Nature Reviews Neurology - Table of Contents alert Volume 5 Issue 10

NATURE REVIEWS NEUROLOGY

October 2009 Volume 5 Number 10

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Nature Reviews Neuroscience
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Focus on CNS Evolution
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Charles Darwin's theory of descent with modification by means of natural
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RESEARCH HIGHLIGHTS
----------------------
Spinal cord injury: Plasticity provides an opportunity for rehabilitation
p519 | doi:10.1038/nrneurol.2009.140
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Stroke: Plasma ADMA: a novel biomarker of subclinical brain injury?
p520 | doi:10.1038/nrneurol.2009.143
http://links.ealert.nature.com/ctt?kn=85&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Stroke: Faster clot busting gets good results
p520 | doi:10.1038/nrneurol.2009.146
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Neuro-Oncology: Talampanel enhances survival in glioblastoma
p521 | doi:10.1038/nrneurol.2009.147
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IN BRIEF
Dementia | Pain | Traumatic brain injury | Stroke
p521 | doi:10.1038/nrneurol.2009.149
http://links.ealert.nature.com/ctt?kn=40&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Parkinson disease: Propagation of disease pathology in PD
p522 | doi:10.1038/nrneurol.2009.142
http://links.ealert.nature.com/ctt?kn=73&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Pain: Coral extract could soothe pain
p522 | doi:10.1038/nrneurol.2009.145
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Lifestyle risk factors for MCD
p523 | doi:10.1038/nrneurol.2009.144
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Stroke: Interleukin-17 and brain injury in stroke
p524 | doi:10.1038/nrneurol.2009.148
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IN BRIEF
Neurodegenerative disease | Parkinson disease | Migraine
p524 | doi:10.1038/nrneurol.2009.150
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NEWS AND VIEWS
----------------------
Neurodegenerative disease: Genetic discrimination in Huntington disease
Stefan M. Pulst
p525 | doi:10.1038/nrneurol.2009.153
A survey conducted in Canada examined the prevalence of perceived genetic
discrimination against patients with Huntington disease. The respondents
reported discrimination not only by insurance or mortgage companies,
but also in family and social contexts. Discrimination was more frequently
attributed to family history than to genetic test results.
http://links.ealert.nature.com/ctt?kn=48&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Stroke: 'Spotting' patients at the highest risk of hematoma growth
Kyra Becker and David Tirschwell
p526 | doi:10.1038/nrneurol.2009.152
Clinical trials aimed at preventing hematoma expansion in patients with
intraparenchymal hemorrhage have failed to show benefit from experimental
intervention. Novel methods for identifying those patients at the
highest risk of hemorrhage growth might enable better patient selection
and, hence, increase the chance of demonstrating an improvement in
clinical outcome.
http://links.ealert.nature.com/ctt?kn=52&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Multiple sclerosis: TNFRSF1A, TRAPS and multiple sclerosis
Tania Kumpfel and Reinhard Hohlfeld
p528 | doi:10.1038/nrneurol.2009.154
A genome-wide association study has identified the R92Q variant of the
TNFRSF1A gene as a new susceptibility locus for multiple sclerosis. This
locus is of special interest because the R92Q substitution was previously
detected in a group of multiple sclerosis patients who had additional
symptoms compatible with the autoinflammatory syndrome TRAPS.
http://links.ealert.nature.com/ctt?kn=22&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Migraine: Treating acute migraine in the emergency department
Daniela Grimaldi and Pietro Cortelli
p529 | doi:10.1038/nrneurol.2009.155
The management of acute migraine in the emergency department presents
a therapeutic challenge for physicians, who need to provide adequate
pain relief while minimizing adverse events and relapses. New research
suggests that phenothiazines are effective drug therapies for acute
migraine, highlighting their potential use as first-line treatments for
acute migraine in the hospital setting.
http://links.ealert.nature.com/ctt?kn=17&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Parkinson disease: Nonmotor symptoms in Parkinson disease: the PRIAMO
study
Ronald F. Pfeiffer
p531 | doi:10.1038/nrneurol.2009.156
Nonmotor symptoms are assuming an increasingly important place in the
constellation of clinical traits that characterize Parkinson disease.
A multicenter survey of patients with Parkinson disease highlights the
prevalence of these symptoms. The findings indicate that further research
into the pathophysiology and treatment of nonmotor symptoms is warranted.
http://links.ealert.nature.com/ctt?kn=15&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

