10 July 2008 Volume 454 Number 7201, pp137-252
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----------------------
EDITORIALS
----------------------
The long war against flu p137
That the H5N1 strain of bird flu has not yet caused a pandemic is no
cause for complacency. Preparations for the inevitable must be
redoubled to mitigate the potential devastation.
doi:10.1038/454137a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUl0Eo
An unnecessary battle pp137-138
Neuroscientists and geneticists don't need to be at loggerheads over
the biology of mental disorders.
doi:10.1038/454137b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUm0Ep
A social contract p138
Efforts to inform US military policy with insights from the social
sciences could be a win-win approach.
doi:10.1038/454138a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUn0Eq
----------------------
RESEARCH HIGHLIGHTS
----------------------
Climate science: A watery carbon bank p140
doi:10.1038/454140a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUo0Er
Neuroscience: Rewiring the brain p140
doi:10.1038/454140b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUp0Es
Materials: Colourful clay p140
doi:10.1038/454140c
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUq0Et
Remote sensing: Rainforest shrinkage p140
doi:10.1038/454140d
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUr0Eu
Plant biology: An egg-spedient defence p140
doi:10.1038/454140e
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUs0Ev
Atmospheric chemistry: Forgotten gas pp140-141
doi:10.1038/454140f
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUt0Ew
Ecology: Competing keeps bees busy p141
doi:10.1038/454141a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUu0Ex
Geology: Glacial speeds p141
doi:10.1038/454141b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUv0Ey
Evolution: Photosynthetic ancestors p141
doi:10.1038/454141c
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUw0Ez
Molecular neuroscience: Pores for thought p141
doi:10.1038/454141d
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUx0E1
----------------------
JOURNAL CLUB
----------------------
Journal club p141
Oliver Rando
doi:10.1038/454141e
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUy0E2
----------------------
NEWS
----------------------
Leaders still vague on emissions targets p142
G8 talks fail to advance fight against climate change.
Olive Heffernan
doi:10.1038/454142a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzUz0E3
Researcher battles CNRS reforms p143
Medal winner rallies French scientists.
Declan Butler
doi:10.1038/454143a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU10Ep
Scientists rally to Mexican researchers' plea p143
Dispute threatens to tear physical-sciences institute apart.
Rex Dalton
doi:10.1038/454143b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU20Eq
When there's no room to grow pp144-145
To maintain profits in the face of rising development costs and
slow drug pipelines, big pharmaceutical firms are trying to cut back.
Heidi Ledford examines how GlaxoSmithKline has tried to adapt.
doi:10.1038/454144a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU30Er
A Spanish revival pp147
Spain's Ministry of Science and Innovation was re-established in
April, four years after its dissolution in 2004. Cristina Garmendia,
a former molecular biologist and chief executive of the Genetrix group
of biotech companies, heads the new ministry.
Cristina Jimenez
doi:10.1038/454147a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU40Es
Sidelines p147
Scribbles on the margins of science.
doi:10.1038/454147b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU50Et
Shock tactics point to risk after quake pp148-149
Geologists aim to provide daily hazard maps.
Quirin Schiermeier
doi:10.1038/454148a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU60Eu
Super-sensitive tool key to dark-matter claim pp148-149
Theorists unlock mysteries of experimental results.
Geoff Brumfiel
doi:10.1038/454148b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU70Ev
Boyz 2 pipettemen p149
Lab equipment gets the X factor.
Brendan Maher
doi:10.1038/454149a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzU80Ew
Australian panel lays plans for emissions trading pp150
doi:10.1038/454150a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVA0E7
UK physicists discover full scope of budget cuts p150
doi:10.1038/454150b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVB0E8
India takes pole position to study climate change pp150
doi:10.1038/454150c
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVC0EA
Training for human studies may become mandatory pp150
doi:10.1038/454150d
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVD0EB
Texas educator sues over job loss and creationism pp150
doi:10.1038/454150e
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVE0EC
Iranians face nuclear-study ban in the Netherlands pp150
doi:10.1038/454150f
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVF0ED
NPG Archiving for authors pp150
doi:10.1038/454150g
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVG0EE
----------------------
NEWS FEATURES
----------------------
Archaeology: The lost world pp151-153
Armed with a map depicting a 10,000-year-old landscape submerged
beneath the North Sea and fresh evidence from nearby sites,
archaeologists are realizing that early humans were more territorial
than was previously thought.
