
It is not right.
But it is reality.
Now, if the illness is a temporary one, like a common cold or the flu, the unfairness is temporary too. Everybody is a little extra careful around Mom, short-tempered because she is working like two people, but in a few days everything gets back to normal.
But what if the sickness or injury is chronic: an incurable condition?
Two people's lives are crippled: the sufferer, and the caregiver.
Slavery is not too strong a word for what the permanent caregiver endures. To have no life of your own, to become the limbs and body of the one you love, to endure agonies of exhaustion, when the back burns with the constant bending and lifting; when the mind goes half-crazy from interrupted sleep, the endless getting up in the night to turn a loved one over in the bed because they are paralyzed and cannot do it; the anguish of having to give pain to a loved one because a catheter has to be inserted, or a gloved hand must reach up into the intestinal tract, and it hurts them—and also there is the secret shame and guilt of resenting him or her… and sometimes in our darkest hours, we may even finding ourselves half-wishing he or she-- or we ourselves-- would die, so the suffering could just stop.
But then the morning comes, and the caregiver gets up somehow, and goes on, dragging herself from chore to chore for endless years, even as her own health breaks down.
It is not enough to say, oh, well, she married him, she took the marriage vows.
And it is never right to say, this is a woman's lot, this is what a woman is expected to do!
Especially not when we may have it in our power to end their suffering.
www.njforcure.
The state of New Jersey has long been inspired by the courage of the Riccio family, how every morning Patricia Riccio tells her paralyzed son Carl—"today I am going to go out and find you a cure", and every day she works to make that promise real.
What if we could make it possible for Ms. Riccio to go home, and say to her son:
"Today is the day; today I found it."
And there is another
Her name is Kavitha Balakrishna and she was—is—a fully accredited medical doctor,
Kavitha went through medical school, fighting for grades as every med student must, enduring the long sleepless nights, and exhaustion—and she prevailed. She won—and she had started her career as a doctor, and was happy in her useful work.
But then her child, a little boy, Pranav, 18 months old, was diagnosed with Spinal Muscle Atrophy (SMA), a vicious disease which slowly saps the strength of the child, taking away their physical abilities, weakening them, until they can no longer breathe.
Kavitha gave up her career as a doctor. Now, she now stays at home to care for her child. When he catches a cold, she sits by his bed all night long, fighting to keep him alive. Pranav is four now, and Kavitha sits there still. If you call her at her house, you will always find her, never more than a few feet from her child's side.
She does this with a full heart, willingly putting her own life on hold -- but nobility does not lessen sacrifice.
So long as her child suffers, so will Kavitha Balakrishna.
Maybe it is time we did something about it.
When November 6th rolls around, the women of
WWW.NJFORHOPE.
To vote YES! on the Stem Cell Research Bond Act is to strike a blow for freedom from the endless prison of incurable illness—not only for our suffering loved ones, but for their caregivers as well—a chance to make somebody free.
Women of
Think it is too late, that cure will not come in time for you? Then think of the girls now growing up, and fight for them. Do you want them to endure what you went through, or maybe what you are going through right now?
First, make sure, you yourself vote: Tuesday, November 6th.
If you need a ride to the voting booths, contact your local Democratic headquarters—
If you can drive, you can do more: give friends and neighbors a ride to the voting booths.
Take your mom. Take your sister. Drag your husband and your Uncle Fred and your Aunt Ethel. Get them to the voting booths.
This will be one of the closest elections in history—because the opponents of the research are using the churches to spread misinformation and flat lies about the research. We don't want to lose half a billion dollars in research funding-- by five or six votes.
You know the truth: stem cell research is good and decent and deserves support.
We must get everybody we can to the polls, November 6th.
And, if you can, chip in a couple bucks, right now. WWW.NJFORHOPE.
Because here is one more great unfairness.
When
Bob Klein took his own money, the profits he had made by working hard for decades—and he gave it to the campaign to pass Proposition 71, California's Stem Cells for Research and Cures Act. He personally donated $3.1 million, and much more. He let the campaign work out of his own offices. He let the campaign take over his life, which meant he lost money because that took him away from his regular job—and he persuaded other champions of charity to contribute.
The result? The campaign had $30 million dollars. There was money for polls and TV ads, money to get the message out, to combat the lies the opposition spread. The truth became known—and
But there are very few people like Bob Klein and Jim and Virginia Stowers, who have both the ability and the willingness to give and give and give.
So brace yourself. How much do you think
One hundred thousand dollars.
That's right. That's all.
What
It isn't fair.
But since when have women ever had it fair?
Maybe it is time to make a change.
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Sunday, October 28, 2007
Keyword News: [stem cell]
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[StemCellInformation] TRY AGAIN----The reporter had it grossly wrong. See below.
The reporter had it grossly wrong. See below.