----------------------
REVIEWS
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Parkinson disease and comorbid cerebrovascular disease
Wandana Nanhoe-Mahabier, Karlijn F. de Laat, Jasper E. Visser, Jan Zijlmans,
Frank-Erik de Leeuw and Bastiaan R. Bloem
Published online: 01 September 2009
p533 | doi:10.1038/nrneurol.2009.136
The incidence of Parkinson disease (PD) increases with age, so age-related
conditions are expected to feature prominently among the comorbidities
associated with this disease. In this article, Nanhoe-Mahabier et al.
explore a possible link between PD and cerebrovascular disease, discussing
the pathophysiological mechanisms that could underlie such a relationship,
and considering how comorbid cerebrovascular disease might affect the
clinical presentation of PD.
Abstract: http://links.ealert.nature.com/ctt?kn=43&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=14&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Neurological complications of chronic kidney disease
Arun V. Krishnan and Matthew C. Kiernan
Published online: 01 September 2009
p542 | doi:10.1038/nrneurol.2009.138
Chronic kidney disease is a serious global health problem, and almost
all patients with severe forms of the disease develop neurological
complications, which can include cognitive impairment, cerebrovascular
disease and peripheral neuropathies. Krishnan and Kiernan review the
clinical features and pathophysiology of the most common neurological
complications of chronic kidney disease, and highlight the currently
available treatment options.
Abstract: http://links.ealert.nature.com/ctt?kn=63&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=6&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Predicting responders to therapies for multiple sclerosis
Jordi Rio, Manuel Comabella and Xavier Montalban
p553 | doi:10.1038/nrneurol.2009.139
Early detection of a poor treatment response to disease-modifying agents
could be of great benefit to patients with relapsing-remitting multiple
sclerosis. Such individuals could be switched to a potentially more
effective treatment before too much neurological damage has occurred.
In this Review, Rio and colleagues examine the use of clinical measures,
MRI, and pharmacogenomics in assessing and predicting the treatment
response in patients with this condition.
Abstract: http://links.ealert.nature.com/ctt?kn=60&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=38&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

Biological fluid biomarkers in neurodegenerative parkinsonism
Michael Eller and David R. Williams
Published online: 01 September 2009
p561 | doi:10.1038/nrneurol.2009.135
Clinical overlap between the various types of neurodegenerative
parkinsonism, particularly in the early stages of disease, can make
differential diagnosis problematic. Biological fluid biomarker assays
are being explored as adjunctive tests to aid the diagnostic work-up
of patients with neurodegenerative parkinsonism, and in this article
Eller and Williams cast a critical eye over the currently available
cerebrospinal fluid, plasma and urine biomarkers.
Abstract: http://links.ealert.nature.com/ctt?kn=64&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=33&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0

----------------------
CASE STUDY
----------------------
Cortical activity and hand function restoration in a patient after
spinal cord surgery
Thomas Carlstedt, Tomas Hultgren, Torbjorn Nyman and Thomas Hansson
p571 | doi:10.1038/nrneurol.2009.137
Complete brachial plexus injury leads to paralysis and loss of sensation
in the affected arm and hand. Carlstedt et al. present a long-term
follow-up assessment of a 9-year-old boy who underwent spinal cord
surgery after sustaining such an injury in a motorcycle accident. The
patient showed recovery of hand motor function without restoration of
sensation.
Abstract: http://links.ealert.nature.com/ctt?kn=26&m=34090527&r=MTc2NDUyMzIwMwS2&b=2&j=NTg3Mjg5MjUS1&mt=1&rt=0
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-------------------------------
Editorial
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Back on the map
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Iranian ministers in plagiarism row
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-------------------------------
Column
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Party of one: Innovation strategy
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News Features
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Eastern Europe: Scaling the wall
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Eastern Europe: Beyond the bloc
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Opinion
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Science and the Stasi
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Optics: Droplets set light in a spin
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Applied physics: Lasers go nano
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Letters
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Universality of galactic surface densities within one dark halo
scale-length
Gianfranco Gentile et al.
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Plasmon lasers at deep subwavelength scale
Rupert F. Oulton et al.
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Broken-symmetry states and divergent resistance in suspended bilayer
graphene
Benjamin E. Feldman, Jens Martin & Amir Yacoby
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Laser-driven soft-X-ray undulator source
Matthias Fuchs et al.
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Energy gaps and a zero-field quantum Hall effect in graphene by
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F. Guinea, M. I. Katsnelson & A. K. Geim
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Single-shot qubit readout in circuit quantum electrodynamics
Francois Mallet et al.
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Atomic-scale mapping of quantum dots formed by droplet epitaxy
Divine P. Kumah et al.
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Low-divergence single-mode terahertz quantum cascade laser
M. I. Amanti et al.
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Ultrafast waveform compression using a time-domain telescope
Mark A. Foster et al.
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Excitonic switches operating at around 100 K
G. Grosso et al.
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Articles
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Electrically tunable liquid crystal optical microresonators
M. Humar et al.
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BRITISH JOURNAL OF CANCER

Volume 101 Number 7
Published online 29 September 2009 (1033 - 1224)