Laura Spinney reports.
doi:10.1038/454151a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVH0EF
Psychiatric genetics: The brains of the family pp154-157
Does the difficulty in finding the genes responsible for mental
illness reflect the complexity of the genetics or the poor definitions
of psychiatric disorders?
Alison Abbott reports.
doi:10.1038/454154a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVI0EG
----------------------
CORRESPONDENCE
----------------------
International law should govern release of GM mosquitoes p158
Elena Angulo and Ben Gilna
doi:10.1038/454158a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVJ0EH
Future of open access could be online and peer-reviewed p158
Massimo Sandal
doi:10.1038/454158b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVK0EI
Genetic testing must recognize impact of bad news on recipient pp158-159
Kenneth S. Kosik and Francisco Lopera
doi:10.1038/454158c
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVL0EJ
Action needed to prevent extinctions caused by disease p159
Michael Hoffmann, Clare E. Hawkins and Peter D. Walsh
doi:10.1038/454159a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVM0EK
Cuddly animals don't persuade poor people to back conservation p159
Erik Meijaard and Douglas Sheil
doi:10.1038/454159b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVN0EL
Correction p159
doi:10.1038/454159c
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVO0EM
----------------------
COMMENTARIES
----------------------
The contents of the syringe pp160-161
The influenza vaccine failed this winter. Steven Salzberg suggests
that future success relies on sharing data more widely and making the
virus strain selection process more transparent.
doi:10.1038/454160a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVP0EN
Ready for avian flu? p162
Committing to a vaccine stockpile is just the beginning. Tadataka
Yamada, Alice Dautry and Mark Walport offer a roadmap for heading off
a global avian influenza catastrophe.
doi:10.1038/454162a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVQ0EO
----------------------
BOOKS AND ARTS
----------------------
Testing times for genomics pp163-164
In a bid to popularize the science and ethics of human genetics, two
new books fail to address developments in gene testing since
completion of the Human Genome Project, says Kathy Hudson.
Kathy Hudson reviews Just Genes: The Ethics of Genetic Technologies
by Carol Isaacson BarashDNA: Promise and Peril by Linda L. McCabe
and Edward R.B. McCabe
doi:10.1038/454163a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVR0EP
The cost of vague patents pp164-165
Michael Gollin reviews Patent Failure: How Judges, Bureaucrats, and
Lawyers Put Innovators at Risk by James Bessen and Michael J. Meurer
doi:10.1038/454164a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVS0EQ
A new window on the Victorians pp165-166
Gowan Dawson reviews Victorian Glassworlds: Glass Culture and the
Imagination 1830-1880 by Isobel Armstrong
doi:10.1038/454165a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVT0ER
Culture dish p166
doi:10.1038/454166a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVU0ES
The leaning tower of Perth p166
Keith Hall reviews The Cosmology Gallery
doi:10.1038/454166b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVV0ET
----------------------
ESSAY
----------------------
Behind the looking-glass pp167-168
To understand how mirror neurons help to interpret actions, we must
delve into the networks in which these cells sit,
say Antonio Damasio and Kaspar Meyer.
doi:10.1038/454167a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVW0EU
----------------------
NEWS AND VIEWS
----------------------
Palaeontology: Squint of the fossil flatfish pp169-170
Evolutionary biologists have floundered when trying to explain how the
asymmetrical head of flatfishes came about. 'Gradually' is the answer
arising from exquisite studies of 45-million-year-old fossil specimens.
Philippe Janvier
doi:10.1038/454169a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVX0EV
Planetary science: The early Moon was rich in water pp170-172
Analyses of lunar volcanic glasses show that they are rich in volatile
elements and water. If parts of the lunar mantle contain as much water
as Earth's, does this imply that the water has a common origin?
