Stem cells replace damaged mouse tissue
by MT Bureau - June 18, 2008 - 0 comments
Berkeley, Calif. -- U.S. scientists say they have successfully used
stem cells to repair and replace damaged tissue in mice.
The University of California-Berkeley bioengineers say their
achievement sets the path for research on new treatments for age-
related degenerative conditions such as muscle atrophy or Alzheimer's
and Parkinson's diseases.
The scientists identified two key regulatory pathways that control
how well adult stem cells repair and replace damaged tissue. They
then tweaked how those stem cells reacted to biochemical signals to
revive the ability of muscle tissue in old mice to repair itself
nearly as well as the muscle in much younger mice.
Assistant Professor Irina Conboy who led the research said because
the findings relate to adult stem cells that reside in existing
tissue, the approach to rejuvenating degenerating muscle eliminates
the ethical and medical complications associated with transplanting
tissues grown from embryonic stem cells.
"We are one step closer to having a point of intervention where we
can rejuvenate the body's own stem cells so we don't have to suffer
from some of the debilitating diseases associated with aging," said
Morgan Carlson, the study's lead author.
The findings are reported in the online edition of the journal Nature.
Copyright 2008 by United Press International.
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StemCells subscribers may also be interested in these sites:
Children's Neurobiological Solutions
http://www.CNSfoundation.org/
Cord Blood Registry
http://www.CordBlood.com/at.cgi?a=150123
The CNS Healing Group
http://groups.yahoo.com/group/CNS_Healing
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