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----------------------
CLINICAL STUDIES
----------------------
Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial
A Okines, O del Puerto, D Cunningham, I Chau, E Van Cutsem, L Saltz and J Cassidy
Abstract: http://links.ealert.nature.com/ctt?kn=4&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=86&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Capecitabine in combination with irinotecan (XELIRI), administered as a 2-weekly schedule, as first-line chemotherapy for patients with metastatic colorectal cancer: a phase II study of the Spanish GOTI group
P Garcia-Alfonso, A Munoz-Martin, M Mendez-Urena, R Quiben-Pereira, E Gonzalez-Flores and G Perez-Manga
Abstract: http://links.ealert.nature.com/ctt?kn=85&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=84&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker
P N Munster, D Marchion, S Thomas, M Egorin, S Minton, G Springett, J-H Lee, G Simon, A Chiappori, D Sullivan and A Daud
Abstract: http://links.ealert.nature.com/ctt?kn=91&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=90&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Atacicept in relapsed/refractory multiple myeloma or active Waldenstrom's macroglobulinemia: a phase I study
J-F Rossi, J Moreaux, D Hose, G Requirand, M Rose, V Rouille, I Nestorov, G Mordenti, H Goldschmidt, A Ythier and B Klein
Abstract: http://links.ealert.nature.com/ctt?kn=89&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=88&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Evaluation of the paclitaxel-ifosfamide-cisplatin (TIP) combination in relapsed and/or metastatic cervical cancer
C Kosmas, N Mylonakis, G Tsakonas, G Vorgias, N Karvounis, N Tsavaris, T Daladimos, N Kalinoglou, N Malamos, T Akrivos and A Karabelis
Abstract: http://links.ealert.nature.com/ctt?kn=119&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=121&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Role of CT scan-based and clinical evaluation in the preoperative prediction of optimal cytoreduction in advanced ovarian cancer: a prospective trial
G Ferrandina, G Sallustio, A Fagotti, G Vizzielli, A Paglia, E Cucci, A Margariti, L Aquilani, G Garganese and G Scambia
Abstract: http://links.ealert.nature.com/ctt?kn=13&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=15&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

An investigation into the performance of the Adjuvant! Online prognostic programme in early breast cancer for a cohort of patients in the United Kingdom
H E Campbell, M A Taylor, A L Harris and A M Gray
Abstract: http://links.ealert.nature.com/ctt?kn=14&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=17&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Cause-specific mortality in classic Kaposi's sarcoma: a population-based study in Italy (1995-2002)
V Ascoli, G Minelli, M Kanieff, R Crialesi, L Frova and S Conti
Abstract: http://links.ealert.nature.com/ctt?kn=16&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=19&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Bladder cancer in cancer patients: population-based estimates from a large Swedish study
J Lorenzo Bermejo, J Sundquist and K Hemminki
Abstract: http://links.ealert.nature.com/ctt?kn=18&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=22&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

----------------------
TRANSLATIONAL THERAPEUTICS
----------------------
Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model
M Yashiro, O Shinto, K Nakamura, M Tendo, T Matsuoka, T Matsuzaki, R Kaizaki, M Ohira, A Miwa and K Hirakawa
Abstract: http://links.ealert.nature.com/ctt?kn=21&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=93&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma
N M A White, M Mathews, G M Yousef, A Prizada, C Popadiuk and J J E Dore
Abstract: http://links.ealert.nature.com/ctt?kn=106&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=107&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activity
B J Stish, S Oh, H Chen, A Z Dudek, R A Kratzke and D A Vallera
Abstract: http://links.ealert.nature.com/ctt?kn=104&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=105&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

----------------------
MOLECULAR DIAGNOSTICS
----------------------
The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro
D Qualtrough, K Singh, N Banu, C Paraskeva and M Pignatelli
Abstract: http://links.ealert.nature.com/ctt?kn=101&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=103&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Cancer phenotype as the outcome of an evolutionary game between normal and malignant cells
D Dingli, F A C C Chalub, F C Santos, S Van Segbroeck and J M Pacheco
Abstract: http://links.ealert.nature.com/ctt?kn=99&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=100&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Hsp-27 expression at diagnosis predicts poor clinical outcome in prostate cancer independent of ETS-gene rearrangement
C S Foster, A R Dodson, L Ambroisine, G Fisher, H Moller, J Clark, G Attard, J De-Bono, P Scardino, V E Reuter, C S Cooper, D M Berney and J Cuzick on behalf of the Trans-Atlantic Prostate Group
Abstract: http://links.ealert.nature.com/ctt?kn=94&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=96&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility
T Nedjadi, N Kitteringham, F Campbell, R E Jenkins, B K Park, P Navarro, F Ashcroft, A Tepikin, J P Neoptolemos and E Costello
Abstract: http://links.ealert.nature.com/ctt?kn=122&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=123&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin
S Bafna, S Kaur, N Momi and S K Batra
Abstract: http://links.ealert.nature.com/ctt?kn=124&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=115&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

CA 19-9 as a biomarker in advanced pancreatic cancer patients randomised to gemcitabine plus axitinib or gemcitabine alone
H S Wasan, G M Springett, C Chodkiewicz, R Wong, J Maurel, C Barone, B Rosbrook, A D Ricart, S Kim and J-P Spano
Abstract: http://links.ealert.nature.com/ctt?kn=116&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=117&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