Marc Chaussidon
doi:10.1038/454170a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVY0EW
50 & 100 Years Ago p171
doi:10.1038/454171a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVZ0EX
Cancer: An unexpected addiction pp172-173
Both oncogenes and normal genes can mediate the development and
progress of cancer. What used to separate their effects was cancer's
dependence on, or 'addiction' to, oncogenes but not normal genes.
Not any more.
John D. Shaughnessy
doi:10.1038/454172a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVa0Ee
Asteroids: How to make a flying saucer pp173-174
Wherever we look in the Solar System, small bodies often seem to come
in twos. Simulations show how asteroids spun in the Sun can produce
such pairings -- one of whose members acquires a strangely familiar
shape.
William F. Bottke
doi:10.1038/454173a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVb0Ef
Solid-state chemistry: New order for lithium bromide pp174-175
It's all very well predicting which forms of crystal an inorganic
solid can adopt, but how can proof be obtained if these structures
aren't thermodynamically stable? The answer is to build them up atom
by atom.
David C. Johnson
doi:10.1038/454174a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVc0Eg
----------------------
BRIEF COMMUNICATIONS ARISING
----------------------
Do female hyaenas choose mates based on tenure? pE1
Russell C. Van Horn, Heather E. Watts and Kay E. Holekamp
doi:10.1038/nature07122
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVd0Eh
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVe0Ei
Honer et al. reply pE2
Oliver P. Honer et al.
doi:10.1038/nature07123
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVf0Ej
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVg0Ek
----------------------
ARTICLE
----------------------
Structure of the Ebola virus glycoprotein bound to an antibody from a
human survivor pp177-182
The crystal structure of Ebola virus glycoprotein is shown in complex
with a neutralizing antibody. The structure suggests that the antibody
prevents infection by preventing conformational changes of GP2
required for fusion.
Jeffrey E. Lee et al.
doi:10.1038/nature07082
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVh0El
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVi0Em
Crystal structure of the ligand-free G-protein-coupled receptor opsin p183
The crystal structure of a ligand free opsin at 2.9 Å resolution is
reported; the entrance pathway for 11 cis retinal and the exit pathway
for all trans retinal are apparent.
Jung Hee Park, Patrick Scheerer, Klaus Peter Hofmann, Hui-Woog Choe
& Oliver Peter Ernst
doi:10.1038/nature07063
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVj0En
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVk0Eo
----------------------
LETTERS
----------------------
Rotational breakup as the origin of small binary asteroids pp188-191
Binary asteroids are created by the slow spin up of a 'rubble pile'
asteroid via the thermal YORP effect (where radiation from an
irregularly shaped body exerts a net force on the body). The mass shed
from the equator of a critically spinning body accretes into a
satellite if the material is collisionally dissipative.
Kevin J. Walsh, Derek C. Richardson and Patrick Michel
doi:10.1038/nature07078
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVl0Ep
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVm0Eq
Volatile content of lunar volcanic glasses and the presence of water
in the Moon's interior pp192-195
A report providing improved limits on the indigenous volatile contents
of the most primitive basalts in the Moon, the lunar volcanic glasses.
The best estimate of the pre eruptive water content of the lunar
volcanic glasses is 745 p.p.m. water, with a minimum of 260 p.p.m.,
indicating that the bulk Moon might not be entirely depleted in highly
volatile elements, including water.
Alberto E. Saal et al.
doi:10.1038/nature07047
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVn0Er
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVo0Es
Quadrupole transitions revealed by Borrmann spectroscopy pp196-199
While electric dipole transitions at the atoms are reduced in the
Borrmann effect, the more exotic electric quadrupole transitions
become stronger. Analysis of the X ray absorption spectra from a
material called gadolinium gallium garnet shows that clear quadrupole
features associate with absorption events, some previously unknown,
in gadolinium.
Robert F. Pettifer, Stephen P. Collins and David Laundy
doi:10.1038/nature07099
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVp0Et
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVq0Eu
A multi-component Fermi surface in the vortex state of an underdoped
high-Tc superconductor pp200-203
Experiments on YBa2Cu3O6.51 reveal more than one carrier pocket, and
evidence is found for the existence of a much larger pocket of heavier
mass carriers having a thermodynamically dominant role in this hole
doped superconductor.