Your country has achieved notable successes in scientific research
and development. Prominent among these are advances in biotechnology
with the potential to treat and cure illnesses so as to improve the
quality of life in your homeland and abroad. Discoveries in this
field invite man to a deeper awareness of the weighty
responsibilities involved in their application. The use society
hopes to make of biomedical science must constantly be measured
against robust and firm ethical standards (cf. Address to the
Pontifical Academy of Sciences, 6 November 2006). Foremost among
these is the dignity of human life, for under no circumstances may a
human being be manipulated or treated as a mere instrument for
experimentation. The destruction of human embryos, whether to
acquire stem cells or for any other purpose, contradicts the
purported intent of researchers, legislators and public health
officials to promote human welfare. The Church does not hesitate to
approve and encourage somatic stem-cell research—not only because of
the favourable results obtained through these alternative methods,
but more importantly because they harmonize with the aforementioned
intent by respecting the life of the human being at every stage of
his or her existence (cf. Address to the Pontifical Academy for Life
Symposium, 16 September 2006). Mr. Ambassador, I pray that the
inherent moral sensibility of the Korean people, as evidenced by
their rejection of human cloning and related procedures, will help
attune the international community to the deep ethical and social
implications of scientific research and its utilization.
http://tinyurl.
ADDRESS OF HIS HOLINESS BENEDICT XVI
TO H.E. Mr. JI-YOUNG FRANCESCO KIM
AMBASSADOR OF THE REPUBLIC OF KOREA TO THE HOLY SEE
Thursday, 11 October 2007
Your Excellency,
I am pleased to welcome you to the Vatican to accept the Letters of
Credence by which the President of the Republic of Korea has
appointed you Ambassador Extraordinary and Plenipotentiary to the
Holy See. I take this occasion to renew the expression of my respect
and warm affection for the Korean people, and I ask you to convey to
President Roh Moo-hyun and all your fellow citizens my prayerful
good wishes for the peace and prosperity of your nation.
Your Excellency has noted the remarkable growth of the Catholic
Church in your country, due in no small part to the heroic example
of men and women whose faith led them to lay down their lives for
Christ and for their brothers and sisters. Their sacrifice reminds
us that no cost is too great for persevering in fidelity to the
truth. Regrettably, in our contemporary pluralist world some people
question or even deny the importance of truth. Yet objective truth
remains the only sure basis for social cohesion. Truth is not
dependent upon consensus but precedes it and makes it possible,
generating authentic human solidarity. The Church—always mindful of
the truth's power to unite people, and ever attentive to mankind's
irrepressible desire for peaceful coexistence—eagerly strives to
strengthen concord and social harmony both in ecclesial life and
civic life, proclaiming the truth about the human person as known by
natural reason and fully manifested through divine revelation.
Your Excellency, the international community joins with the citizens
of your country in their heightened aspirations for newfound peace
on the Korean peninsula and throughout the region. I take this
opportunity to reiterate the Holy See's support for every initiative
that aims at a sincere and lasting reconciliation, putting an end to
enmity and unresolved grievances. Genuine progress is built on
attitudes of honesty and trust. I commend your country's efforts to
foster fruitful and open dialogue while simultaneously working to
alleviate the pain of those suffering from the wounds of division
and distrust. Indeed, every nation shares in the responsibility of
assuring a more stable and secure world. It is my ardent hope that
the ongoing participation of various countries involved in the
negotiation process will lead to a cessation of programmes designed
to develop and produce weapons with frightening potential for
unspeakable destruction.
Your country has achieved notable successes in scientific research
and development. Prominent among these are advances in biotechnology
with the potential to treat and cure illnesses so as to improve the
quality of life in your homeland and abroad. Discoveries in this
field invite man to a deeper awareness of the weighty
responsibilities involved in their application. The use society
hopes to make of biomedical science must constantly be measured
against robust and firm ethical standards (cf. Address to the
Pontifical Academy of Sciences, 6 November 2006). Foremost among
these is the dignity of human life, for under no circumstances may a
human being be manipulated or treated as a mere instrument for
experimentation. The destruction of human embryos, whether to
acquire stem cells or for any other purpose, contradicts the
purported intent of researchers, legislators and public health
officials to promote human welfare. The Church does not hesitate to
approve and encourage somatic stem-cell research—not only because of
the favourable results obtained through these alternative methods,
but more importantly because they harmonize with the aforementioned
intent by respecting the life of the human being at every stage of
his or her existence (cf. Address to the Pontifical Academy for Life
Symposium, 16 September 2006). Mr. Ambassador, I pray that the
inherent moral sensibility of the Korean people, as evidenced by
their rejection of human cloning and related procedures, will help
attune the international community to the deep ethical and social
implications of scientific research and its utilization.
The promotion of human dignity also summons public authorities to
ensure that young people receive a sound education. Faith-based
schools have much to contribute in this regard. It is incumbent upon
governments to afford parents the opportunity to send their children
to religious schools by facilitating the establishment and financing
of such institutions. Insofar as possible, public subsidies should
free parents from undue financial burdens that attenuate their
ability to choose the most suitable means of educating their
children. Catholic and other religious schools should enjoy the
appropriate latitude of freedom to design and implement curricula
that nurture the life of the spirit without which the life of the
mind is so seriously distorted. I appeal to Church and civic leaders
to move forward in a spirit of cooperation to guarantee a future for
Catholic schooling in your country which will contribute to the
moral and intellectual maturation of the younger generation for the
benefit of all society.
Your Excellency, on this happy occasion as you begin your mission, I
assure you that the Holy See and its various offices will be ever
ready to assist you in carrying out your duties. I invoke divine
blessings upon you, your family and the people of your country, who
hold a special place in my thoughts and prayers at this time.
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[StemCellInformation] The reporter had it grossly wrong. See below.
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