BRCA1 tumours correlate with a HIF-1[alpha] phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression
M Yan, M Rayoo, E A Takano, H Thorne and S B Fox
Abstract: http://links.ealert.nature.com/ctt?kn=118&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=110&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma
N S Vasudev, S Sim, D A Cairns, R E Ferguson, R A Craven, A Stanley, J Cartledge, D Thompson, P J Selby and R E Banks
Abstract: http://links.ealert.nature.com/ctt?kn=111&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=114&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

VEGF121b, a new member of the VEGFxxxb family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo
E S Rennel, A H R Varey, A J Churchill, E R Wheatley, L Stewart, S Mather, D O Bates and S J Harper
Abstract: http://links.ealert.nature.com/ctt?kn=64&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=65&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Salivary analysis of oral cancer biomarkers
T Shpitzer, Y Hamzany, G Bahar, R Feinmesser, D Savulescu, I Borovoi, M Gavish and R M Nagler
Abstract: http://links.ealert.nature.com/ctt?kn=61&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=62&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

----------------------
EPIDEMIOLOGY
----------------------
A cohort study of the risk of cancer associated with type 2 diabetes
A A Ogunleye, S A Ogston, A D Morris and J M M Evans
Abstract: http://links.ealert.nature.com/ctt?kn=57&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=58&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Serum triglyceride concentrations and cancer risk in a large cohort study in Austria
H Ulmer, W Borena, K Rapp, J Klenk, A Strasak, G Diem, H Concin and G Nagel VHM & PP Study Group
Abstract: http://links.ealert.nature.com/ctt?kn=55&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=56&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Cannabis, tobacco and domestic fumes intake are associated with nasopharyngeal carcinoma in North Africa
B-J Feng, M Khyatti, W Ben-Ayoub, S Dahmoul, M Ayad, F Maachi, W Bedadra, M Abdoun, S Mesli, H Bakkali, M Jalbout, M Hamdi-Cherif, K Boualga, N Bouaouina, L Chouchane, A Benider, F Ben-Ayed, D E Goldgar and M Corbex
Abstract: http://links.ealert.nature.com/ctt?kn=59&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=60&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Birth intervals and breast cancer risk
A Kauppila, P Kyyronen, M Hinkula and E Pukkala
Abstract: http://links.ealert.nature.com/ctt?kn=76&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=77&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

----------------------
LETTERS TO THE EDITOR
----------------------
Somatic mutations are present in all members of the AKT family in endometrial carcinoma
A Dutt, H B Salvesen, H Greulich, W R Sellers, R Beroukhim and M Meyerson
http://links.ealert.nature.com/ctt?kn=82&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Reply: Somatic mutations are present in all members of the AKT family in endometrial carcinoma
K Shoji, K Oda, S Nakagawa, S Hosokawa, G Nagae, Y Uehara, K Sone, Y Miyamoto, H Hiraike, O Hiraike-Wada, T Nei, K Kawana, H Kuramoto, H Aburatani, T Yano and Y Taketani
http://links.ealert.nature.com/ctt?kn=69&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Predictive factors for severe toxicity of sunitinib in unselected patients with advanced renal cell cancer
H Rezaei Kalantari
http://links.ealert.nature.com/ctt?kn=71&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

Reply: Predictive factors for severe toxicity of sunitinib in unselected patients with advanced renal cell cancer
A A M van der Veldt, E Boven, A J M van den Eertwegh and J B A G Haanen
http://links.ealert.nature.com/ctt?kn=73&m=34090078&r=MTc2MDAwMTgxNgS2&b=2&j=NTg3MjQyMzkS1&mt=1&rt=0

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EMBO Reports - Table of Contents alert Volume 10 Issue 10, pp 1067-1182

EMBO REPORTS TABLE OF CONTENTS

October 2009 Volume 10 Number 10, pp 1067-1182
(c) Copyright 2009 by the European Molecular Biology Organization
Now available at http://links.ealert.nature.com/ctt?kn=17&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

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*********************************************************************

Contents: Volume 10, Number 10 (October 2009)

---------------------
EDITORIAL
---------------------

Pay to cite.
Howy Jacobs
http://links.ealert.nature.com/ctt?kn=43&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

---------------------
SCIENCE AND SOCIETY
---------------------

OPINION

Logophobia.
Massimo Pigliucci
http://links.ealert.nature.com/ctt?kn=88&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

VIEWPOINTS

The role of means and goals in technology acceptance. A differentiated landscape of public perceptions of pharming.
Rafael Pardo, Margret Engelhard, Kristin Hagen, Rikke Bagger Jorgensen, Eckard Rehbinder, Angelika Schnieke, Mariana Szmulewicz & Felix Thiele
http://links.ealert.nature.com/ctt?kn=92&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

Genomics for citizens. Providing the public with more and better knowledge to address the challenges of the twenty-first century.
Jacques Dubochet
http://links.ealert.nature.com/ctt?kn=87&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

ANALYSES

The end of monkey research? New legislation and public pressure could jeopardize research with primates in both Europe and the USA.
Melissa Suran & Howard Wolinsky
http://links.ealert.nature.com/ctt?kn=76&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