Suchitra E. Sebastian et al.
doi:10.1038/nature07095
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVr0Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVs0Ew
Preseismic velocity changes observed from active source monitoring at
the Parkfield SAFOD drill site pp204-208
Stress changes within seismically active fault zones are shown to be
measurable by exploiting the stress dependence of seismic wave speed
from an active source experiment conducted at the San Andreas Fault
Observatory at Depth drill site, in Parkfield, California.
Fenglin Niu et al.
doi:10.1038/nature07111
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVt0Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVu0Ey
The evolutionary origin of flatfish asymmetry pp209-212
A re-examination of the Eocene fish Amphistium and a description of a
new genus prove that they are the most primitive members of the
flatfish family. In these fish, the migrating eye never gets farther
than the dorsal midline, even in fully adult fishes, providing perhaps
the most graphic and dramatic examples known of a transitional form
spotted in the fossil record.
Matt Friedman
doi:10.1038/nature07108
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVv0Ez
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVw0E1
Social diversity promotes the emergence of cooperation in public goods
games pp213-216
Humans often cooperate with each other, but the temptation to forgo
the public good mostly wins over collective cooperative action. Many
existing models treat individuals as equivalent, ignoring diversity
and population structure; however, here it's shown theoretically that
social diversity, introduced via heterogeneous graphs, promotes the
emergence of cooperation in public goods games.
Francisco C. Santos, Marta D. Santos and Jorge M. Pacheco
doi:10.1038/nature06940
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVx0E2
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVy0E3
An internal thermal sensor controlling temperature preference in
Drosophila p217
It is shown here that flies sense ambient warmth not via their
antennae, but rather by a small set of neurons in the brain. These
'AC' neurons in Drosophila are sensitive to warmth due to the
expression of the warmth activated ion channel dTrpA1.
Fumika N. Hamada et al.
doi:10.1038/nature07001
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzVz0E4
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV10Eq
Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor
signalling and hypoxia p221
This paper shows that Fra 2 controls osteoclast survival and size in
newborn mice, in a process involving a novel biochemical pathway that
includes the protein LIF as well as hypoxia.
Aline Bozec et al.
doi:10.1038/nature07019
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV20Er
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV30Es
IRF4 addiction in multiple myeloma p226
The transcription factor IRF4, required for lymphocyte activation and
plasma cell differentiation, is shown here to be a master regulator of
multiple myeloma. It controls a different network of genes in the
cancer than it does in normal plasma cells or activated B cells.
Arthur L. Shaffer et al.
doi:10.1038/nature07064
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV40Et
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV50Eu
Essential role for Nix in autophagic maturation of erythroid cells p232
This paper shows that a member of the Bcl 2 family, Nix, helps
eliminate organelles by autophagy of the mitochondria. Erythrocytes in
the peripheral blood of Nix-/- mice exhibited mitochondrial retention
and reduced lifespan in vivo.
Hector Sandoval et al.
doi:10.1038/nature07006
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV60Ev
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV70Ew
Imaging the biogenesis of individual HIV-1 virions in live cells p236
This study uses several techniques based on total internal reflection
fluorescence microscopy and live cells expressing fluorescent-protein
tagged derivatives of Gag, the major structural component of HIV 1,
to observe and quantitatively describe the assembly of individual
virus particles in real time.
Nolwenn Jouvenet, Paul D. Bieniasz & Sanford M. Simon
doi:10.1038/nature06998
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzV80Ex
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWA0E8
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian
stem cell lineage p241
This paper shows that the Trim NHL protein Mei P26 restricts growth
and proliferation in the ovarian stem cell lineage. In mei P26
mutants, transit-amplifying cells are larger and proliferate
indefinitely, leading to the formation of an ovarian tumour.