The secret garden. The human digestive system is teeming with microbiotic life, but just how important are these interlopers for health and disease?.
Philip Hunter
http://links.ealert.nature.com/ctt?kn=44&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

---------------------
REVIEWS
---------------------

MEETING REPORT

Molecular aspects of male fertility. International Workshop on Molecular Andrology.
Stephen A. Krawetz, Dirk G. De Rooij & Mark P. Hedger
http://links.ealert.nature.com/ctt?kn=41&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

LITERATURE REPORT

Just say NO: nitric oxide regulation of Hsp90.
Bradley T. Scroggins & Len Neckers
http://links.ealert.nature.com/ctt?kn=28&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

CONCEPT

A matter of choice: the establishment of sister chromatid cohesion.
Frank Uhlmann
http://links.ealert.nature.com/ctt?kn=24&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=37&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

REVIEW

Hidden talents of natural killers: NK cells in innate and adaptive immunity.
Megan A. Cooper, Marco Colonna & Wayne M. Yokoyama
http://links.ealert.nature.com/ctt?kn=14&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=15&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

---------------------
SCIENTIFIC REPORTS
---------------------

Intracellular regulation of human ClC-5 by adenine nucleotides.
Giovanni Zifarelli & Michael Pusch
http://links.ealert.nature.com/ctt?kn=18&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=19&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth.
Andrea Burgo, Emmanuel Sotirakis, Marie-Christine Simmler, Agathe Verraes, Christophe Chamot, Jeremy C Simpson, Letizia Lanzetti, Véronique Proux-Gillardeaux & Thierry Galli
http://links.ealert.nature.com/ctt?kn=11&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=9&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription.
Mei Nie, Saima Aijaz, Isabelle V Leefa Chong San, Maria S Balda & Karl Matter
http://links.ealert.nature.com/ctt?kn=83&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=78&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

Regulation of nucleolar signalling to p53 through NEDDylation of L11.
Anders Sundqvist, Geng Liu, Antonis Mirsaliotis & Dimitris P Xirodimas
http://links.ealert.nature.com/ctt?kn=75&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
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The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway.
Haiyun Song, Chloe Spichiger-Haeusermann & Konrad Basler
http://links.ealert.nature.com/ctt?kn=68&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
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Hsp90 is regulated by a switch point in the C-terminal domain.
Marco Retzlaff, Michael Stahl, H Christian Eberl, Stephan Lagleder, Jurgen Beck, Horst Kessler & Johannes Buchner
http://links.ealert.nature.com/ctt?kn=55&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
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Vesicular stomatitis virus inhibits mitotic progression and triggers cell death.
Papia Chakraborty, Joachim Seemann, Ram K Mishra, Jen-Hsuan Wei, Lauren Weil, Daniel R Nussenzveig, Joshua Heiber, Glen N Barber, Mary Dasso & Beatriz M A Fontoura
http://links.ealert.nature.com/ctt?kn=53&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=52&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

Nucleocytoplasmic transport of Alp7/TACC organizes spatiotemporal microtubule formation in fission yeast.
Masamitsu Sato, Naoyuki Okada, Yasutaka Kakui, Masayuki Yamamoto, Minoru Yoshida & Takashi Toda
http://links.ealert.nature.com/ctt?kn=23&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=30&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

ING2 controls the progression of DNA replication forks to maintain genome stability.
Delphine Larrieu, Damien Ythier, Romuald Binet, Christian Brambilla, Elisabeth Brambilla, Sagar Sengupta & Rémy Pedeux
http://links.ealert.nature.com/ctt?kn=32&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
http://links.ealert.nature.com/ctt?kn=36&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0

A role for the CREB co-activator CRTC2 in the hypothalamic mechanisms linking glucose sensing with gene regulation.
Robin G Lerner, Chantal Depatie, Guy A Rutter, Robert A Screaton & Nina Balthasar
http://links.ealert.nature.com/ctt?kn=39&m=34089958&r=MTc2MDI0MTQ4MQS2&b=2&j=NTg3MjI0NzES1&mt=1&rt=0
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---------------------
SCIENCE AND SOCIETY
---------------------

CORRIGENDUM

Homo economicus?.
Andrea Rinaldi
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Kidney International - Table of Contents alert Volume 76 Issue 8

KIDNEY INTERNATIONAL

October 2009 Volume 76 Number 8, pp 805 - 918

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----------------------
IN THIS ISSUE
----------------------
In this Issue
http://links.ealert.nature.com/ctt?kn=64&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
EDITORIAL
----------------------
Race: a call to change nomenclature
Eberhard Ritz and Sarala Naicker
http://links.ealert.nature.com/ctt?kn=76&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
JOURNAL CLUB
----------------------
Journal Club
http://links.ealert.nature.com/ctt?kn=81&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
COMMENTARIES
----------------------
Licorice: a sweet alternative to prevent hyperkalemia in dialysis patients?
Paolo Ferrari
Abstract: http://links.ealert.nature.com/ctt?kn=84&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=67&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Uremic memory: the role of acute kidney injury in long-term outcomes
Ladan Golestaneh, Michal L Melamed and Thomas H Hostetter
Abstract: http://links.ealert.nature.com/ctt?kn=69&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=72&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Sphingosine kinase-1: a potential mediator of renal fibrosis
David A Long and Karen L Price
Abstract: http://links.ealert.nature.com/ctt?kn=14&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=13&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
MINI REVIEWS
----------------------
Hepatitis C virus-induced cryoglobulinemia
Edgar D Charles and Lynn B Dustin
Abstract: http://links.ealert.nature.com/ctt?kn=12&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=10&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Steroid-free maintenance immunosuppression in kidney transplantation: is it time to
consider it as a standard therapy[quest]
Fu L Luan, Diane E Steffick and Akinlolu O Ojo
Abstract: http://links.ealert.nature.com/ctt?kn=9&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=6&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

The biology of preeclampsia
Keizo Kanasaki and Raghu Kalluri
Abstract: http://links.ealert.nature.com/ctt?kn=109&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=106&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
ORIGINAL ARTICLES
----------------------
Induction of heme oxygenase-1 protects against podocyte apoptosis under diabetic conditions
Sang Choel Lee, Seung Hyeok Han, Jin Ji Li, Sun Ha Lee, Dong-Sub Jung, Seung-Jae Kwak,
Seung Hye Kim, Dong Ki Kim, Tae-Hyun Yoo, Jin Hyun Kim, Se-Ho Chang, Dae Suk Han and Shin-Wook Kang
Abstract: http://links.ealert.nature.com/ctt?kn=111&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=110&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral
10 pS chloride channel in the rat thick ascending limb
Rui-Min Gu, Lei Yang, Yunhong Zhang, Lijun Wang, Shumin Kong, Chengbiao Zhang,
Yuanyuan Zhai, Mingxiao Wang, Peng Wu, Liping Liu, Feng Gu, Jiye Zhang and Wen-Hui Wang
Abstract: http://links.ealert.nature.com/ctt?kn=94&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=96&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Transforming growth factor-[beta]2 upregulates sphingosine kinase-1 activity, which in
turn attenuates the fibrotic response to TGF-[beta]2 by impeding CTGF expression
Shuyu Ren, Andrea Babelova, Kristin Moreth, Cuiyan Xin, Wolfgang Eberhardt, Anke Doller,
Hermann Pavenstadt, Liliana Schaefer, Josef Pfeilschifter and Andrea Huwiler
Abstract: http://links.ealert.nature.com/ctt?kn=97&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=98&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Deletion of the Met receptor in the collecting duct decreases renal repair
following ureteral obstruction
Hong Ma, Maryanna Saenko, Anthony Opuko, Akashi Togawa, Keita Soda, Arnaud Marlier,
Gilbert W Moeckel, Lloyd G Cantley and Shuta Ishibe
Abstract: http://links.ealert.nature.com/ctt?kn=101&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=102&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Glycyrrhetinic acid food supplementation lowers serum potassium concentration in chronic
hemodialysis patients
Stefan Farese, Anja Kruse, Andreas Pasch, Bernhard Dick, Brigitte M Frey,
Dominik E Uehlinger and Felix J Frey
Abstract: http://links.ealert.nature.com/ctt?kn=104&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=135&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

A small post-operative rise in serum creatinine predicts acute kidney injury in
children undergoing cardiac surgery
Michael Zappitelli, Pierre-Luc Bernier, Richard S Saczkowski, Christo I Tchervenkov,
Ronald Gottesman, Adrian Dancea, Ayaz Hyder and Omar Alkandari
Abstract: http://links.ealert.nature.com/ctt?kn=133&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=131&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease
Lowell J Lo, Alan S Go, Glenn M Chertow, Charles E McCulloch, Dongjie Fan,
Juan D Ordonez and Chi-yuan Hsu
Abstract: http://links.ealert.nature.com/ctt?kn=120&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=121&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

The impact of transient and persistent acute kidney injury on long-term outcomes
after acute myocardial infarction
Alexander Goldberg, Elena Kogan, Haim Hammerman, Walter Markiewicz and Doron Aronson
Abstract: http://links.ealert.nature.com/ctt?kn=117&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=118&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
THE RENAL CONSULT
----------------------
Human immunodeficiency virus and renal transplantation
Rajani V Dinavahi, Anita Mehrotra, Barbara T Murphy and Shirish Huprikar
Abstract: http://links.ealert.nature.com/ctt?kn=127&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=130&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
LETTERS TO THE EDITOR
----------------------
Pitfalls of technetium-99m-labeled human serum albumin scintigraphy for
protein-losing enteropathy
Yu-Juei Hsu, Shih-Hua Lin, Yuh-Feng Lin, Fu-Chiu Yu and Lamin E S Jaiteh
http://links.ealert.nature.com/ctt?kn=126&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Response to 'Pitfalls of technetium-99m-labeled human serum albumin scintigraphy for
protein-losing enteropathy'
Yi-Chun Chen, Jainn-Shiun Chiu and Yuh-Feng Wang
http://links.ealert.nature.com/ctt?kn=58&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