Ralph A. Neumüller et al.
doi:10.1038/nature07014
Abstract: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWB0EA
Article: http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWC0EB
----------------------
CORRIGENDA
----------------------
Neurophysiology: Sensing temperature without ion channels p246
Brandon R. Brown
doi:10.1038/nature07133
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWD0EC
An extremely luminous X-ray outburst at the birth of a supernova p246
A. M. Soderberg et al.
doi:10.1038/nature07134
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWE0ED
----------------------
NATUREJOBS
----------------------
Prospect
Prospects p247
Naturejobs' 'Source Event' activities aim to provide sage careers
advice online and in person.
Gene Russo
doi:10.1038/nj7201-247a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWF0EE
Region
Catalonian powerhouse p248
Spain is revitalizing its science base, with Barcelona surging ahead
as a Mediterranean science hub, reports Quirin Schiermeier.
doi:10.1038/nj7201-248a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWG0EF
Career View
James Ryan, founding dean, Joint School of Nanoscience and
Nanoengineering, North Carolina A&T State University and the
University of North Carolina at Greensboro p250
Nanoscientist aims to set up a major nanotechnology centre.
Virginia Gewin
doi:10.1038/nj7201-250a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWH0EG
Top states vie to fund more science p250
Major life-science initiatives in Massachusetts and Maryland should
mean thousands of science-related jobs.
Paul Smaglik
doi:10.1038/nj7201-250b
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWI0EH
I'll take one 'eureka' please p250
Looking for that eureka moment.
Zachary Lippman
doi:10.1038/nj7201-250c
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWJ0EI
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FUTURES
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Misprint p252
Buyer beware.
Vonda N. McIntyre
doi:10.1038/454252a
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWK0EJ
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ADVANCE ONLINE PUBLICATION
----------------------
09 July 2008
Articles
Switching on and off fear by distinct neuronal circuits
Cyril Herry, Stephane Ciocchi, Verena Senn, Lynda Demmou,
Christian Müller & Andreas Lüthi
doi:10.1038/nature07166
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWL0EK
High-resolution mapping of meiotic crossovers and non-crossovers in
yeast
Eugenio Mancera, Richard Bourgon, Alessandro Brozzi, Wolfgang Huber
& Lars M. Steinmetz
doi:10.1038/nature07135
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWM0EL
Letters
Drosophila RNAi screen identifies host genes important for influenza
virus replication
Linhui Hao et al.
doi:10.1038/nature07151
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWN0EM
Crystal structure of the polymerase PAC–PB1N complex from an avian
influenza H5N1 virus
Xiaojing He et al.
doi:10.1038/nature07120
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWO0EN
Amygdala intercalated neurons are required for expression of fear
extinction
Ekaterina Likhtik, Daniela Popa, John Apergis-Schoute,
George A. Fidacaro & Denis Paré
doi:10.1038/nature07167
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWP0EO
Polo-like kinase-1 is activated by aurora A to promote checkpoint
recovery
Libor Macuarek et al.
doi:10.1038/nature07185
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWQ0EP
A discontinuous hammerhead ribozyme embedded in a mammalian messenger
RNA
Monika Martick, Lucas H. Horan, Harry F. Noller & William G. Scott
doi:10.1038/nature07117
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWR0EQ
06 July 2008
Letters
Minimally invasive high-speed imaging of sarcomere contractile
dynamics in mice and humans
Michael E. Llewellyn, Robert P. J. Barretto, Scott L. Delp
& Mark J. Schnitzer
doi:10.1038/nature07104
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWS0ER
Genome-scale DNA methylation maps of pluripotent and differentiated
cells
Alexander Meissner et al.
doi:10.1038/nature07107
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWT0ES
Stress changes from the 2008 Wenchuan earthquake and increased hazard
in the Sichuan basin
Tom Parsons, Chen Ji & Eric Kirby
doi:10.1038/nature07177
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BzWU0ET
=====================================================================
Laboratory Investigation presents:
'Understanding the development of human bladder cancer by using a
whole-organ genomic mapping strategy'
Can this disease be detected earlier? Genome-wide mapping of human
bladder cancer has identified key genetic risk areas for cancer
development and provides new insight into early genetic origins of cancer.
View the complete article online
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0BvKH0Ey
Laboratory Investigation
http://ealerts.nature.com/cgi-bin24/DM/y/emD10Xztnp0HjB0Fnv0ER
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