The utility of multivariate analysis in the study of hepcidin
Joshua J Zaritsky and Brian Y Young
http://links.ealert.nature.com/ctt?kn=52&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Response to 'The utility of multivariate analysis in the study of hepcidin'
Damien R Ashby, Daniel P Gale, Mark Busbridge, Patrick H Maxwell and Peter Choi
http://links.ealert.nature.com/ctt?kn=54&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic
acid production and arterial blood pressure
Cristiano Fava, Martina Montagnana and Olle Melander
http://links.ealert.nature.com/ctt?kn=47&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Response to 'Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic
acid production and arterial blood pressure'
Xiaoliang Liu and Yanyan Zhao
http://links.ealert.nature.com/ctt?kn=49&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

The data on transplantation in Saudi Arabia are complex and require additional
framework for interpretation
Luc Noel
http://links.ealert.nature.com/ctt?kn=88&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Response to 'The data on transplantation in Saudi Arabia are complex and require
additional framework for interpretation'
Lucy D Horvat and Amit X Garg
http://links.ealert.nature.com/ctt?kn=63&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Mineral complexes and vascular calcification
W Charles O'Neill
http://links.ealert.nature.com/ctt?kn=83&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Response to 'Mineral complexes and vascular calcification'
Isao Matsui, Takayuki Hamano, Satoshi Mikami, Yoshitaka Isaka and Hiromi Rakugi
http://links.ealert.nature.com/ctt?kn=77&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Enterovesical fistula and roundworms
Weekitt Kittisupamongkol
http://links.ealert.nature.com/ctt?kn=73&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

Complications impair the usefulness and validity of the rat tail arteriovenous fistula model
John S Beatty, Paul F Wach, William D Paulson, Todd D Merchen, David M Pollock,
Jennifer S Pollock and John J White
http://links.ealert.nature.com/ctt?kn=68&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

First use of nocturnal hemodialysis
Christopher R Blagg
http://links.ealert.nature.com/ctt?kn=25&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

----------------------
NEPHROLOGY IMAGE
----------------------
Endovascular repair of a hemodialysis fistula aneurysm with covered stents
Murty L Mantha, Richard Baer, Georgina S Bailey, Roxanne L Wu and John P Killen
http://links.ealert.nature.com/ctt?kn=33&m=34089946&r=MTc2MzAwNDQzNwS2&b=2&j=NTg3MjIzNjES1&mt=1&rt=0

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Nature Reviews Gastroenterology & Hepatology - Table of Contents alert Volume 6 Issue 10

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY

October 2009 Volume 6 Number 10

Visit Nature Reviews Gastroenterology & Hepatology online to browse
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Now available at
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----------------------
EDITORIAL
----------------------
The wrong end of the scope
Stephen B. Hanauer
p559 | doi:10.1038/nrgastro.2009.164
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----------------------
RESEARCH HIGHLIGHTS
----------------------
IBD: Risk of IBD increases after Salmonella or Campylobacter gastroenteritis
p561 | doi:10.1038/nrgastro.2009.152
http://links.ealert.nature.com/ctt?kn=56&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

Esophagus: Longitudinal esophageal muscle dysfunction reported in
eosinophilic esophagitis
p562 | doi:10.1038/nrgastro.2009.155
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Cancer: Asbestos exposure linked to digestive cancer
p562 | doi:10.1038/nrgastro.2009.156
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Cancer: Diabetes therapies affect pancreatic cancer risk
p563 | doi:10.1038/nrgastro.2009.151
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Chronic hepatitis C progression
p563 | doi:10.1038/nrgastro.2009.153
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Infectious disease: Typhoid vaccine effective
p563 | doi:10.1038/nrgastro.2009.154
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Surgery: Glycemic control after bariatric surgery
p564 | doi:10.1038/nrgastro.2009.157
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Endoscopy: Capsule endoscopy: a new technique for colon cancer screening?
p564 | doi:10.1038/nrgastro.2009.158
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----------------------
NEWS AND VIEWS
----------------------
Hepatitis: Monitoring drug therapy for hepatitis B-a global challenge?
Tin Nguyen and Stephen Locarnini
p565 | doi:10.1038/nrgastro.2009.160
A new study has found undetectable serum levels of HBV DNA at week 24 of
treatment to be the strongest predictor of optimal outcomes for patients
with chronic HBV infection. Although this finding is not surprising, it
has important implications for those patients on antiviral therapy who
do not achieve a favorable response.
http://links.ealert.nature.com/ctt?kn=7&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

Colorectal cancer: What do studies of diet patterns tell us?
Marjorie L. McCullough
p567 | doi:10.1038/nrgastro.2009.159
Among the challenges of studying the contribution of individual dietary
factors to cancer risk is the interwoven nature of diet-dietary factors
are often correlated and eating patterns are complex. A large, prospective
epidemiological study of diet patterns used cluster analyses to
demonstrate the benefit of a fruit and vegetable diet to colorectal
cancer risk.
http://links.ealert.nature.com/ctt?kn=44&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

Colorectal cancer: Management of small polyps detected by CT colonography
Perry J. Pickhardt
p568 | doi:10.1038/nrgastro.2009.161
A recent survey of patients, primary physicians and gastroenterologists
found that an overwhelming majority prefer endoscopic polypectomy for
small polyps detected by screening CT colonography. These hypothetical
results, however, strongly contradict results in actual clinical practice.
http://links.ealert.nature.com/ctt?kn=42&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

Hepatitis C: CIFN for re-treatment of PEG-IFN plus RBV nonresponders?
Christian Trepo and Pierre Pradat
p570 | doi:10.1038/nrgastro.2009.145
The current re-treatment options available to patients with chronic
hepatitis C who fail to respond to treatment with pegylated interferon
plus ribavirin are limited. Findings from a large, multicenter study
suggest that re-treatment with consensus interferon plus ribavirin
should now be considered for compliant, motivated nonresponders.
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Surgery: A midline or transverse abdominal incision?
Henrik Kehlet
p571 | doi:10.1038/nrgastro.2009.150
Whether a midline or transverse incision is used in abdominal surgery
depends mainly on the disease, anatomy and potential effects on wound
healing, pain and postoperative complications. Decisions can, however,
be based on a surgeon's experience and preference, as the procedures'
respective benefits remain to be clearly delineated.
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----------------------
REVIEWS
----------------------
The clinical use of HVPG measurements in chronic liver disease
Jaime Bosch, Juan G. Abraldes, Annalisa Berzigotti and Juan Carlos
Garcia-Pagan
Published online: 01 September 2009
p573 | doi:10.1038/nrgastro.2009.149
Hepatic venous pressure gradient (HVPG) is the most useful parameter
for the assessment of patients with cirrhosis. HVPG provides diagnostic
and prognostic information in several clinical scenarios: treatment of
portal hypertension, surgery for hepatocellular carcinoma, treatment
of HCV-related or HBV-related cirrhosis, and outcome of recurrent HCV
infection after liver transplantation.
Abstract: http://links.ealert.nature.com/ctt?kn=45&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=71&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

Pathophysiology, diagnosis and management of postoperative dumping
syndrome
Jan Tack, Joris Arts, Philip Caenepeel, Dominiek De Wulf and Raf Bisschops
Published online: 01 September 2009
p583 | doi:10.1038/nrgastro.2009.148
The signs and symptoms of dumping syndrome, a well-established complication
of gastric and esophageal surgery, result from rapid gastric emptying
and the delivery of large particles of poorly digested food to the small
bowel. These symptoms, which can be classed as early or late, their
pathophysiological basis, and the treatment options available to patients
with dumping syndrome are outlined in this article.
Abstract: http://links.ealert.nature.com/ctt?kn=80&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=61&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

Advances in sexually transmitted infections of the gastrointestinal tract
Siew C. Ng and Brian Gazzard
Published online: 25 August 2009
p592 | doi:10.1038/nrgastro.2009.143
The gastrointestinal mucosa is an important target of many sexually
transmitted infections-it is a site for HIV entry, replication and
destruction of CD4+ T cells, and provides a niche for other sexually
transmitted pathogens. This Review discusses the pathogenesis and
gastrointestinal complications of HIV infection and summarizes advances
in our understanding of other sexually transmitted infections of the
gastrointestinal system.
Abstract: http://links.ealert.nature.com/ctt?kn=78&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=62&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

Systemic amyloidosis and the gastrointestinal tract
Prayman T. Sattianayagam, Philip N. Hawkins and Julian D. Gillmore
Published online: 01 September 2009
p608 | doi:10.1038/nrgastro.2009.147
Systemic amyloidosis is characterized by the extracellular deposition
of protein in an abnormal and insoluble form. Involvement of the
gastrointestinal tract is very common but is often subclinical. This
Review describes the gastrointestinal manifestations of systemic
amyloidosis and discusses available methods for the diagnosis and
treatment of systemic amyloidosis and its gastrointestinal consequences.
Abstract: http://links.ealert.nature.com/ctt?kn=86&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=47&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

----------------------
CASE STUDY
----------------------
A case of complete resolution of gastric varices
Vanessa Tieu, George Behrens, Hector Ferral, Stanley M. Cohen and
Joseph Ahn
p618 | doi:10.1038/nrgastro.2009.144
This article considers the case of a 49-year-old woman with a history
of hepatitis C and peptic ulcer disease who presented with massive
hematemesis. She was diagnosed with gastric variceal hemorrhage and
splenic vein thrombosis. The patient underwent splenic artery
embolization and balloon-occluded retrograde transvenous obliteration
of gastric varices. By 30 months post-treatment no evidence of gastric
varices or splenic vein thrombosis remained.
Abstract: http://links.ealert.nature.com/ctt?kn=85&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=83&m=34089817&r=MTc2OTYyOTQ2MwS2&b=2&j=NTg3MjEwNTES1&mt=1&rt=0

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